Neurogenetics
Head: Priv.-Doz. Dr. med. Franziska Hopfner
Staff members: Valentin Evsyukov, Johanne Heine, Sabine Lang, Mojtaba Nemati
The research group investigates the genetic and epigenetic basis and molecular mechanisms of neurological diseases. Our aim is to improve their diagnosis and, in the long term, to offer our patients individualized treatment tailored to their needs. We focus in particular on research into neurodegenerative diseases and tremor syndromes.
In our research projects, we combine the clinical-phenomenological findings that we have gained from examining our patients with information from genetic and epigenetic analyses.
A better understanding of the genetic predisposition and its interaction with environmental influences enables us to decipher the development of the disease.
The spectrum of methods includes array-based genotyping procedures, next-generation sequencing and traditional cell biology methods. The data information obtained is then used in projects that analyze large data sets bioinformatically and statistically.
We carry out clinical and genetic/epigenetic research projects in the Clinical Department of Neurology and the affiliated laboratory facilities at Hannover Medical School.
We are closely linked to clinical and basic science partners.
- German Society for Parkinson's and Movement Disorders
- International Parkinson and Movement Disorder Society
- German Center for Neurodegenerative Diseases
- Institute of Molecular Biology at the University of Kiel
- Neurogenetics Working Group of the Clinical Department of Neurology at Kiel University
- Center for Neuropathology and Prion Research at the LMU Munich
- Center National de Recherche en Génomique Humaine, France
We currently receive research funding from the following national and international funding institutions:
- German Research Foundation
- German Society for Parkinson's and Movement Disorders
- German Federal Ministry of Education and Research
- European Union's Horizon 2020 research and innovation program
- CurePSP Foundation
- Erwin Röver Foundation
- COVID-19 Research Network Lower Saxony
- Else Kröner-Fresenius Foundation
Contact:
Priv.-Doz. Dr. med. Franziska Hopfner
Hannover Medical School
Clinical Department of Neurology
Senior physician
OE 7210, Carl-Neuberg-Str. 1, 30625 Hanover, Germany
Phone: +49 511 532 2390
hopfner.franziska@mh-hannover.de
To the publications: