Experimental Haematology(BM WP 05)
Qualification objectives
The module provides students with basic knowledge and in-depth knowledge of the structure of hematopoiesis (blood system) and the genetic modification of hematopoietic cells. Students are familiar with the most important methods of experimental hematology, gene therapy, molecular biology and cell biology.
Competencies
Lecture: Students know the structure of the blood system and the underlying control molecules, such as transcription factors and cytokines. They also have an understanding of how the blood system develops embryologically and in the adult organism from blood stem cells. They also have skills in the genetic modification of cells, e.g. for therapeutic or experimental purposes.
Internship: Students know the sites of hematopoiesis in the adult organism and can cultivate blood cells. They have an understanding of the differentiation of blood cells in the so-called "colony assay" and have skills in the genetic modification of cells. They know how to produce retroviral and lentiviral vectors, use them to transduce cells and demonstrate successful gene transfer