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Forschungsförderung Aktuelle Förderung

Viral Vectors We primarily employ integrating lentiviral and retroviral vectors, as well as non-integrating adeno-associated virus (AAV)-based particles for gene delivery. For example, we used lentivi

Living Organ Slices Our primary research focus is the advancement and refinement of the living myocardial slice (LMS) platform, a physiologically relevant model for studying cardiac function and disea

RNA-based Therapeutics RNA molecules play a critical role in a wide range of biological processes, including the initiation and progression of diseases. As a result, RNA-based therapeutics have emerge

Organ Fibrosis Organ fibrosis is a pathological condition characterized by the abnormal increase of connective tissue and excessive accumulation of extracellular matrix components, particularly collag

Lipid Nanoparticles RNA therapeutics are rapidly emerging as a key therapeutic modality. However, a major challenge for broader application remains their specific delivery to target tissues and cells,

PROTACs Classical pharmacological inhibitors can only target a small subset of proteins mainly catalytically active enzymes. Therefore, the vast majority of the proteome remains undruggable including

Superparamagnetic Nanoparticles The therapeutic potential of superparamagnetic nanoparticles has attracted great scientific interest. So far, research has been devoted to the concept of magnetic hyper