Tourette-Syndrome: Results from a Cerebrospinal Fluid Study. Front Neurol. 2019 Jul 4; 10:732. Sühs KW, Novoselova N, Kuhn M, Seegers L, Kaever V, Muller-Vahl K, et al. Kynurenine is a cerebrospinal fluid biomarker [...] J Neuropathol Exp Neurol 2014 Jun;73(6):507-18. Sühs KW, Hein K, Sattler MB, Gorlitz A, Ciupka C, Scholz K, et al. A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis. Ann Neurol [...] infections. J Infect Dis 2019 Jun 5; 220(1):127-138. Sühs KW, Fairless R, Williams SK, Heine K, Cavalie A, Diem R. N-methyl-D-aspartate receptor blockade is neuroprotective in experimental autoimmune optic

Projects Allosteric regulation of UDP-sugar pyrophosphorylases as a means to develop new anti-parasitic treatments UDP-sugar pyrophosphorylases play a central role in cellular carbohydrate biosynthesis. As metabolic [...] innate immune sensors as a means to control infection and inflammation The innate immune sensors activate interferon-driven antiviral responses upon recognition of PAMPs and serve as a rheostat for the metabolic [...] development of new drugs against protozoan parasites. The current project pursues the goal to obtain a comprehensive description of the allosteric mechanisms regulating UDP-sugar pyrophosphorylases in the

Struve B, Wassermann L, Heider M, Weegh N, Knape T, Hofmann MCJ, von Knethen A, Jirkof P, Häger C and Bleich A (2022) RELSA—A multidimensional procedure for the comparative assessment of well-being and [...] R. Talbot. A model-specific simplification of the Mouse Grimace Scale based on the pain response of intraperitoneal CCl4 injections. Sci Rep 12, 10910 (2022). Zentrich E, Talbot SR , Bleich A and Häger [...] During Acute Experimental Colitis in Mice. Front. Neurosci.. 2021; 15:760606. Helgers, S.O.A., Talbot, S.R. , Riedesel, A. et al. Body weight algorithm predicts humane endpoint in an intracranial rat glioma

Local ABC-HCC A Phase IIIb, randomized, multicenter, open-label trial of Atezolizumab plus Bevacizumab versus trans arterial Chemoembolization (TACE) in intermediate-stage HCC IMMUWIN A phase II study [...] Subjects with HER2+ Metastatic Colorectal cancer Gallengangs- bzw. Cholangiokarzinom Lokal IMMUWHY A phase II study of immunotherapy with durvalumab (MEDI4736) or durvalumab and tremelimumab, both combined [...] ablation via catheter and transpapillary access in patients with cholangiocarcinoma (ACTICCA-2 trial) . A randomized, open-label investigator-initiated trial Clean-Duct/ TRITICC-3 Phase IIa, prospective, single

Tsiavaliaris, G. (2010). Targeted optimization of a molecular motor for controlling movement in biohybrid devices. Biophys. J. 01/2010; 98(3-3, Supplement 1):606a. DOI: 10.1016/j.bpj.2009.12.3301 Kathmann, D [...] Switch-2 dependent modulation of the myosin power stroke. Biophys. J. 01/2010; 98 (3-3, Supplement 1):143a-144a. DOI: https://10.1016/j.bpj.2009.12.773 G. Tsiavaliaris. Molecular and cellular dissection of class-1 [...] g of myosin motors. May 2014, Linnaeus University- Dept. Chemistry and Biomedical Sciences , Prof. A. Mansson, Sweden. G. Tsiavaliaris. Nicotiana tabacum myosin-11: unraveling the kinetic mechanism of

und verabschiedeten die Promovenden mit „Happy“ von Pharrell Williams. „A transposable element protects a patient from developing a severe hemophilia B and provides insights into separation of New- and Old [...] haben, der zu einer Erzeugung eines alternativen Poly(A)-Signals in der F9 3'UTR kurz nach der Trennung führte. Daher dient das alternative Poly(A)-Signal im oben beschriebenen Transposon als wichtiger [...] mobiles genetisches Element, ein sogenanntes Transposon, die Polyadenylierung für das mutierte Poly(A)-Signal, wodurch eine ausreichende F9-mRNA-Synthese erzielt wird. Speziesübergreifende Sequenzanalysen

immune environment in BTC and PDAC by systemic therapies’, we are looking for a medical student and a PhD student for 10/2025. A call for applications will be published soon. Stay tuned! Funding Press Max [...] inoma’, funded by the Else Kröner Memorial Scholarship. The position comes with a stipend for the student and requires a 9-month suspension from studies analogous to the StrucMed programme (Hannover Medical [...] hepato-pancreaticobiliary tumours and liver metastases. The aim of the Heinrich research group is to gain a precise understanding of the immune network in the tumour environment, taking into account influencing

aster: 4 mm DIN A5 Broschüre (148 x 210 mm) 10 Spalten, Spaltenbreite 8,5 mm, Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13 mm, Innen 19 mm, Außen 8 mm Grundlinienraster: 4 mm 1/3 DIN A4 Broschüre (99 x [...] und Anordnung von Bildern regelt. Schriftgrößen und Satzangaben finden Sie im Kapitel Schrift. DIN A4 Broschüre (210 x 297 mm) 12 Spalten, Spaltenbreite 10 mm, Stegbreite 5 mm Ränder: Oben 9 mm, Unten [...] Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13 mm, Innen 9 mm, Außen 6 mm Grundlinienraster: 4 mm 1/3 DIN A4 Faltblatt (99 x 210 mm) 8 Spalten, Spaltenbreite 7 mm, Stegbreite 4 mm Ränder: Oben 9 mm, Unten 13

countries: a panel data analysis. BMJ Open 2024;14:e077765. doi:10.1136/bmjopen-2023-077765 Bartling T , Oedingen C, Schrem H, Kohlmann T, Krauth C (2023). Setting Organ Allocation Priorities: A Discrete [...] allocation: a discrete choice experiment regarding distributive justice. The Patient. 15(6):729-738. Doi: 10.1007/s40271-022-00601-y. Bartling T , Oedingen C, Schrem H, Kohlmann T, Krauth C (2021). ‘As a surgeon [...] C, Bartling T , Dreier M, Spura A, de Bock F, von Rüden U, Betsch C, Korn L, Robra B-P (2021). Public Preferences for exit strategies from COVID-19 lockdown in Germany—A discrete choice experiment. Int

Iorga B., Fischer M., Geers-Knörr C., Hegermann J., Wrede C., Fiedler J., Kempf H., Franke A., Piep B., Pfanne A., Thum T., Martin U., Brenner B., Zweigerdt R., Kraft T. (2016) “Stiff matrix induces switch [...] (ISSN: 0022-1295), Vol.137(3):255-270 PubMed Iorga B., Blaudeck N., Solzin J., Neulen A., Stehle I., Lopez-Davila A. J., Pfitzer G., Stehle R. (2008) “Lys184 deletion in troponin I impairs relaxation kinetics [...] 77:676-686 PubMed Roels B., Reggiani C., Reboul C., LionneC., Iorga B., Obert P., Tanguy S., Gibault A., Jougla A., Travers F., Millet G., Candau R. (2008) “Paradoxial effects of endurance training and chronic