Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cells. Nat Immunol. 2025 Jul;26(7):1127-1138. doi: 10.1038/s41590-025-02182-y. Epub 2025 Jun 13. PMID: 40514418; [...] leads to an increase of granzyme-producing γδ T cells in children with congenital heart disease. Nat Commun. 2024 Nov 13;15(1):9841. doi: 10.1038/s41467-024-51673-3. PMID: 39537635. Ravens S, Tolosa E [...] after stem-cell transplantation and show adaptive clonal expansion in response to viral infection. Nat Immunol. 2017 Feb 20. doi: 10.1038/ni.3686. [Epub ahead of print] PubMed PMID: 28218745 *equal contribution

L. 2025. Structure and function relationships of mucociliary clearance in human and rat airways. Nat Commun 16, no. 1:2446. https://doi.org/10.1038/s41467-025-57667-z . van der Does, A. M., L, V. Schledorn [...] organoids recapitulate co-development of the human haematopoietic system and the embryonic heart. Nat Cell Biol 26, no. 11:1984. https://doi.org/10.1038/s41556-024-01526-4 . Finklea, F. B., Hashemi, M [...] 2024. Standardized production of hPSC-derived cardiomyocyte aggregates in stirred spinner flasks. Nat Protoc 19, no. 7:1911. https://doi.org/10.1038/s41596-024-00976-2 . Moenkemoeller, R., Budde, L., Martin

In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Nat Commun 13, 5215 (2022). Schmidt T, Meller S, Talbot SR, Berk BA, Law TH, Hobbs SL, Meyerhoff N, Packer

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vector-based DNA vaccine as a novel strategy for cancer immunotherapy. Franke, Ann-Christin (Dr. rer. nat.) Hannover Medical School, 2022 Screening chimeric GAA variants in preclinical study results in he [...] macrophages with enhanced functionality using chimeric antigen receptors. Paasch, Daniela (Dr. rer. nat. M.Sc.): Dissertation Hannover Medical School, 2021 Generation of platelets with enhanced functionality [...] transgenic proteins to alpha granules in megakaryocytes. Woods, Vanessa Mandeisa Alesia (Dr. rer. nat.) Hannover Medical School, 2021 DOI: 10.26068/mhhrpm/20210719-002 Low Energy Electron Irradiation Is

2025 Basílio-Queirós D , Lachmann N . "In vivo macrophage engineering for renal cancer therapy." Nat Cancer . 2025 Apr 29. doi: 10.1038/s43018-025-00912-7. 2024 Rodriguez Gonzalez C , Basílio-Queirós [...] Viejo-Borbolla A. "Viral modulation of type II interferon increases T cell adhesion and virus spread." Nat Commun. 2024 Jun 22;15(1):5318. doi: 10.1038/s41467-024-49657-4. Schnell A, Tamm S, Hedtfeld S, Rodriguez [...] 4744. Abdin SM , Paasch D , Lachmann N . "CAR macrophages on a fast track to solid tumor therapy" Nat Immunol . 2024 Jan;25(1):11-12. doi: 10.1038/s41590-023-01696-7. Jahn C, Juchem M, Sonnenschein K,

Lienenklaus S, Garrels W, Nazarenko I, Jonigk D, Wygrecka M, Klatt D, Schambach A, Kaminski N, Prasse A. Nat Commun 2022;13(1):5637 DOI: 10.1038/s41467-022-33193-0 2021 Generation of hiPSC-derived low threshold [...] Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N. Nat Commun. 2018 Nov 30;9(1):5088. doi: 10.1038/s41467-018-07570-7. Concise Review: Towards the Clinical [...] C, Korff T, Opalka B, Rebmann V, Göthert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4. Human monocyte-derived macrophages inhibit

Bousso P, Di Santo JP, Serafini N. Inflammation triggers ILC3 patrolling of the intestinal barrier. Nat Immunol. 2022 Aug 23. doi: 10.1038/s41590-022-01284-1. Epub ahead of print. PMID: 35999393. Bruni E [...] B, Kuball J. Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies. Nat Rev Drug Discov. 2019 Sep 6. doi: 10.1038/s41573-019-0038-z. [Epub ahead of print] Review. PubMed PMID: [...] Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells. Nat Immunol. 2018 Apr 9. doi: 10.1038/s41590-018-0082-6. [Epub ahead of print] PubMed PMID: 29632329. Ravens

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