(Dr. med.) supervisor: PD Dr. Ott, Abt. Gastroenterology a. Hepatology, OE 6810, project: Safety and efficacy of hepatocyte transplantation in a rabbit model of hereditable hypercholesterolemia Final exam [...] Skokowa RUSSIA supervisor: Prof.Dr. R. E. Schmidt, Clinical Immunology, OE 6830, project: C5a anaphylatoxin is a major regulator of FcyRs on alveolar macrophages in immune complex induced lung injury Final

Research Our group aims at a detailed characterization of the enzyme UDP-glucose pyrophosphorylase (UGP) , a candidate drug target, from pathogenic species and the human host to identify structural and/or [...] human (Homo sapiens). PDB IDs: 4M2A , 8F73 and 4R7P. Images generated with UCSF ChimeraX. Schemes of organisms from Servier Medical Art, provided by Servier, licensed under a Creative Commons Attribution 3 [...] and/or mechanistic differences that would allow the development of specific inhibitors targeting UGP as a novel anti-infective drug target. We have previously studied UGP from the protozoan parasite Leishmania

Struve B, Wassermann L, Heider M, Weegh N, Knape T, Hofmann MCJ, von Knethen A, Jirkof P, Häger C and Bleich A (2022) RELSA—A multidimensional procedure for the comparative assessment of well-being and [...] R. Talbot. A model-specific simplification of the Mouse Grimace Scale based on the pain response of intraperitoneal CCl4 injections. Sci Rep 12, 10910 (2022). Zentrich E, Talbot SR , Bleich A and Häger [...] During Acute Experimental Colitis in Mice. Front. Neurosci.. 2021; 15:760606. Helgers, S.O.A., Talbot, S.R. , Riedesel, A. et al. Body weight algorithm predicts humane endpoint in an intracranial rat glioma

Iorga B., Fischer M., Geers-Knörr C., Hegermann J., Wrede C., Fiedler J., Kempf H., Franke A., Piep B., Pfanne A., Thum T., Martin U., Brenner B., Zweigerdt R., Kraft T. (2016) “Stiff matrix induces switch [...] (ISSN: 0022-1295), Vol.137(3):255-270 PubMed Iorga B., Blaudeck N., Solzin J., Neulen A., Stehle I., Lopez-Davila A. J., Pfitzer G., Stehle R. (2008) “Lys184 deletion in troponin I impairs relaxation kinetics [...] 77:676-686 PubMed Roels B., Reggiani C., Reboul C., LionneC., Iorga B., Obert P., Tanguy S., Gibault A., Jougla A., Travers F., Millet G., Candau R. (2008) “Paradoxial effects of endurance training and chronic

Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus, López-Dávila A.J., Weber N., Kraft, T., Matinmehr F ., Arias-Hidalgo M., Fernández J [...] 5;97(3):806-24. doi: 10.1016/j.bpj.2009.05.023. Seebohm B, Matinmehr F , Köhler J, Francino A, Navarro-Lopéz F, Perrot A, Ozcelik C, McKenna WJ, Brenner B, Kraft T. [...] Slow-Twitch Fibers, López-Dávila AJ, Chalovich JM, Zittrich S, Piep B, Matinmehr F , Málnási-Csizmadia A, Rauscher AÁ, Kraft T., Brenner B, Stehle R., Front Physiol. 2020 Mar 24;11:144. doi: 10.3389/fphys

immune environment in BTC and PDAC by systemic therapies’, we are looking for a medical student and a PhD student for 10/2025. A call for applications will be published soon. Stay tuned! Funding Press Max [...] inoma’, funded by the Else Kröner Memorial Scholarship. The position comes with a stipend for the student and requires a 9-month suspension from studies analogous to the StrucMed programme (Hannover Medical [...] hepato-pancreaticobiliary tumours and liver metastases. The aim of the Heinrich research group is to gain a precise understanding of the immune network in the tumour environment, taking into account influencing

Tsiavaliaris, G. (2010). Targeted optimization of a molecular motor for controlling movement in biohybrid devices. Biophys. J. 01/2010; 98(3-3, Supplement 1):606a. DOI: 10.1016/j.bpj.2009.12.3301 Kathmann, D [...] Switch-2 dependent modulation of the myosin power stroke. Biophys. J. 01/2010; 98 (3-3, Supplement 1):143a-144a. DOI: https://10.1016/j.bpj.2009.12.773 G. Tsiavaliaris. Molecular and cellular dissection of class-1 [...] g of myosin motors. May 2014, Linnaeus University- Dept. Chemistry and Biomedical Sciences , Prof. A. Mansson, Sweden. G. Tsiavaliaris. Nicotiana tabacum myosin-11: unraveling the kinetic mechanism of

und verabschiedeten die Promovenden mit „Happy“ von Pharrell Williams. „A transposable element protects a patient from developing a severe hemophilia B and provides insights into separation of New- and Old [...] haben, der zu einer Erzeugung eines alternativen Poly(A)-Signals in der F9 3'UTR kurz nach der Trennung führte. Daher dient das alternative Poly(A)-Signal im oben beschriebenen Transposon als wichtiger [...] mobiles genetisches Element, ein sogenanntes Transposon, die Polyadenylierung für das mutierte Poly(A)-Signal, wodurch eine ausreichende F9-mRNA-Synthese erzielt wird. Speziesübergreifende Sequenzanalysen

Towards a better understanding „Easy German Language as a means to improve German Health Literacy” 14. Januar 2020 Johannes Gutenberg Universität Mainz; Standort Germersheim Gastvortrag im B.A. Sprache [...] tin und -assistentin für Englisch und Französisch (Schwerpunkt Wirtschaft) B.A. Translation an der Universität Leipzig M.A. Medientext und Medienübersetzung an der Universität Hildesheim Wissenschaftliche

Die Studie untersucht Therapiemöglichkeiten von Clusterkopf-schmerzen. Januar 2018 A SURGICAL HISTORICAL EXHIBITION: A short history of movement disorders surgery Titelseite Die Funktionelle Neurochirurgie [...] ion besteht nun seit 30 Jahren. Zu diesem Anlass wurde das Booklet mit dem Titel „A SURGICAL HISTORICAL EXHIBITION: A short history of movement disorders surgery“ von Joachim K. Krauss, Marwan I. Hariz [...] Study: Randomized, Multicenter Trial to Evaluate the Quality of Ventricular Catheter Placement with a Mobile Health Assisted Guidance Technique“ , der unter aktiver Mitwirkung von PD Dr. med. E. Hermann