Simplex Virus - a hitch hiker’s guide to epithelial cells, neurons and immune cells Our group is interested in the cell biology of alpha herpesviruses. How does a virus get access to a cell, disassemble [...] studied biology in Bonn (1982-88), and obtained a Diploma in Cell Biology analyzing autophagy in the single cell animal Amoeba proteus. She then trained as a DAAD fellow (German Academic Exchange Service; [...] disassemble to release its genome for transcription and replication, and how is - within a couple of hours - the viral program switched to virus assembly and egress? Our focus is to analyze all virus-host interactions

Kim-Dorner, S. J.*, Berndt, V., Biester, T., Dehn-Hindenberg, A., Heidtmann, B., Jorch, N., Lilienthal, E., Nellen-Hellmuth, N., Neu, A., Schaaf, K., Ziegler, R., & Lange, K. (2022). Understanding daily [...] 1155/2022/9604115 Dehn-Hindenberg, A.*, Saßmann, H.*, Berndt, V., Biester, T., Heidtmann, B., Jorch, N., Kim-Dorner, S. J., Konrad, K., Lilienthal, E., Nellen-Hellmuth, N., Neu, A., Ziegler, R., & Lange, K. (2021) [...] Diabetes Care , 44 (12), 2656–2663. https://doi.org/10.2337/dc21-0740 Dehn-Hindenberg A, Saßmann H, Dierks ML, Haack M, Meyer A, Walter U, Lange K. (2020). „Die ersten drei Einträge…“ Informationsverhalten von

ADVANTAGE Managing Frailty. A comprehensive approach to promote a disability-free advanced Age in Europe: the ADVANTAGE initiative Hintergrund der Initiative 35 Organisationen aus 22 europäischen Mitg [...] Ziele: 1. Das Wesen von Frailty verstehen Mehr erfahren: Junius-Walker U et al. The essence of frailty. A systematic review and qualitative synthesis on frailty concepts and definitions. Eur J Int Med. 2018;

Düsseldorf: Georg Thieme Verlag KG (Das Gesundheitswesen). Lincke HJ, Häberle N , Lindner A, Nolle I, Vomstein M, Haug A, Kranich J, Nübling M (2020). Die Messung der emotional-affektiven Haltung zur Arbeit: [...] Ergonomie, 10(4), 482. https://doi.org/10.1007/s40664-021-00428-8 Lindner A, Lincke HJ, Vomstein M, Nolle I, Häberle N , Haug A & Nübling M (2021). Gefährdungsbeurteilung psychischer Belastungen in der [...] Häberle N, Lander J , Dierks ML and Bitzer EM (2024). Organizational health literacy in German hospitals: a cross-sectional survey among hospital managers. BMC Health Services Research (2024) 24:1227. doi.org/10

PMID: 28028135; PMCID: PMC5461802. Aue A*, Hinze C* , Walentin K, Ruffert, Yurtdas Y, Werth M, Chen W, Rabien A, Kilic E, Schulzke JD, Schumann M, Schmidt-Ott KM: A grainyhead-like 2/ovo-like 2 pathway regulates [...] C, Yilmaz DE, El-Shimy IA, Mülleder M, Hinze C , Su M, Mertins P, Kirchner M, Osmanodja B, Paliege A, Budde K, Amann K, Persson PB, Mutig K, Bachmann S. Immunosuppression with cyclosporine versus tacrolimus [...] 1111/apha.14242. Epub ahead of print. PMID: 39422260. Hinze C , Kocks C, Leiz J, Karaiskos N, Boltengagen A, Cao S, Skopnik CM, Klocke J, Hardenberg JH, Stockmann H, Gotthardt I, Obermayer B, Haghverdi L, Wyler

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qualitatives au moyen d’entretiens guidés avec 25 à 30 proches survivants, issus ou non de l’immigration. Les données des entretiens permettent une compréhension à la fois large et profonde de la thématique des [...] psychologique, notamment auprès de la population issue de la migration Contexte La pandémie de SARS-CoV-2 a fortement altéré l’accompagnement et les soins des patients mourants par les proches. Peu de recherches [...] été particulièrement touchées par la pandémie. Il n’est encore incertain si cela s’applique également à l’accompagnement en fin de vie et après le décès. Objectifs L’objectif du projet est d’appréhender la

equivalent of a master’s or diploma degree in Biology, Biochemistry or Life Sciences, or who graduated in medicine are welcome to apply. Those applicants who are selected for interviews in a first round [...] The German Research Foundation (DFG) provides funding to Hannover Medical School (MHH) to maintain a Research Training Group (RTG) (coordinator: Dirk Schlüter, Hannover). The central aim of the programme [...] their cutting-edge PhD work in the rapidly moving field of the infection biology of human pathogens in a highly stimulating, competitive and international environment. Infections are among the most common

which can serve as a screening platform to monitor increased cardiomyocyte proliferation. In addition to this novel system, we also have in vivo tools to evaluate pro-regenerative ncRNAs in a neonatal model [...] heart disease. Key references: Costa A, Hunkler HJ, Chatterjee S, Cushman S, Hilbold E, Xiao K, Lu D, Leonardy J, Juchem M, Sansonetti M, Hoepfner J, Thum T, Bär C. (2024) A reporter system for live cell tracking [...] cardiomyocyte proliferation. Cardiovasc Res. 120(14):1660-1663. https://doi.org/10.1093/cvr/cvae175 Costa A, Cushman S, Haubner BJ, Derda AA, Thum T, Bär C. (2022) Neonatal injury models: integral tools to decipher

therapeutic treatments. The group uses several in vitro and ex vivo models, with a particular focus on living myocardial slice. In a translational perspective, human myocardial slices are also extensively used [...] applied to both in vitro and in vivo research models. The group is testing these novel technologies in a regenerative medicine perspective. Working closely with the other research groups within Prof Thomas [...] development of novel therapeutic approaches HCM is the most frequent inherited cardiomyopathy with a prevalance of at least 1:500 in population. Thickening of left ventricular wall and interventricular