with ARDS and septic shock. A special focus lies on evaluating current state of the art ECMO support as well as novel extracorporeal treatment modalities for septic shock. From a translational aspect, we [...] Our group was the first to prove in a murine knockout model that Angpt-2 directly contributes to sepsis morbidity and mortality. Based on this finding we have conducted a series of experiments exploring potential [...] EXCHANGE study program The hallmark of sepsis is a pathological host response to an infection that may lead to organ dysfunction, shock and ultimately to a high mortality. Besides numerous circulating mediators

to Mck2. Your profile: You hold a bachelor’s degree in a relevant field, e.g., biology, biochemistry, biomedicine. Highly motivated to fully commit to the project Exhibit a strong interest in immunology [...] expertise in a variety of involved methods, which include Cell culture Spectral flow cytometry Fluorescent microscopy CRISPR/Cas9-induced gene editing Different cell migration assays Your role: As a Master thesis [...] dynamic research and equipped with state-of-the-art laboratory facilities. We invite you to become a part of our team and contribute to an exciting and highly relevant research project. Our experienced

models. A critical overview. Eur J Neurosci 2015 Jul 30. doi: 10.1111/ejn.13033. [Epub ahead of print] Published abstracts Haastert-Talini, K., Geuna, S., Dahlin, L.B., Salgado, A.S., Shahar, A.,Freier [...] Regeneration in the Nervous System In: Int Rev Neurobiol. 2013;109C:1-62. Shahar A., Ziv-Polat O., Margel S., Freier T. Developing a Customized Tissue-Engineered Implant for Peripheral Nerve Reconstruction: Role [...] Ziv-Polat O., Morano M., Mandelbaum-Livnat M., Nissan M., Koren A., Biran T., Bitan Y., Reider E., Viano N., Rochkind S., Geuna S., Shahar A. Effect of local delivery of GDNF conjugated iron oxide nanoparticles

G.*, Roa Lara, A.*, Dahlmann, J., Zweigerdt, R., Schwanke, K., Hegermann, J., Skvorc, D., Gawol, A., Azizian, A., Wagner, S., Maier, L. S., Krause, A., Drager, G., Ochs, M., Haverich, A., Gruh, I.#, and

der Born J, Markefke S, Bauer E, von Wick A, Epping J, von Maltzahn N, Heyn-Schmidt I, Grams L, Homeyer D, Kerling A, Stiesch M, Tegtbur U, Haverich A, Melk A (2020) Gesundheit und Fitness von deutschen [...] lins B, Claas F, Dipchand A I, Eifert S, Eiz-Vesper B, Epping J, Falk C S, Foster B, Geyer S, Gjertson D, Greer M, Haubitz M, Lau A, Maecker-Kolhoff B, Memaran N, Messner H A, Ostendorf K, Samuel U, Schmidt [...] 2020;15 Melk A, Schmidt B M W, Geyer S, Epping J (2020) Sex disparities in dialysis initiation, access to waitlist, transplantation and transplant outcome in German patients with renal disease-A population

Konig A, Gordon A, Lai EC, Gingeras TR, Hannon GJ, Shcherbata HR: A genome-wide survey of sexually dimorphic expression of Drosophila miRNAs identifies the steroid hormone-induced miRNA let-7 as a regulator [...] NK, Schreek S, Cinar B, Stasche AS, Lee SH, Zeug A, Dolgner T, Niessen J, Ponimaskin E, Shcherbata H et al: SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response [...] 44(4):115434. PubMed 2024 Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, Franz P, Tsap MI, Schirmer B, Damiano-Guercio J, Hartmann FK, Plenge M, Salari A, Schöttelndreier D, Strienke K, Bresch N, Salinas

technology, we aim to design a revolutionary VAD to improve health outcomes for individuals with end-stage heart failure. Our vision is to create a next-generation VAD comprising a soft robotic sleeve powered [...] A Novel Concept of Ventricular Assist Devices (VADs) Prof. Dr. A. Ruhparwar | Prof. Dr. J. Foroughi Among the remarkable applications of smart materials in healthcare, artificial muscles epitomize innovation [...] capabilities, marking a significant advancement toward fully soft robotic VADs. This innovation holds immense potential to redefine treatment strategies for heart failure, offering a less invasive and more

Merkert S, Wunderlich S, Beier J, Franke A, Schwanke K, Göhring G, Kraft T, Francino A, Zweigerdt R, Martin U. Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy [...] doi: 10.1016/j.scr.2018.07.025. Epub 2018 Aug 18. PMID: 30145492. Koch L, Deiwick A, Franke A, Schwanke K, Haverich A, Zweigerdt R, Chichkov B.Laser bioprinting of human induced pluripotent stem cells-the [...] 090/aab981 Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, Robles-Diaz D, Coffee M, Göhring G, Dräger G, Pötz O, Joos T, Martinez-Hackert E, Haverich A, Buettner FFR, Martin U, Zweigerdt R

knowledge of students with a medical background, and likewise, provide students with a natural science background with the clinical perspective of working in translational research. Degree A PhD degree (alternatively [...] meeting usually takes place at least once a year, usually before the annual retreat. Research projects feature a clearly defined topic using suitable methods, with a realistic prospect of success and publication [...] seminars, a German crash course, and an international party. Language English is the main language of the program. German courses are offered to our international students (beginners A1 and advanced A2). And

Halle S, Keyser KA, Stahl FR, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovskii A, Kempf H, Meyer-Hermann M, Arens R [...] Pägelow D, Chhatbar C, Beineke A, Liu X, Nerlich A, van Vorst K, Rohde M, Kalinke U, Förster R, Halle S, Valentin-Weigand P, Hornef MW, Fulde M. The olfactory epithelium as a port of entry in neonatal ne [...] spontaneous formation of tertiary lymphoid structures. Nat Commun. 2022 Apr 19;13(1):2022. Rastogi A, Robert PA*, Halle S*, Meyer-Hermann M*. Evaluation of CD8 T cell killing models with computer simulations