COVID-19 / SARS-CoV-2 Research at the MHH On this website we present the research studies and research achievements at the MHH on COVID-19. COVID-19 / SARS-CoV-2 Research at the MHH The MHH research team of Prof. Dr. Christian Könecke (on the right) publishes first European study of this kind in the Lancet journal "EBioMedicine". COVID-19 / SARS-CoV-2 Research at the MHH Research group of Prof. Dr. Reinhold Förster develops a simple test to detect protective neutralizing antibodies. COVID-19 / SARS-CoV-2 Research at the MHH From basic research to supramaximal care In addition to the research topics on Transplantation and Regeneration or Biomedical Engineering as well as Implants, the Hannover Medical School (MHH) is also well-known for the Infection Research . The MHH possesses a big network through partnerships with the Helmholtz Center for Infection Research (HZI), memberships in German Centers for Health Research as well as various collaborative research centers, the Cluster of Excellence RESIST and the HiGHmed Consortium. The MHH has lots of excellent internal (at the Campus), national and international collaborative research projects. The latter is also illustrated by the broad research funding of the MHH. to the projects Contact Coordination Local Coordination Unit (LokS) Patrick Kaufhold, Assistant Project Management E-Mail: num-loks @ mh-hannover.de Tel.: +49 (0) 511 532 83764 Dr. Tetyana Yevsa, Head of LokS E-Mail: num-loks @ mh-hannover.de Tel.: +49 (0) 511 532 83164 Publications on COVID-19 / SARS-CoV-2 research at the MHH sorted by a PubMed-ID (PMID) Publications with the PMID: 32143123 - 33368589 Cordes AK, Heim A. Rapid random access detection of the novel SARS-coronavirus-2 (SARS-CoV-2, previously 2019-nCoV) using an open access protocol for the Panther Fusion. J Clin Virol 2020;125:104305 DOI: S1386-6532(20)30047-0 Zhang L, Lin D, Sun X, Curth U, Drosten C, Sauerhering L, Becker S, Rox K, Hilgenfeld R. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors. Science 2020;368(6489):409-412 DOI: 10.1126/science.abb3405 Wollenberg A, Flohr C, Simon D, Cork MJ, Thyssen JP, Bieber T, de Bruin-Weller MS, Weidinger S, Deleuran M, Taieb A, Paul C, Trzeciak M, Werfel T, Seneschal J, Barbarot S, Darsow U, Torrelo A, Stalder JF, Svensson A, Hijnen D, Gelmetti C, Szalai Z, Gieler U, De Raeve L, Kunz B, Spuls P, von Kobyletzki LB, Folster-Holst R, Chernyshov PV, Christen-Zaech S, Heratizadeh A, Ring J, Vestergaard C. European Task Force on Atopic Dermatitis statement on severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection and atopic dermatitis. J Eur Acad Dermatol Venereol 2020;34(6):e241-e242 DOI: 10.1111/jdv.16411 Albano D, Bertagna F, Bertoli M, Bosio G, Lucchini S, Motta F, Panarotto MB, Peli A, Camoni L, Bengel FM, Giubbini R. Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region. J Nucl Med 2020;61(5):632-636 DOI: 10.2967/jnumed.120.246256 Angus DC, Berry S, Lewis RJ, Al-Beidh F, Arabi Y, van Bentum-Puijk W, Bhimani Z, Bonten M, Broglio K, Brunkhorst F, Cheng AC, Chiche JD, De Jong M, Detry M, Goossens H, Gordon A, Green C, Higgins AM, Hullegie SJ, Kruger P, Lamontagne F, Litton E, Marshall J, McGlothlin A, McGuinness S, Mouncey P, Murthy S, Nichol A, O'Neill GK, Parke R, Parker J, Rohde G, Rowan K, Turner A, Young P, Derde L, McArthur C, Webb SA. The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design. Ann Am Thorac Soc 2020;17(7):879-891 DOI: 10.1513/AnnalsATS.202003-192SD Boettler T, Newsome PN, Mondelli MU, Maticic M, Cordero E, Cornberg M, Berg T. Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper. JHEP Rep 2020;2(3):100113 DOI: 10.1016/j.jhepr.2020.100113 Nicin L, Abplanalp WT, Mellentin H, Kattih B, Tombor L, John D, Schmitto JD, Heineke J, Emrich F, Arsalan M, Holubec T, Walther T, Zeiher AM, Dimmeler S. Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts. Eur Heart J 2020;41(19):1804-1806 DOI: 10.1093/eurheartj/ehaa311 Hrusak O, Kalina T, Wolf J, Balduzzi A, Provenzi M, Rizzari C, Rives S, Del Pozo Carlavilla M, Alonso MEV, Dominguez-Pinilla N, Bourquin JP, Schmiegelow K, Attarbaschi A, Grillner P, Mellgren K, van der Werff Ten Bosch,J., Pieters R, Brozou T, Borkhardt A, Escherich G, Lauten M, Stanulla M, Smith O, Yeoh AEJ, Elitzur S, Vora A, Li CK, Ariffin H, Kolenova A, Dallapozza L, Farah R, Lazic J, Manabe A, Styczynski J, Kovacs G, Ottoffy G, Felice MS, Buldini B, Conter V, Stary J, Schrappe M. Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment. Eur J Cancer 2020;132:11-16 DOI: S0959-8049(20)30162-3 Gaborit BJ, Bergmann JF, Mussini C, Arribas JR, Behrens G, Walmsley S, Pozniak A, Raffi F. Plea for multitargeted interventions for severe COVID-19. Lancet Infect Dis 2020;20(10):1122-1123 DOI: S1473-3099(20)30312-1 Koch T, Dahlke C, Fathi A, Kupke A, Krahling V, Okba NMA, Halwe S, Rohde C, Eickmann M, Volz A, Hesterkamp T, Jambrecina A, Borregaard S, Ly ML, Zinser ME, Bartels E, Poetsch JSH, Neumann R, Fux R, Schmiedel S, Lohse AW, Haagmans BL, Sutter G, Becker S, Addo MM. Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial. Lancet Infect Dis 2020;20(7):827-838 DOI: S1473-3099(20)30248-6 Teoh JYC, Roupret M, Shariat SF, Herrmann T. Intravesical therapy for bladder cancer in the pandemic of Covid-19. World J Urol 2020 DOI: 10.1007/s00345-020-03218-8 Gross S, Jahn C, Cushman S, Bar C, Thum T. SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications. J Mol Cell Cardiol 2020;144:47-53 DOI: S0022-2828(20)30121-8 Klimek L, Pfaar O, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mosges R, Saloga J, Staubach P, Poethig D, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mulleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wohrl S, Niederberger-Leppin V, Pali-Scholl I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C, Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Bousquet J, Zuberbier T, Vogelberg C, Gerstlauer M. Allergen-Immuntherapie in der aktuellen Covid-19-Pandemie. Allergo J 2020;29(3):17-25 DOI: 10.1007/s15007-020-2539-9 Thum T. SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure? Eur Heart J 2020;41(19):1807-1809 DOI: 10.1093/eurheartj/ehaa410 Limbourg FP. Hypertension and RAAS inhibition in times of COVID-19 - current recommendations of the European Society of Hypertension. MMW Fortschr Med 2020;162(9):67-69 DOI: 10.1007/s15006-020-0483-y Gosch M, Zeeh J, Feddersen B, Michels G, Halek M, Bleckwenn M, Hauner H, Grabenhorst U, von Freyburg A, Limbourg F. MMW Fortschr Med 2020;162(9):5-020-0452-5 DOI: 10.1007/s15006-020-0452-5 Marlais M, Wlodkowski T, Vivarelli M, Pape L, Tonshoff B, Schaefer F, Tullus K. The severity of COVID-19 in children on immunosuppressive medication. Lancet Child Adolesc Health 2020;4(7):e17-e18 DOI: S2352-4642(20)30145-0 Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, Vanstapel A, Werlein C, Stark H, Tzankov A, Li WW, Li VW, Mentzer SJ, Jonigk D. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N Engl J Med 2020;383(2):120-128 DOI: 10.1056/NEJMoa2015432 Napp LC, Bauersachs J. Extracorporeal Hemoadsorption: An Option for COVID-19-Associated Cytokine Storm Syndrome. Shock 2020;54(5):700-701 DOI: 10.1097/SHK.0000000000001568 Vogel-Claussen J, Ley-Zaporozhan J, Agarwal P, Biederer J, Kauczor HU, Ley S, Kuhl H, Mueller-Lisse UG, Persigehl T, Schlett CL, Wormanns D, Antoch G, Hamer OW. Recommendations of the Thoracic Imaging Section of the German Radiological Society for clinical application of chest imaging and structured CT reporting in the COVID-19 pandemic. Rofo 2020;192(7):633-640 DOI: 10.1055/a-1174-8378 Mariani S, Hanke JS, Dogan G, Schmitto JD. Out of hospital management of LVAD patients during COVID-19 outbreak. Artif Organs 2020;44(8):873-876 DOI: 10.1111/aor.13744 Winkler AS, Knauss S, Schmutzhard E, Leonardi M, Padovani A, Abd-Allah F, Charway-Felli A, Emmrich JV, Umapathi T, Satishchandra P, Hoo FK, Dalmau J, Oreja-Guevara C, Ferreira MLB, Pfausler B, Michael BD, Tagliavini F, Hoglinger G, Endres M, Klein C, Hemmer B, Carroll W, Sejvar J, Solomon T. A call for a global COVID-19 Neuro Research Coalition. Lancet Neurol 2020;19(6):482-484 DOI: S1474-4422(20)30150-2 Mohn N, Pul R, Kleinschnitz C, Pruss H, Witte T, Stangel M, Skripuletz T. Implications of COVID-19 Outbreak on Immune Therapies in Multiple Sclerosis Patients-Lessons Learned From SARS and MERS. Front Immunol 2020;11:1059 DOI: 10.3389/fimmu.2020.01059 Seifert J, Heck J, Eckermann G, Singer M, Bleich S, Grohmann R, Toto S. Psychopharmacotherapy during the COVID-19 pandemic. Nervenarzt 2020;91(7):604-610 DOI: 10.1007/s00115-020-00939-4 Mohn N, Saker F, Bonda V, Respondek G, Bachmann M, Stoll M, Wattjes MP, Stangel M, Skripuletz T. Mild COVID-19 symptoms despite treatment with teriflunomide and high-dose methylprednisolone due to multiple sclerosis relapse. J Neurol 2020;267(10):2803-2805 DOI: 10.1007/s00415-020-09921-1 Anker SD, Butler J, Khan MS, Abraham WT, Bauersachs J, Bocchi E, Bozkurt B, Braunwald E, Chopra VK, Cleland JG, Ezekowitz J, Filippatos G, Friede T, Hernandez AF, Lam CSP, Lindenfeld J, McMurray JJV, Mehra M, Metra M, Packer M, Pieske B, Pocock SJ, Ponikowski P, Rosano GMC, Teerlink JR, Tsutsui H, Van Veldhuisen DJ, Verma S, Voors AA, Wittes J, Zannad F, Zhang J, Seferovic P, Coats AJS. Conducting clinical trials in heart failure during (and after) the COVID-19 pandemic: an Expert Consensus Position Paper from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur Heart J 2020;41(22):2109-2117 DOI: 10.1093/eurheartj/ehaa461 Behrens GMN, Cossmann A, Stankov MV, Witte T, Ernst D, Happle C, Jablonka A. Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals. Infection 2020;48(4):631-634 DOI: 10.1007/s15010-020-01461-0 Ehrenreich H, Weissenborn K, Begemann M, Busch M, Vieta E, Miskowiak KW. Erythropoietin as candidate for supportive treatment of severe COVID-19. Mol Med 2020;26(1):58-020-00186-y DOI: 10.1186/s10020-020-00186-y Klimek L, Pfaar O, Worm M, Eiwegger T, Hagemann J, Ollert M, Untersmayr E, Hoffmann-Sommergruber K, Vultaggio A, Agache I, Bavbek S, Bossios A, Casper I, Chan S, Chatzipetrou A, Vogelberg C, Firinu D, Kauppi P, Kolios A, Kothari A, Matucci A, Palomares O, Szepfalusi Z, Pohl W, Hotzenecker W, Rosenkranz A, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mosges R, Saloga J, Staubach P, Jappe U, Rabe C, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Freudelsperger L, Mulleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink Wagner A, Horak F, Wohrl S, Niederberger-Leppin V, Pali-Scholl I, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Matricardi PM, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Idzko M, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Jensen-Jarolim E, Korn S, Hentges F, Schwarze J, O Mahony L, Knol E, Del Giacco S, Chivato T, Bousquet J, Zuberbier T, Akdis C, Jutel M. Anwendung von Biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen Covid-19-Pandemie a, b, c: Positionspapier des Ärzteverbands Deutscher Allergologen (AeDA)A, der Deutschen Gesellschaft für Allergologie und klinische Immunologie (DGAKI)B, der Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, der Österreichischen Gesellschaft für Allergologie und Immunologie (ÖGAI)D, der Luxemburgischen Gesellschaft für Allergologie und Immunologie (LGAI)E, der Österreichischen Gesellschaft für Pneumologie (ÖGP)F in Kooperation mit der deutschen, österreichischen, und schweizerischen ARIA-GruppeG und der Europäischen Akademie für Allergologie und Klinische Immunologie (EAACI)H Allergo J 2020;29(4):14-27 DOI: 10.1007/s15007-020-2553-y Dowsett M, Ellis MJ, Dixon JM, Gluz O, Robertson J, Kates R, Suman VJ, Turnbull AK, Nitz U, Christgen M, Kreipe H, Kuemmel S, Bliss JM, Barry P, Johnston SR, Jacobs SA, Ma CX, Smith IE, Harbeck N. Evidence-based guidelines for managing patients with primary ER+ HER2- breast cancer deferred from surgery due to the COVID-19 pandemic. NPJ Breast Cancer 2020;6:21-020-0168-9. eCollection 2020 DOI: 10.1038/s41523-020-0168-9 Stahl K, Bode C, David S. First do no harm-beware the risk of therapeutic plasma exchange in severe COVID-19. Crit Care 2020;24(1):363-020-03070-7 DOI: 10.1186/s13054-020-03070-7 Krettek C, Mittlmeier T, Mutschler W. COVID-19 pandemic: what do we know-what can we recommend? : Comments from the editors. Unfallchirurg 2020;123(7):579-020-00832-4 DOI: 10.1007/s00113-020-00832-4 Seffer MT, Martens-Lobenhoffer J, Schmidt JJ, Eden G, Bode-Boger SM, Kielstein JT. Clearance of chloroquine and hydroxychloroquine by the Seraph(R) 100 Microbind(R) Affinity blood filter - approved for the treatment of COVID-19 patients. Ther Apher Dial 2020 DOI: 10.1111/1744-9987.13549 Sipido KR, Antonanzas F, Celis J, Degos L, Frackowiak R, Fuster V, Ganten D, Gay S, Hofstraat H, Holgate ST, Krestin G, Manns M, Meunier F, Oertel W, Palkonen S, Pavalkis D, Rubsamen-Schaeff H, Smith U, Stallknecht BM, Zima T. Overcoming fragmentation of health research in Europe: lessons from COVID-19. Lancet 2020;395(10242):1970-1971 DOI: S0140-6736(20)31411-2 Pfeifer M, Ewig S, Voshaar T, Randerath WJ, Bauer T, Geiseler J, Dellweg D, Westhoff M, Windisch W, Schonhofer B, Kluge S, Lepper PM. Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19. Respiration 2020;99(6):521-542 DOI: 10.1159/000509104 Klimek L, Pfaar O, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mosges R, Saloga J, Staubach P, Stute P, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mulleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wohrl S, Niederberger-Leppin V, Pali-Scholl I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C, Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertin F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Gerstlauer M, Vogelberg C, Bousquet J, Zuberbier T. Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA Group(A) in cooperation with the Austrian ARIA Group(B), the Swiss ARIA Group(C), German Society for Applied Allergology (AEDA)(D), German Society for Allergology and Clinical Immunology (DGAKI)(E), Society for Pediatric Allergology (GPA)(F) in cooperation with AG Clinical Immunology, Allergology and Environmental Medicine of the DGHNO-KHC(G) and the European Academy of Allergy and Clinical Immunology (EAACI)(H). Allergol Select 2020;4:44-52 DOI: 10.5414/ALX02147E Wagener FADTG, Pickkers P, Peterson SJ, Immenschuh S, Abraham NG. Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections. Antioxidants (Basel) 2020;9(6):10.3390/antiox9060540 DOI: E540 [pii] Kahl KG, Correll CU. Management of Patients With Severe Mental Illness During the Coronavirus Disease 2019 Pandemic. JAMA Psychiatry 2020;77(9):977-978 DOI: 10.1001/jamapsychiatry.2020.1701 Schmidt SB, Gruter L, Boltzmann M, Rollnik JD. Prevalence of serum IgG antibodies against SARS-CoV-2 among clinic staff. PLoS One 2020;15(6):e0235417 DOI: 10.1371/journal.pone.0235417 Polak WG, Fondevila C, Karam V, Adam R, Baumann U, Germani G, Nadalin S, Taimr P, Toso C, Troisi RI, Zieniewicz K, Belli LS, Duvoux C. Impact of COVID-19 on liver transplantation in Europe: alert from an early survey of European Liver and Intestine Transplantation Association and European Liver Transplant Registry. Transpl Int 2020 DOI: 10.1111/tri.13680 Panning M, Wiener J, Rothe K, Schneider J, Pletz MW, Rohde G, Rupp J, Witzenrath M, Spinner CD, Members of the CAPNETZ study group. No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in March 2020. Infection 2020 DOI: 10.1007/s15010-020-01471-y Tzankov A, Jonigk D. Unlocking the lockdown of science and demystifying COVID-19: how autopsies contribute to our understanding of a deadly pandemic. Virchows Arch 2020;477(3):331-333 DOI: 10.1007/s00428-020-02887-5 Odak I, Barros-Martins J, Bosnjak B, Stahl K, David S, Wiesner O, Busch M, Hoeper MM, Pink I, Welte T, Cornberg M, Stoll M, Goudeva L, Blasczyk R, Ganser A, Prinz I, Forster R, Koenecke C, Schultze-Florey CR. Reappearance of effector T cells is associated with recovery from COVID-19. EBioMedicine 2020;57:102885 DOI: S2352-3964(20)30260-7 Scholz KH, Lengenfelder B, Thilo C, Jeron A, Stefanow S, Janssens U, Bauersachs J, Schulze PC, Winter KD, Schroder J, Vom Dahl J, von Beckerath N, Seidl K, Friede T, Meyer T. Impact of COVID-19 outbreak on regional STEMI care in Germany. Clin Res Cardiol 2020 DOI: 10.1007/s00392-020-01703-z Ackermann M, Mentzer SJ, Jonigk D. Pulmonary Vascular Pathology in Covid-19. Reply. N Engl J Med 2020;383(9):888-889 DOI: 10.1056/NEJMc2022068 Wang Y, Foo R, Thum T. Using "old" medications to fight new COVID-19: Re-purposing with a purpose. J Mol Cell Cardiol 2020;146:41-42 DOI: S0022-2828(20)30227-3 Jendrny P, Schulz C, Twele F, Meller S, von Kockritz-Blickwede M, Osterhaus ADME, Ebbers J, Pilchova V, Pink I, Welte T, Manns MP, Fathi A, Ernst C, Addo MM, Schalke E, Volk HA. Scent dog identification of samples from COVID-19 patients - a pilot study. BMC Infect Dis 2020;20(1):536-020-05281-3 DOI: 10.1186/s12879-020-05281-3 Wiesner O, Busch M, David S. Treatment of severe COVID-19 courses in intensive care medicine. Internist (Berl) 2020;61(8):804-812 DOI: 10.1007/s00108-020-00850-9 Buhl T, Beissert S, Gaffal E, Goebeler M, Hertl M, Mauch C, Reich K, Schmidt E, Schon MP, Sticherling M, Sunderkotter C, Traidl-Hoffmann C, Werfel T, Wilsman-Theis D, Worm M. COVID-19 and implications for dermatological and allergological diseases. J Dtsch Dermatol Ges 2020 DOI: 10.1111/ddg.14195 Gutenbrunner C, Stokes EK, Dreinhofer K, Monsbakken J, Clarke S, Cote P, Urseau I, Constantine D, Tardif C, Balakrishna V, Nugraha B. Why Rehabilitation must have priority during and after the COVID-19-pandemic: A position statement of the Global Rehabilitation Alliance. J Rehabil Med 2020;52(7):jrm00081-2713 DOI: 10.2340/16501977-2713 Marckmann G, Neitzke G, Schildmann J, Michalsen A, Dutzmann J, Hartog C, Jobges S, Knochel K, Michels G, Pin M, Riessen R, Rogge A, Taupitz J, Janssens U. Decisions on the allocation of intensive care resources in the context of the COVID-19 pandemic : Clinical and ethical recommendations of DIVI, DGINA, DGAI, DGIIN, DGNI, DGP, DGP and AEM. Med Klin Intensivmed Notfmed 2020 DOI: 10.1007/s00063-020-00709-9 Marckmann G, Neitzke G, Schildmann J, Michalsen A, Dutzmann J, Hartog C, Jobges S, Knochel K, Michels G, Pin M, Riessen R, Rogge A, Taupitz J, Janssens U. Decisions on the allocation of intensive care resources in the context of the COVID-19 pandemic : Clinical and ethical recommendations of DIVI, DGINA, DGAI, DGIIN, DGNI, DGP, DGP and AEM. German version. Med Klin Intensivmed Notfmed 2020;115(6):477-485 DOI: 10.1007/s00063-020-00708-w Dressler D, Adib Saberi F. Botulinum toxin therapy in the SARS-CoV-2 pandemic: patient perceptions from a German cohort. J Neural Transm (Vienna) 2020;127(9):1271-1274 DOI: 10.1007/s00702-020-02235-6 Hansmann G, Bezzerides V. Paediatric/congenital cardiology physician scientists-An endangered species. Eur J Clin Invest 2020;50(10):e13367 DOI: 10.1111/eci.13367 Karagiannidis C, Mostert C, Hentschker C, Voshaar T, Malzahn J, Schillinger G, Klauber J, Janssens U, Marx G, Weber-Carstens S, Kluge S, Pfeifer M, Grabenhenrich L, Welte T, Busse R. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. Lancet Respir Med 2020;8(9):853-862 DOI: S2213-2600(20)30316-7 Salzberger B, Welte T. COVID-19-a new and many-sided challenge. Internist (Berl) 2020;61(8):773-775 DOI: 10.1007/s00108-020-00851-8 Degen C, Lenarz T, Willenborg K. Acute Profound Sensorineural Hearing Loss After COVID-19 Pneumonia. Mayo Clin Proc 2020;95(8):1801-1803 DOI: S0025-6196(20)30596-6 Yogeswaran A, Gall H, Tello K, Grunig E, Xanthouli P, Ewert R, Kamp JC, Olsson KM, Wissmuller M, Rosenkranz S, Klose H, Harbaum L, Lange TJ, Opitz CF, Waelde A, Milger K, Sommer N, Seeger W, Ghofrani HA, Richter MJ. Impact of SARS-CoV-2 pandemic on pulmonary hypertension out-patient clinics in Germany: a multi-centre study. Pulm Circ 2020;10(3):2045894020941682 DOI: 10.1177/2045894020941682 Kauczor HU, Welte T. The Role of CT in the Diagnosis of COVID-19-a State of Constant Flux. Dtsch Arztebl Int 2020;117(22-23):387-388 DOI: 10.3238/arztebl.2020.0387 Stover T, Dazert S, Hoffmann TK, Plontke SK, Ambrosch P, Arens C, Betz C, Beutner D, Bohr C, Bruchhage KL, Canis M, Dietz A, Guntinas-Lichius O, Hagen R, Hosemann W, Iro H, Klussmann JP, Knopf A, Kramer S, Lang S, Leinung M, Lenarz T, Lowenheim H, Matthias C, Mlynski R, Olze H, Park J, Plinkert P, Radeloff A, Rotter N, Rudack C, Bozzato A, Schipper J, Schrader M, Strieth S, Stuck BA, Volkenstein S, Westhofen M, Wolf G, Wollenberg B, Zahnert T, Zenk J. Effects of the SARS-CoV-2 pandemic on the otorhinolaryngology university hospitals in the field of medical care. 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