Elective course I: Biology / Genetics

Module code: WP 235

Compulsory elective course with min. 5 to max. 12 participants

Topic: Basics of genetic diagnostics and gene therapy

Type and scope of the courses

28 hours seminar (Selected topics: What should be considered in genetic counseling? How does genetic cancer develop? Selected current examples of gene therapy).
with practical components / laboratory visit (genetic diagnostics using the example of RFLP (restriction fragment length poly-morphisms), diagnostic gel electrophoresis of nucleic acids, visualization of viral gene shuttles, visualization of gene therapy/gene modification).

Academic year / tertial / times:

Start: Every year in October

The exact dates will be communicated by the Office of Academic Affairs Medicine

Location: Seminar room of the HBZ, building J11, level S0

Date: Fridays 15:00 - 17:00

Teaching supervisor

Dr. rer. nat. Michael Morgan, Experimental Haematology, OE 6960, Tel.: 532-5139, Morgan.Michael@mh-hannover.de

Prof. Dr. med. Axel Schambach, Experimental Haematology, OE 6960, Tel.: 532-5170, schambach.axel@mh-hannover.de

Assignment to the study programmes

Human medicine

Entry requirements

Successful participation in the Biology for Physicians internship

Academic achievements/learning objectives

Understanding of molecular genetic principles, introduction to the problems involved in carrying out genetic analyses and counseling, introduction to somatic gene therapy as a causal approach to genetic diseases

Course contents

Procedure for genetic diagnostics and patient counseling

Insight into the procedure for gene therapy of selected diseases

Introduction to the technical and ethical problems

Practical exercises in the laboratory / "laboratory rounds"

Examination

Form of examination: oral (presentation, participation in seminar)

Date of examination: by arrangement

Repeat dates: by arrangement

Didactic aids

Literature (in the form of current publications) is provided

Recommended literature

(Current publications will be provided as a basis for the seminars)

Basic works:

1. Tom Strachan, Andrew P. Read, Molekulare Humangenetik, Elsevier Spektrum Akademischer Verlag, 2004

2. Passarge E, Pocket Atlas of Genetics. Stuttgart: Thieme, 2004