aggressive leukemia subtype, with a 5-year overall survival (OS) of only 28% overall and certain subgroups (such as ages 65 and older) having even poorer outcomes. A metric that effectively predicts patients’ [...] malignancies, resulting in the majority of patients reaching a complete remission (CR, as assessed by imaging and light microscopy), even in AML. However, a relatively large proportion of AML patients still suffer [...] that MRD-negative AML patients – those with residual disease below a certain detection limit following initial treatment – may be at a lower risk for relapse, even without intensive or prolonged consolidation

charakterisiert. Der A1AT-Spiegel steigt während einer Entzündung oder Verletzung stark an. A1AT wird seit 30 Jahren als Substitutionstherapie bei Emphysempatienten mit genetischem A1AT-Mangel eingesetzt [...] Immunregulation, HZI Alpha-1-Antitrypsin (A1AT) ist ein Akute-Phase-Glykoprotein und einer der am häufigsten vorkommenden Protease-Inhibitoren im Menschen. A1AT wird auch als ein Protein mit breiter i [...] rten Entzündungsreaktion sind. Ziel dieses Projektes ist es, die immunmodulatorische Fähigkeit von A1AT zur Verhinderung eines klinisch schweren COVID-19-Verlaufs zu untersuchen und gleichzeitig klinisch

Initiative as a Full Professor and Director of the Institute of Molecular and Translational Therapeutic Strategies (IMTTS; Hannover Medical School). In June 2013, he was appointed as a Visiting Professor [...] heart diseases (Nature, 2008); especially he developed a strategy to block miRNA-21 to treat cardiac and extracardiac fibrosis. Thomas developed a high throughput system for massive identification of functional [...] Engagement in the Research System Thomas Thum is a physician and specialist in Internal Medicine and Cardiology trained at Hannover Medical School and Julius-Maximilians University, Würzburg. He obtained

31(7):1114-1121. Arbore G, West EE, Spolski R, Robertson AA, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann [...] complement-driven NLRP3 inflammasome activity in CD4(+) T cells. Science 2016; 352(6292):aad1210. Bajor A, Luhr A, Brockmann D, Suerbaum S, Framme C, Sedlacek L. Listeria monocytogenes endophthalmitis - case report [...] biliodigestive anastomosis. Langenbecks Arch Surg 2016; 401(5):715-724. Dupont A, Sommer F, Zhang K, Repnik U, Basic M, Bleich A, Kühnel M, Bäckhed F, Litvak Y, Fulde M, Rosenshine I, Hornef MW. Age-Dependent

order to gain a better understanding of liver regeneration, we combine longitudinal imaging analysis in vivo through an abdominal imaging window in the mouse with simultaneous manipulation on a single cell [...] aims to evaluate normothermic machine perfusion for individualized optimization of liver grafts in a porcine model. Infrastructure: Primary Human Hepatocyte (MHH) / Humanized Mouse (UKE) Core Facility [...] Research (DZIF) with hepatocytes freshly prepared from human liver tissue. The isolation of PHH is a standardized, technically complex procedure and PHH are only of limited availability. Along with PHH

Online ahead of print, PubMed Jürgens, U.J., Meißner, J.D. , Fischer, U., König, W.A., and Weckesser, J., 1987. Ornithine as a constituent of the peptidoglycan of Chloroflexus aurantiacus , diaminopimelic acid [...] Physiol., 211, 138-148. Meissner, J.D. , Chang, K.-C., Kubis, H.-P., Nebreda, A.R., Gros, G., and Scheibe, R.J., 2007. The p38a/b mitogen-activated protein kinases mediate recruitment of CREB-binding protein [...] Brandis, A., Krone, D., Schneider, H., Groos, S., Menon, M.B., Chang, K.-C., Kraft, T., Meissner, J.D. , Boheler, K.R., Maier, L.S., Gaestel, M., and Scheibe, R.J., 2013. MAPKAPK2/3 Regulate SERCA2a Expression

safety of the triplet combination of inavolisib plus a cyclin-dependent kinase 4 and 6 inhibitor (CDK4/6i; palbociclib) and letrozole versus placebo plus a CDK4/6i (palbociclib) and letrozole in the first-line [...] ositive, Her2-Negative Breast Cancer Who Have Previously Progressed During Or After A CDK4/6 Inhibitor MK2870-012 A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant [...] med. T.W. Park-Simon MAMMAKARZINOM AXSANA / EUBREAST 3 AXillary Surgery After NeoAdjuvant Treatment) A prospective multicenter cohort study to evaluate different surgical methods of axillary staging (sentinel

Gramann, M. A. Schulleitung / Lehrlogopäde dbl / Fachbereich Stimmstörungen, M.A. Sonderpädagogik (SKT) Peter Gramann, M. A. Schulleitung, Lehrlogopäde [dbl], Fachbereich Stimmstörungen M. A. Sonderpädagogik [...] Dysphagie und Z.n. Laryngektomie Birte Ripken, M. A. Lehrlogopädin dbl / Fachbereich: Redeflussstörungen Birte Ripken, M. A. Lehrlogopädin [dbl] M. A. Erwachsenenbildung Fachbereich Stottern bei Kindern [...] Bereich Kindersprache Therese Wegener, M. A. Lehrlogopädin dbl / Fachbereich: Neurologische Störungsbilder © Anna Junge Therese Wegener, M. A. Lehrlogopädin [dbl] M. A. Erwachsenenbildung Fachbereich: Neurologische

paradigms Understand sources of bias and confounding Understand how to develop a methodologically rigorous research study Develop a succinct and scientifically sound research proposal Give informed and constructive [...] for independent research. The module aims to provide a logical and systematic overview of the research process, and includes sections on developing a research question/hypothesis, choosing appropriate study [...] knowledge from a variety of sources to relate evidence to skills performance in professional practice Deeply understand complex information and issues Contents The master thesis is seen as a cumulative effort

"Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis." J Natl Cancer Inst 100(6): 437-442. Frank, B., S. H. Rigas, J. L. Bermejo, Wiestler M ., … , A. Cox and B. Burwinkel [...] General Population: A Qualitative Analysis. Nutrients 2024; 16. DOI: 10.3390/nu16172954 Peyrin-Biroulet L, Rahier JF, Kirchgesner J, … Beaugerie L; I-CARE Collaborator Group . I-CARE, a European Prospective [...] Kück M, Kerling A, Tegtbur U, Manns MP, Attaran Bandarabadi M, Bachmann O. „Quality of life is associated with wearable-based physical activity in patients with inflammatory bowel disease: A prospective,