Cardiomyogenic Differentiation and Transdifferentiation By Ectopic Gene Expression - Direct Transition Or Reprogramming Detour? Curr Gene Ther 16, no. 1:14. https://doi.org/10.2174/1566523216666160104141522 [...] Myosin expression and contractile function are altered by replating stem cell-derived cardiomyocytes. J Gen Physiol 155, no. 11. https://doi.org/10.1085/jgp.202313377 . Shum, I. O., Merkert, S., Malysheva, S [...] human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line. Stem Cell Res 64:102918. #authors contributed equally. https://doi.org/10.1016/j
alcohol disorders Post mortem studies investigating the tissue-dependent regulation of essential Genes in addiction disorders Scientific Collaborations MHH-internal Cooperation with the Transplantation [...] biochemistry Epigenetics Investigations of alcohol addiction and other physical dependencies Regulation of gene expression in blood and brain Publications: Pubmed Prof. Dr. med. Thomas Hillemacher Medical Director
Science Publishers Link Kirsten Haastert-Talini Editorial for special issue: Gene Therapy approaches for Neuroregeneration Curr Gene Ther 2011 in press (Vol 11 No 2, April 2011) Ratzka A, Baron O, Grothe C [...] hypothesis. Placenta 2007;28(4):353-60. Kirsten Haastert, Claudia Grothe Gene Therapy in Peripheral Nerve Reconstruction Approaches Curr Gene Ther, 2007 Jun, 7:221-228 Grothe C and Timmer M The physiological [...] Hensel, Peter Claus, Hayat Erdem Yurter (2019): Investigations of Microtubule-associated Protein 2 Gene Expression in Spinal Muscular Atrophy. J. Pediatr. Res. 6: 148-154. Bursch F, Kalmbach N, Naujock
Feb 2;14:1145990. doi: 10.3389/fphar.2023.1145990. eCollection 2023. PMID: 36817143 Fibrosis-Related Gene Profiling in Liver Biopsies of PiZZ α1-Antitrypsin Children with Different Clinical Courses. Kamp [...] CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes. Schukfeh N, Liu B, DeLuca DS, Tumpara S, Nikolin C, Immenschuh S, Ure BM, Kuebler JF, Welte T, Viemann [...] Epub 2022 Nov 18.PMID: 36321537 Analysis of CF patient survival confirms STAT3 as a CF-modifying gene with changing impact over time. Dunsche I, Raddatz EL, Ismer H, Hedtfeld S, Tamm S, Moser S, Kontsendorn
destruction of the insulin-secreting cells. ROS generation in this destruction process is caused by gene expression changes, inhibition of enzymes or changes of the cellular redox homeostasis. In this scenario
spezialisierte morphologische Diagnostik geht Hand in Hand mit Fortschritten bei der Identifizierung von Genen, die eine Hörstörung bedingen. Durch die sehr erfolgreiche Therapie kongenital tauber Kinder mit einem
herausragende Rolle. Aufgrund des erheblichen Polymorphismus der dem HLA-Komplex zugrunde liegenden Gene können derzeit an den transplantationsrelevanten HLA-Genorten A, B, C, DRB1, DQB1 und DPB1 mehr als
5;113(6):1391-2. Theophile K, Hussein K, Kreipe H, Bock O. Expression profiling of apoptosis-related genes in megakaryocytes: BNIP3 is downregulated in primary myelofibrosis. Exp Hematol. 2008 Dec;36(12):1728-38
manipulations to explore the molecular, cellular and physiological consequences of loss- and gain-of-gene functions. All in all, this work may aid in establishing a paradigm for the molecular complexity guiding
Atemfunktion, mit einer schweren Ateminsuffizienz einher. Bis heute sind Mutationen in drei verschiedenen Genen (ATP-binding cassette protein member A3, Surfactant Proteine B und C) als Ursache bekannt. Sowohl