understanding senescence biology, systematizes anti-senescence treatments, and proposes a pathway for designing clinical trials to assess their effectiveness. The publication can be found here: https://academic [...] therapeutics in nonclinical studies. These recommendations can serve as a starting point for the design of nonclinical studies and as a basis for discussions with regulatory authorities. The publication [...] cardiovascular disease. Hereby, the aim is to provide a guide to help researchers in their experimental design to translate bench findings to clinical routine taking the replacement, reduction and refinement
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run-in phase of the prospective WSG-ADAPT HR+/HER2- trial demonstrates the feasibility of a study design combinig static and dynamic biomarker assessments for individualized therapy in early breast cancer
Study protocol for a rater-blinded, randomized, controlled, multicenter trial in a 2x2 factorial design. BMC Family Practice 2020; 21: 239 Zimmermann P / Schmidt T / Nelson J / Gosemann JH / Bassler S
understanding senescence biology, systematizes anti-senescence treatments, and proposes a pathway for designing clinical trials to assess their effectiveness. The publication can be found here: https://academic [...] therapeutics in nonclinical studies. These recommendations can serve as a starting point for the design of nonclinical studies and as a basis for discussions with regulatory authorities. The publication [...] cardiovascular disease. Hereby, the aim is to provide a guide to help researchers in their experimental design to translate bench findings to clinical routine taking the replacement, reduction and refinement
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