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believed to be extinct such as tuberculosis and diphtheria meet an alarming scenario of declining rates in vaccinations as well as an increasing resistance of germs to antibiotics. Despite considerable

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due to compensatorily increased insulin biosynthesis and a concomitant increased protein folding rate. Elevated hydrogen peroxide concentrations are associated with the disruption of ER redox homeostasis

This has been linked to the enormous cellular work load resulting from the elevated insulin synthesis rate, which is connected to increased oxidative insulin folding and consequently increased luminal hydrogen

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