Einer der wichtigsten Erreger der bakteriellen Meningitis ist Neisseria meningitidis der Serogruppe A (NmA). Weil die Bakterien von einer schützenden Kapsel aus Polysacchariden umgeben sind, sind sie gegen [...] Institut für Klinische Biochemie hat den Syntheseweg untersucht und herausgefunden, wie Impfstoffe gegen NmA künftig stabiler, sicherer und kostengünstiger hergestellt werden könnten. Die Studie in Kooperation [...] ion „Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A“ ist hier online verfügbar.
Local ABC-HCC A Phase IIIb, randomized, multicenter, open-label trial of Atezolizumab plus Bevacizumab versus trans arterial Chemoembolization (TACE) in intermediate-stage HCC IMMUWIN A phase II study [...] pick-the-winner design Ösophaguskarzinom/ AEG/ Magen Erstlinientherapie HERIZON-GEA-01 (ZWI-ZW25-301) A Randomized, Multicenter, Phase 3 Study of Zanidatamab in Combination with Chemotherapy with or without [...] advanced or metastatic gastroesophagal adenocarcinoma (GEA) Kolorektales Karzinom Adjuvant BNT122-01 A multi-site, open-label, Phase II, randomized, controlled trail to compare the efficacy of RO7198457
Long-COVID – a Guideline-Based Clinical Practice Guideline). Phys Med Rehab Kuror 2022; 32: 365-376 (DOI: 10.1055/a-1820-7396) Gutenbrunner C, Schiller J, Goedecke V, Lemhoefer C, Boekel A: Screening of [...] Disability Action Plan in Ukraine: Developing a National Disability, Health and Rehabilitation Plan. J Rehabil Med 2018; 50: 338-341 Nugraha B, Gutenbrunner C, Barke A, Karst M, Schiller J, Schäfer P, Falter [...] Medicine: Proposing a Fourth Factor. Am J Phys Med Rehabil 2020; 99: 436-440 Liebl ME, Gutenbrunner C, Glaesener JJ, Schwarzkopf S, Best N, Lichti G, Kraft E, Krischak G, Reißhauer A: Frühe Rehabilitation
the regulation of physiological responses to a variety of insults and serves as a protective control mechanism. The non-resolved inflammatory response plays a crucial role in the pathogenesis of many chronic [...] function and, in the long run, to the destruction of the tissues or organs involved. We search for a link between inflammation, small lipid mediators and the function and fate of beta cells. We aim to
3399/bjgp22X719681 Selter, F., Persson, K., Risse, J. et al. (2021). Dying like a dog: the convergence of concepts of a good death in human and veterinary medicine. Medicine, Health Care and Philosophy [...] Felicitas (2020). Do Animals Have a Time-Relative Interest in Continuing to Live? Paderborn: mentis. Persson, K., Selter, F., Neitzke, G., & Kunzmann, P. (2020). Philosophy of a “Good Death” in Small Animals [...] Philosophie der Medizin MHH 08/2018 Promotion (PhD) Dissertation: „Planning for the Future: Do Animals Have a Time-Relative Interest in Continuing to Live?” Betreuung: Prof. Stephan Sellmaier (LMU), Prof. Markus
experience-dependent plasticity as a prerequisite for flexible behavior. Therefore, pathology-driven changes in the ability for homeostatic plasticity expression might represent a hallmark for the development [...] Transplantation and Vascular Surgery. The work is funded by a contract of the German Armed Forces (2022-2024). We have recently established a protocol for deriving human Schwann cells from human iPSCs and [...] body conditions, which are regulated by a complex interplay of different organs. To improve the biological relevance of neuroscientific research approaches, it is a major challenge to model inter-organ
experience-dependent plasticity as a prerequisite for flexible behavior. Therefore, pathology-driven changes in the ability for homeostatic plasticity expression might represent a hallmark for the development [...] Transplantation and Vascular Surgery. The work is funded by a contract of the German Armed Forces (2022-2024). We have recently established a protocol for deriving human Schwann cells from human iPSCs and [...] body conditions, which are regulated by a complex interplay of different organs. To improve the biological relevance of neuroscientific research approaches, it is a major challenge to model inter-organ
living animals. PI: Dr. F.E. Müller , Dr. A. Zeug Recent publications: Induced Remodelling of Astrocytes In Vitro and In Vivo by Manipulation of Astrocytic RhoA Activity. Cells 2023 Elucidating regulators [...] is involved in the regulation of the serotonin system and demonstrated a reduced palmitoylation status of serotonin receptor 1A within the prefrontal cortex in post-mortem samples from depressive patients [...] health burdens in western societies and a worldwide leading cause of morbidity and mortality. The major inflammatory reaction following the ischemic insult is a key reason for high mortality rates, and
defined states of differentation as a model for colonic ion transport“, magna cum laude Dr. rer. nat. Archana Kini, MHH Oktober 2019 „Genetic ablation of anion exchanger Slc26a3 results in colonic inflammation [...] intestine in vivo " (magna cum laude) Dr. med. Xuemei Liu, MHH 2014 "Expression and function of SLC26A9 - a member of SLC26 family in the airways and gastrointestinal tract" (summa cum laude) Dr. med. Stefan [...] and Murine CF Intestine: Differential Involvement of Apical HCO3- Transporters CFTR, Slc26a3 (DRA) and Slc26a6 (PAT-1)" (summa cum laude) Dr. med. Maria Lünnemann, MHH 2011 "Molekulare Pathophysiologie
the MHH is participating in a clinical intervention study on the effectiveness of two psychotherapy methods for persistent depression (changePDD). The study is financed with a total of over € 1,700,000 and [...] Products and Medical Devices, BfArM; the Medicines Commission of the German Medical Association (AkdÄ)) and is a member of the "European Network of Centres for Pharmacoepidemiology and Pharmacovigilance" ECsPP [...] five care clinics. For this purpose, a multiprofessional team provides guidance for patients with psychiatric disorders during and after the return to work to provide a long-term support. The implemented