Dr. rer. nat. Svenja Bothe
Studies and academic training
- 2020-2025 Doctoral studies (Dr. rer. nat.), Clinical Department of Neurology, Hannover Medical School
- 2018-2020 Master of Science (M.Sc.) Life Science, Gottfried Wilhelm Leibniz Universität Hannover
- 2014-2018 Bachelor of Science (B.Sc.) Life Science, Gottfried Wilhelm Leibniz University Hannover
Scientific career
- Since 04/2025 Research Associate/PostDoc, Institute of Neuroanatomy and Cell Biology, Hannover Medical School
- 10/2020-03/2025 Doctoral student, Clinical Department of Neurology
- 01/2019-06/2019 Research assistant (ERASMUS internship abroad), Marine Biodiscovery Center (MBC), Aberdeen, Scotland
- 10/2017-09/2020 Research Associate, Institute for Food Chemistry, Leibniz University Hannover, Germany
Prizes and awards
- 2017 Solvay Scholarship for special achievements in the Faculty of Natural Sciences
Scientific focus
- Extracellular vesicles and synaptic plasticity: Focus on the role of extracellular vesicles (especially exosomes) as mediators of intercellular Communications in the central nervous system
- Establishment of neurofilament light chain (NfL) as a biomarker for neuroaxonal damage in cell culture models
Online presence
ORCID: 0009-0001-2006-9510
Publications
A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson's disease cell model. Höllerhage, M., Duan, L., Chua, O.W.H., Moebius, C., Bothe, S.H., Losse, K., Kotzur, R., Lau, K., Hopfner, F., Richter, F., Wahl-Schott, C., Bickle, M., and Höglinger, G.U. (2025a). Transl Neurodegener 14, 27. https://doi.org10.1186/s40035-025-00486-5
Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity. Höllerhage, M., Chua, O.W.H., Duan, L., Bothe, S., Evsyukov, V., Moebius, C., Bickle, M., and Höglinger, G. (2025b). https://doi.org10.21203/rs.3.rs-6867964/v1