Brit J Haematol 2003; 123(3): 472-4 Bock O, Lehmann U, Kreipe H: Quantitative intraindividual monitoring of BCR-ABL transcript levels in archival bone marrow trephines of patients with chronic myeloid [...] Incidence of polyomavirus nephropathy in renal allografts - influence of modern immunosuppressive drugs. Nephrol Dial Transpl 2003; 18(6): 1190-6 Musholt PB, Duning T, von Wasielewski R, Marwedel M, Musholt
K, Coffee M, Beilmann M, Zweigerdt R, Mandenius CF. A cardiac cell outgrowth assay for evaluating drug compounds using a cardiac spheroid-on-a-chip device. Bioengineering (Basel). 2018;5:10.3390/bioen [...] healthy individuals and patients with acute myocardial infarction as assessed by multiple reaction monitoring-mass spectrometry. Anal Chem. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30543396 Madrahimov N,
Dahlmann F, Pöhlmann S, Vondran FW, David S, Manns MP, Ciesek S, von Hahn T. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 [...] Hohlfeld JM. Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development. BMC Pulmonary Medicine 2013.;13:19 *equal contribution Jakobi J , Bernateck M, Tran AT [...] T, Westhaus S, Rohrmann K, David S, Manns MP, Finke S, Ciesek S, von Hahn T. Cationic amphiphilic drugs enhance entry of lentiviral particles pseudotyped with rabies virus glycoprotein into non-neuronal
Laner-Plamberger, S; Streif, D; Strunk, D; Rohde, E; Gimona, M. (2017) An In Vitro Potency Assay for Monitoring the Immunomodulatory Potential of Stromal Cell-Derived Extracellular Vesicles. Int J Mol Sci. 10 [...] Beilmann, M., Zweigerdt, R., Mandenius, C.-F.(2018). A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device. Bioengineering 10.3390/bioengineering5020036 [...] Philip Nold Cell Gene Therapy Insights Expert View: Large-scale stem cell expansion and differentiation Drug Target Review & DASGIP, Philip Nold
klinischen Alltag immer wieder relevante Aspekte zu Interaktionen, Dosierung und therapeutischem Drug Monitoring nicht konsequent berücksichtigt. Dies kann nicht nur zu unerwünschten Nebenwirkungen führen, [...] zu schweren infektiösen Problemen nach Transplantation beitragen kann Trotz sehr strukturiertem Monitoring und Einsatz von CMV Prophylaktika, ergeben sich immer wieder Probleme mit rezidivierenden oder [...] T-Zellen mehr aufweisen, welche natürlich für eine effektive Elimination des Virus nötig sind. Das Monitoring und die Gabe BK Virus-spezifischer T-Zellen stellt somit eine neue Therapieoption für diese Pa
und Forschung (BMBF), National Institute for Health Research US (NIHR) and the National Institute on Drug Abuse (NIDA)) unterstützt. Weitere Informationen Leibniz AI Lab – Internationales Zukunftslabor für [...] ärztlichen Verschreibungspraxis zu gewinnen und diese im Rahmen eines intensiven Pharmakovigilanz-Monitorings an den fünf teilnehmenden Studienzentren zu bewerten. Förderung: Bundesinstitut für Arzneimittel
Division Director Preclinical Pharmacology and Toxicology, Fraunhofer ITEM: ‘Drug repurposing as a novel approach in drug development using the example of inhalative therapy against Covid-19’ 14.07.2021 [...] Dr. Constanca Figueiredo, Institute of Transfusion Medicine and Transplant Engineering, MHH ‘Of drugs and tools - novel concepts for pharmaceutical research ‘ Prof. Dr. Oliver Plettenburg, Medicinal Chemistry [...] Hannover: 'New molecular architectures based on SPIONs and maytansin: YELLOW SUBMARINES for selective drug targeting and release' 28.10.2020 - REBIRTH Kolloquium (1 pm s.t., online Vorträge) Prof. Dr. Constanca
Ophthalmologe 2019 ・ 116 (Suppl 2):S25–S218; https:// doi.org/ 10.1007/ s00347- 019- 0940-0 SD-OCT Monitoring und Visusverlauf bei Patienten mit therapierefraktärer persistierender akuter Chorioretinopathia [...] Hufendiek K. Ophthalmologe 2018 · 115(Suppl1):S1–S194; https://doi.org/10.1007/s00347-018-0760-7 SD-OCT Monitoring und Visusverlauf bei frischem Zentralarterienverschluß im Lysezeitfenster Luger B.* , Weißenborn [...] 2015;26(10):698-707 Time-Resolved Ultra-High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy. Steiner P, Ebneter A, Berger LE, Zinkernagel M, Povazay B, Meier C
Biomedical Research, Development of Regenerative Therapies and Drug Screening. In Critical Contributions of Primate Models for Biopharmaceutical Drug Development. G. Weinbauer, editor. Waxmann, Münster. Winkler [...] Christoffersson, J., Kempf, H., Zweigerdt, R. , and Mandenius, C. F. 2025. Evaluating the Effect of Drug Compounds on Cardiac Spheroids Using the Cardiac Cell Outgrowth Assay in a Microphysiological System [...] of iPSC-derived therapeutic cell products: Technologies, applications, risks and limitations. Adv Drug Deliv Rev :115744. https://doi.org/10.1016/j.addr.2025.115744 . Hashemi, M., Finklea, F. B., Hammons
Marie-Sophie Schulze Research Topic: The herpesviral DNA polymerase-associated factor as a putative drug target Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Molecular [...] Kaposi Sarcoma-associated Herpesvirus Capsid Assembly and its Thymidine Kinase as Potential Antiviral Drug Targets Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Medical [...] of phospholipase C gamma 1 by Kaposi’s sarcoma-associated herpesvirus K15 protein as a potential drug target Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Microbiology