Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Normothermic ex-vivo preservation with the portable [...] Replantation betreffend: a. Regenerative ex-vivo Medizin/Tissue engineering/zellbasierte Therapiestrategien b. Ex-vivo Tumortherapie (ex-vivo Strahlentherapie und Hochdosis-Chemotherapie) c. Ex-vivo Immuntherapie [...] pie (z. B. ex-vivo MHC-Silencing) d. Ex-vivo Infektionstherapie (z. B. Applikation von Hochdosis-Antibiotikatherapie) e. Ex-vivo Gentherapie (z. B. ex-vivo Korrektur von genetischen Erkrankungen) E) Vorteile

Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier [...] Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbruck L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, Sharma AD , Buning H, Ott M. Ex Vivo/In vivo Gene [...] s (selected) Markovic J, Li R, Khanal R, Peng Q, Mobus S, Yuan Q, Engel B, Taubert R, Vondran FWR, Bantel H, Singh MK, Cantz T, Buning H, Wedemeyer H, Ott M, Balakrishnan A, Sharma AD . Identification

Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Normothermic ex-vivo preservation with the portable [...] e Publikationen 1. Calabrese F, Schiavon M, Perissinotto E, Lunardi F, Marulli G, Di Gregorio G, Pezzuto F, Vuljan S, Forin E, Wiegmann B, Jonigk D, MD, Warnecke G, Rea F; Organ Care System Lung resulted [...] Sommer W, Ius F, Kunze C, Gottlieb J, Varela A, Haverich A. Normothermic perfusion of donor lungs for preservation and assessment with the Organ Care System Lung before bilateral transplantation: a pilot study

Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J , Sharma AD, Büning H, Ott M. Ex Vivo/In vivo Gene [...] S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant [...] and Results in IL-21R-like Deficiency. J Clin Immunol. 2019 Feb;39(2):207-215. 5. Stalke A, Pfister ED, Baumann U, Eilers M, Schäffer V, Illig T, Auber B, Schlegelberger B, Brackmann R, Prokisch H, Krooss

Cornelius A, Albanese M, Tagawa T, Chen YA, Krönke N , Eiz-Vesper B, Lienenklaus S, Bleich A, Theobald SJ, Schneider A, Ganser A, von Kaisenberg C, Zeidler R, Hammerschmidt W, Feuerhake F , Stripecke R. Spa [...] Cancer. 2019; 58(3): 175-185 Christians A , Adel-Horowski A, Banan R , Lehmann U , Bartels S , Behling F, Barrantes-Freer A, Stadelmann C, Rohde V, Stockhammer F, Hartmann C . The prognostic role of IDH [...] C, Golebiewska A, Zinke J, Iriondo A, Muller A, Kaoma T, Filipski K, Müller-Eschner M, Bernatz S, Blank AE, Baumgarten P, Ilina E, Grote A, Hansmann ML, Verhoff MA, Franz K, Feuerhake F , Steinbach JP

and Critical Opinion on Their Translational Impact. Ronchi, G., Ackva, C., Fregnan, F., Zen, F., Muratori, L., Crosio, A., Metzen, J., Haastert-Talini, K. (2025). International Journal of Molecular Sciences [...] Transplantation and Vascular Surgery. The work is funded by a contract of the German Armed Forces (2022-2026). We have recently established a protocol for deriving human Schwann cells from human iPSCs and [...] towards a patient-specific application in peripheral nerve repair. Key publications: Gut microbiota regulates optic nerve fiber myelination. Ronchi, G., Pellegrino, D., El Soury, M., Amato, O., Gaia, F., Farzin

Dannecker C, Dietl A, Sevnina A, Mergel F, Lotz L, Hack CC, Ehret A, Gantert D, Martignoni F, Cieslik JP, Menke J, Ortmann O, Stromberger C, Oechsle K, Hornemann B, Mumm F, Grimm C, Sturdza A, Wight E, Loessl [...] Jarkovsky J, Persson J, Raspagliesi F, Novak Z, Jaeger A, Capilna ME, Weinberger V, Klat J, Schmidt RL, Lopez A, Scibilia G, Pareja R, Kucukmetin A, Kreitner L, El-Balat A, Pereira GJR, Laufhütte S, Isla-Ortiz [...] Bousset K, Hülse F, Mao Q, Wang Y, Jentschke M, Böhmer G, Strauß HG, Hirchenhain C, Schmidmayr M, Müller F, Runnebaum I, Hein A, Stübs F, Koch M, Ruebner M, Beckmann MW, Fasching PA, Luyten A, Dürst M, Hillemanns

P, Herrmann A, Lotz J, Mengel M, Schwarz A: A blue kidney-chronic renal failure as a consequence of siderosis in paroxysmal nocturnal hemoglobinuria? Clin Nephrol 2006; 66(3): 210-3 Länger F, von Wasielewski [...] neutropenia. Nat Med 2006; 12(10): 1191-7 Stange DE, Radlwimmer B, Schubert F, Traub F, Pich A, Toedt G, Mendrzyk F, Lehmann U, Eils R, Kreipe H, Lichter P: High Resolution Genomic Profiling Reveals Association [...] V, Debertin A, Braun A, Walles T, Traub F, Pabst R: Density of dendritic cells in the human tracheal mucosa is age dependent and site specific. Thorax. 2006; 61(11): 986-91 von Wasielewski R, Klopper K

2024 Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo Abbas N, Haas JA, Xiao K, Fuchs M, Just A, Pich A, Perbellini F, Werlein C , Ius F, Ruhparwar A, Fiedler J, Weber N [...] Hartinger S, Haferlach T, Kreipe HH , Hammersen J, Hamadanchi A, Otto S, Schulze PC, Bürckenmeyer F, Teichgräber U, Hochhaus A, Witte OW, Günther A, Schrenk KG. Ann Hematol. 2024 Jan;103(1):363-365. doi: 10 [...] e Cholestasis Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek

PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus, López-Dávila A.J., Weber N., Kraft, T., Matinmehr F ., Arias-Hidalgo M., Fernández J., Lomonte [...] 2009 Aug 5;97(3):806-24. doi: 10.1016/j.bpj.2009.05.023. Seebohm B, Matinmehr F , Köhler J, Francino A, Navarro-Lopéz F, Perrot A, Ozcelik C, McKenna WJ, Brenner B, Kraft T. [...] Fibers, López-Dávila AJ, Chalovich JM, Zittrich S, Piep B, Matinmehr F , Málnási-Csizmadia A, Rauscher AÁ, Kraft T., Brenner B, Stehle R., Front Physiol. 2020 Mar 24;11:144. doi: 10.3389/fphys.2020.00144