Völkel A, Hoffmann F. Implementation, barriers, and recommendations for further development of advance care planning for the last phase of life in nursing homes in Germany (Gut-Leben): protocol for a mix [...] male nursing home residents: Results from a nationwide cross-sectional survey in Germany. Urol Int. 2024 Nov 18:1-7 doi: 10.1159/000542430. Berloge C, Völkel A, Jacobs H, Burger B, Jona T Stahmeyer JT, [...] planning for residents in German nursing homes – A cross-sectional study. BMC Geriatr 2024;24:999 doi: 10.1186/s12877-024-05578-x. Wandscher K, Jacobs H, Völkel A, Schleef T, Stahmeyer JT, Burger B, Brütt AL

Research Our group aims at a detailed characterization of the enzyme UDP-glucose pyrophosphorylase (UGP) , a candidate drug target, from pathogenic species and the human host to identify structural and/or [...] human (Homo sapiens). PDB IDs: 4M2A , 8F73 and 4R7P. Images generated with UCSF ChimeraX. Schemes of organisms from Servier Medical Art, provided by Servier, licensed under a Creative Commons Attribution 3 [...] and/or mechanistic differences that would allow the development of specific inhibitors targeting UGP as a novel anti-infective drug target. We have previously studied UGP from the protozoan parasite Leishmania

(Dr. med.) supervisor: PD Dr. Ott, Abt. Gastroenterology a. Hepatology, OE 6810, project: Safety and efficacy of hepatocyte transplantation in a rabbit model of hereditable hypercholesterolemia Final exam [...] Skokowa RUSSIA supervisor: Prof.Dr. R. E. Schmidt, Clinical Immunology, OE 6830, project: C5a anaphylatoxin is a major regulator of FcyRs on alveolar macrophages in immune complex induced lung injury Final

1186/s13054-021-03584-8. PMID: 33931122 Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA. Autonomous Calcium Signaling in Human [...] print. PMID: 33911000 Etzrodt V, Idowu TO, Schenk H, Seeliger B, Prasse A, Thamm K, Pape T, Müller-Deile J, van Meurs M, Thum T, Garg A, Geffers R, Stahl K, Parikh SM, Haller H, David S. Role of endothelial [...] Bräsen JH, Haller H, Schiffer M. Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model. Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5. PMID: 31776394 Stahl

countries: a panel data analysis. BMJ Open 2024;14:e077765. doi:10.1136/bmjopen-2023-077765 Bartling T , Oedingen C, Schrem H, Kohlmann T, Krauth C (2023). Setting Organ Allocation Priorities: A Discrete [...] allocation: a discrete choice experiment regarding distributive justice. The Patient. 15(6):729-738. Doi: 10.1007/s40271-022-00601-y. Bartling T , Oedingen C, Schrem H, Kohlmann T, Krauth C (2021). ‘As a surgeon [...] C, Bartling T , Dreier M, Spura A, de Bock F, von Rüden U, Betsch C, Korn L, Robra B-P (2021). Public Preferences for exit strategies from COVID-19 lockdown in Germany—A discrete choice experiment. Int

Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus, López-Dávila A.J., Weber N., Kraft, T., Matinmehr F ., Arias-Hidalgo M., Fernández J [...] 5;97(3):806-24. doi: 10.1016/j.bpj.2009.05.023. Seebohm B, Matinmehr F , Köhler J, Francino A, Navarro-Lopéz F, Perrot A, Ozcelik C, McKenna WJ, Brenner B, Kraft T. [...] Slow-Twitch Fibers, López-Dávila AJ, Chalovich JM, Zittrich S, Piep B, Matinmehr F , Málnási-Csizmadia A, Rauscher AÁ, Kraft T., Brenner B, Stehle R., Front Physiol. 2020 Mar 24;11:144. doi: 10.3389/fphys

aster: 4 mm DIN A5 Broschüre (148 x 210 mm) 10 Spalten, Spaltenbreite 8,5 mm, Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13 mm, Innen 19 mm, Außen 8 mm Grundlinienraster: 4 mm 1/3 DIN A4 Broschüre (99 x [...] und Anordnung von Bildern regelt. Schriftgrößen und Satzangaben finden Sie im Kapitel Schrift. DIN A4 Broschüre (210 x 297 mm) 12 Spalten, Spaltenbreite 10 mm, Stegbreite 5 mm Ränder: Oben 9 mm, Unten [...] Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13 mm, Innen 9 mm, Außen 6 mm Grundlinienraster: 4 mm 1/3 DIN A4 Faltblatt (99 x 210 mm) 8 Spalten, Spaltenbreite 7 mm, Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13

Local ABC-HCC A Phase IIIb, randomized, multicenter, open-label trial of Atezolizumab plus Bevacizumab versus trans arterial Chemoembolization (TACE) in intermediate-stage HCC IMMUWIN A phase II study [...] Subjects with HER2+ Metastatic Colorectal cancer Gallengangs- bzw. Cholangiokarzinom Lokal IMMUWHY A phase II study of immunotherapy with durvalumab (MEDI4736) or durvalumab and tremelimumab, both combined [...] ablation via catheter and transpapillary access in patients with cholangiocarcinoma (ACTICCA-2 trial) . A randomized, open-label investigator-initiated trial Clean-Duct/ TRITICC-3 Phase IIa, prospective, single

Projects Allosteric regulation of UDP-sugar pyrophosphorylases as a means to develop new anti-parasitic treatments UDP-sugar pyrophosphorylases play a central role in cellular carbohydrate biosynthesis. As metabolic [...] innate immune sensors as a means to control infection and inflammation The innate immune sensors activate interferon-driven antiviral responses upon recognition of PAMPs and serve as a rheostat for the metabolic [...] development of new drugs against protozoan parasites. The current project pursues the goal to obtain a comprehensive description of the allosteric mechanisms regulating UDP-sugar pyrophosphorylases in the

Towards a better understanding „Easy German Language as a means to improve German Health Literacy” 14. Januar 2020 Johannes Gutenberg Universität Mainz; Standort Germersheim Gastvortrag im B.A. Sprache [...] tin und -assistentin für Englisch und Französisch (Schwerpunkt Wirtschaft) B.A. Translation an der Universität Leipzig M.A. Medientext und Medienübersetzung an der Universität Hildesheim Wissenschaftliche