Interferon-lambda and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol 2015; 16: 698-707. Horst SA, Itzek A, Klos A, Beineke [...] M, Bleich A, Johnsen JM, Vallance BA, Baines JF, Grassl GA. Expression of the blood-group-related gene B4galnt2 alters susceptibility to Salmonella infection PLoS Pathog 2015; 11: e1005008. Rücker N, Billig
Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells. J Biol Chem. 2010; 285(9):6412-8 4. Poehnert D [...] Wicke DC, Meyer J, Buesche G , Heckl D, Kreipe H , Li Z, Welte KH, Ballmaier M, Baum C, Modlich U: Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia. Mol Ther. 2010;
eine erbliche Motoneuronerkrankung, hervorgerufen durch Mutationen im SMN (survival of motoneuron) Gen. Durch Verlust motorischer Nervenzellen im Rückenmark kommt es zu einer fortschreitenden Abnahme der
from a patient's symptoms down to the specific molecular mechanisms involved. Mutations in the actin genes ACTB and ACTG1 can result in developmental disorders and organ malformations collectively referred
chronisch entzündlichen ebenso wie angeborene Krankheiten betreffen und darüber hinau s. Zell- und Gen-basierte Therapien, die von der Transplantation von klassischen blutbildenden oder mesenchymalen S
Tsiavaliaris, G., Hensel, N., Viero, G., Ponimaskin, E., & Claus, P. ( 2024 ). The spinal muscular atrophy gene product regulates actin dynamics. FASEB Journal , https://doi.org/10.1096/fj.202300183R Diensthuber
Gadzicki D, v Neuhoff N, Steinemann D, Just M, Büsche G, Kreipe H, Wilkens L, Schlegelberger B: BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib [...] Serinsöz E, Bock O, Kirsch T, Haller H, Lehmann U, Kreipe H, Mengel M: Compartment-specific quantitative gene expression analysis after laser microdissection from archival renal allograft biopsies. Clin Nephrol
März 2022 bis voraussichtlich Dezember 2025 Links zu Ergebnissen des Vorläuferprojektes (GEENGOV): Gene and Genome Editing 2022 , Science & Engineering Ethics 2022 Klausurwoche „Tierversuchsethik als Z
Schwäbe FV, Pokrant T, Faix J, Di Donato N, Taft MH, Manstein DJ. Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB -associated syndromic thrombocytopenia by impairing actin
childhood myelodysplastic syndromes--challenge for the detection of chromosomal imbalances by array-CGH. Genes Chromosomes Cancer. 2010 Oct;49(10):885-900. Greten TF, Ormandy LA, Fikuart A , Höchst B, Henschen [...] stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis, Genes Dev. 2010 Aug 1;24(15):1659-72 Stankov MV1, El Khatib M1, Thakur BK, Heitmann K , Panayotova-Dimitrova [...] Bernateck M, Tran AT, Holm L, Volkmann L, Buers D, Karst M, Stuhrmann M. Catechol-O-methyltransferase gene polymorphisms are not associated with multisomatoform disorder in a group of German multisomatoform