appreciating his outstanding achievements in clinical-therapeutic drug research. Together with his team Prof. Thum developed the antisense RNA drug CDR132L which modulates gene regulation in cardiomyocytes aiming [...] to develop novel drug against cardiac fibrosis Prof. Dr. Dr. Thomas Thum receives well-respected funding award for frontier research of the European Union For his research on a novel drug against cardiac [...] anti-SASP senomorphics, and epigenetic reprogramming aim to target senescence, with some clinical drugs also showing anti-senescence effects. Our comprehensive review provides a guide to understanding

K, Coffee M, Beilmann M, Zweigerdt R, Mandenius CF. A cardiac cell outgrowth assay for evaluating drug compounds using a cardiac spheroid-on-a-chip device. Bioengineering (Basel). 2018;5:10.3390/bioen [...] healthy individuals and patients with acute myocardial infarction as assessed by multiple reaction monitoring-mass spectrometry. Anal Chem. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30543396 Madrahimov N,

Dahlmann F, Pöhlmann S, Vondran FW, David S, Manns MP, Ciesek S, von Hahn T. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 [...] Hohlfeld JM. Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development. BMC Pulmonary Medicine 2013.;13:19 *equal contribution Jakobi J , Bernateck M, Tran AT [...] T, Westhaus S, Rohrmann K, David S, Manns MP, Finke S, Ciesek S, von Hahn T. Cationic amphiphilic drugs enhance entry of lentiviral particles pseudotyped with rabies virus glycoprotein into non-neuronal

Laner-Plamberger, S; Streif, D; Strunk, D; Rohde, E; Gimona, M. (2017) An In Vitro Potency Assay for Monitoring the Immunomodulatory Potential of Stromal Cell-Derived Extracellular Vesicles. Int J Mol Sci. 10 [...] Beilmann, M., Zweigerdt, R., Mandenius, C.-F.(2018). A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device. Bioengineering 10.3390/bioengineering5020036 [...] Philip Nold Cell Gene Therapy Insights Expert View: Large-scale stem cell expansion and differentiation Drug Target Review & DASGIP, Philip Nold

und Forschung (BMBF), National Institute for Health Research US (NIHR) and the National Institute on Drug Abuse (NIDA)) unterstützt. Weitere Informationen Leibniz AI Lab – Internationales Zukunftslabor für [...] ärztlichen Verschreibungspraxis zu gewinnen und diese im Rahmen eines intensiven Pharmakovigilanz-Monitorings an den fünf teilnehmenden Studienzentren zu bewerten. Förderung: Bundesinstitut für Arzneimittel

Contextual effects of community capacity as a predictor for adolescent alcohol, tobacco, and illicit drug use: A multi-level analysis. SSM - Population Health, Volume 24, 2023, 101521. ISSN 2352-8273. https://doi [...] Contextual effects of community capacity as a predictor for adolescent alcohol, tobacco, and illicit drug use: a multi-level analysis, [Manuscript under review at SSM - Population Health]. Röding D , Birgel [...] Sammet T, Classen T, Mekel OC, Voß S, Rehfuess E, Coenen M (2024). Instrumente und Indikatoren zum Monitoring und zur Evaluation komplexer Interventionen im kommunalen Setting. Gesundheit – gemeinsam. Koo

Division Director Preclinical Pharmacology and Toxicology, Fraunhofer ITEM: ‘Drug repurposing as a novel approach in drug development using the example of inhalative therapy against Covid-19’ 14.07.2021 [...] Dr. Constanca Figueiredo, Institute of Transfusion Medicine and Transplant Engineering, MHH ‘Of drugs and tools - novel concepts for pharmaceutical research ‘ Prof. Dr. Oliver Plettenburg, Medicinal Chemistry [...] Hannover: 'New molecular architectures based on SPIONs and maytansin: YELLOW SUBMARINES for selective drug targeting and release' 28.10.2020 - REBIRTH Kolloquium (1 pm s.t., online Vorträge) Prof. Dr. Constanca

Ophthalmologe 2019 ・ 116 (Suppl 2):S25–S218; https:// doi.org/ 10.1007/ s00347- 019- 0940-0 SD-OCT Monitoring und Visusverlauf bei Patienten mit therapierefraktärer persistierender akuter Chorioretinopathia [...] Hufendiek K. Ophthalmologe 2018 · 115(Suppl1):S1–S194; https://doi.org/10.1007/s00347-018-0760-7 SD-OCT Monitoring und Visusverlauf bei frischem Zentralarterienverschluß im Lysezeitfenster Luger B.* , Weißenborn [...] 2015;26(10):698-707 Time-Resolved Ultra-High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy. Steiner P, Ebneter A, Berger LE, Zinkernagel M, Povazay B, Meier C

Marie-Sophie Schulze Research Topic: The herpesviral DNA polymerase-associated factor as a putative drug target Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Molecular [...] Kaposi Sarcoma-associated Herpesvirus Capsid Assembly and its Thymidine Kinase as Potential Antiviral Drug Targets Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Medical [...] of phospholipase C gamma 1 by Kaposi’s sarcoma-associated herpesvirus K15 protein as a potential drug target Supervisor: Prof. Dr. Thomas Schulz, Institute of Virology, MHH Academic Background: Microbiology

Biomedical Research, Development of Regenerative Therapies and Drug Screening. In Critical Contributions of Primate Models for Biopharmaceutical Drug Development. G. Weinbauer, editor. Waxmann, Münster. Winkler [...] Christoffersson, J., Kempf, H., Zweigerdt, R. , and Mandenius, C. F. 2025. Evaluating the Effect of Drug Compounds on Cardiac Spheroids Using the Cardiac Cell Outgrowth Assay in a Microphysiological System [...] derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs. Biofabrication 16, no. 3. https://doi.org/10.1088/1758-5090/ad4744 . Andrée, B. , Voß, N., Kriedemann