Primary URECs: a source to better understand the pathology of renal tubular epithelia in pediatric hereditary cystic diseases.
Ziegler WH, Lüdiger S, Hassan F, Georgiadis ME, Swolana K, Khera A, Mertens A, Franke D, Wohlgemuth K, Dahmer-Heath M, König J, Dafinger C, Liebau MC, Cetiner M, Bergmann C, Soetje B, Haffner D. Orphanet J Rare Dis. 2022; 17:122.
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Fibrocystin is essential to cellular control of adhesion and epithelial morphogenesis.
Ziegler WH, Soetje B, Marten LP, Wiese J, Burute M, Haffner D. Int J Mol Sci. 2020; 21:5140.
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Application and Comparison of Supervised Learning Stratagies to Classify Polarity of Epithelial Cell Spheroids in 3D Culture.
Soetje B, Fuellekrug J, Haffner D, Ziegler WH. Front Genet. 2020; 11: 248.
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Network for Early Onset Cystic Kidney Diseases-A Comprehensive Multidisciplinary Approach to Hereditary Cystic Kidney Diseases in Childhood.
König JC, Titieni A, Konrad M; NEOCYST Consortium. Front Pediatr. 2018; 6:24.
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Transition of responsive mechanosensitive elements from focal adhesion to adherens junctions on epithelial differentiation.
Noethel B, Ramms L, Dreissen G, Hoffmann M, Springer R, Rübsam M, Ziegler WH, Niessen CM, Merkel R, Hoffmann B. Mol Biol Cell. 2018; 29: 2317-2325.
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E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.
Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Fufresne ER, Moser M, Ziegler W, Amagai M, Wickström SA, Niessen CM. Nat Commun. 2017; 8; 1250.
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TIMP3 is Regulated by Pericytes upon Shear Stress Detection Leading to a Modified Endothelial Cell Response.
Schrimpf C, Koppen T, Duffield JS, Böer U, David S, Ziegler W, Haverich A, Teebken OE, Wilhelmi M. Eur J Vasc Endovasc Surg. 2017; 54: 524-533.
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Flunarizine suppresses endothelial angiopoietin-2 in a calcium-dependent fashion in sepsis.
Retzlaff J, Thamm K, Ghosh CC, Ziegler W, Haller H, Parikh SM, David S. Sci Rep. 2017; 7: 44113.
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Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices.
Mierke CT, Fischer T, Puder S, Kunschmann T, Soetje B, Ziegler WH. Sci Rep. 2017; 7: 42780.
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Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease.
Leifheit-Nestler M, Große Siemer R, Flasbart K, Richter B, Kirchhoff F, Ziegler WH, Klintschar M, Becker JU, Erbersdobler A, Aufricht C, Seeman T, Fischer DC, Faul C, Haffner D. Nephrol Dial Transplant. 2016; 31: 1088-99.
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Deletion of the cell adhesion adaptor protein vinculin disturbs the localization of GFAP in Bergmann glial cells.
Winkler U, Hirrlinger PG, Sestu M, Wilhelm F, Besser S, Zemljic-Harpf AE, Ross RS, Bornschein G, Krügel U, Ziegler WH, Hirrlinger J. Glia. 2013; 61: 1067-83.
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Integrin-mediated internalization of Staphylococcus aureus does not require vinculin.
Borisova M, Shi Y, Buntru A, Wörner S, Ziegler WH, Hauck CR. BMC Cell Biol. 2013; 14: 2. doi: 10.1186/1471-2121-14-2.
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Metavinculin: New insights into functional properties of a muscle adhesion protein.
Thoss F, Dietrich F, Punkt K, Illenberger S, Rottner K, Himmel M, Ziegler WH. Biochem Biophys Res Commun. 2013; 430: 7-13.
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The Cytoskeletal Connection: Understanding Adaptor Proteins.
Ziegler WH. Transl Res Biomed. Basel, Karger. 2010; 2: 136-162.
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