, molecular and genetic epidemiology. Prof. Illig is the author of more than 600 peer-reviewed publications in leading journals such as Science, Nature, Nature Genetics, Plos Genetics, Lancet and the American [...] American Journal of Human Genetics. Until now, a more precise analysis of the publication activities and citations of German epidemiology was hardly possible, as the necessary data and, above all, the [...] Unified Biobank (HUB)". The MHH is one of the largest medical faculties in Germany with over 60 Institutes and more than 9,000 employees. Prof. Illig is setting up a modern high-throughput biobank at the

For laboratories working with genetically modified organisms, a similar classification into four safety levels applies according to the Genetic Engineering Act and the Genetic Engineering Safety Ordinance [...] protection to the four risk groups. Risk group 1 Biological agents that are unlikely to cause disease in humans (e.g. the safety strain Escherichia coli K12, the baker's yeast Saccharomyces cerevisiae). Group [...] that are not included in risk groups 2 to 4 Risk group 2 Biological agents that can cause illness in humans and pose a risk to employees (e.g. Salmonella spp., herpes viruses or some influenza viruses, various

Research Topic: Discovery of human genetic signatures affecting extracellular trap formation Supervisor: Dr. Volker Winstel, Pathogenesis of Bacterial Infections, Twincore & Institute of Medical Microbiology [...] colorectal cancer (CAC) Supervisor: PD Dr. Matthias Lochner, Institute for Medical Microbiology and Hospital Epidemiology, MHH Academic Background: Institute of Biomedical Sciences, University of Sao Paulo Berislav [...] Characterizing anti HCMV immunity in an infection model of explanted human lungs Supervisor: Prof. Dr. Reinhold Förster, Institute of Immunology, MHH Academic Background: Biomedicine, MHH Abdulwahab Elsayed

Oncology MHH - Clinical Department of General, Visceral and Transplant Surgery MHH - Institute of Human Genetics MHH - Tumor Center MHH - Social Services MHH - Pastoral care Cooperation partners outside [...] Haematology, Haemostaseology, Oncology and Stem Cell Transplantation MHH - Institute of Diagnostic and Interventional Radiology MHH - Institute of Pathology MHH - Clinical Department of Radiotherapy and Special [...] Dr. Heuft* Duty Doctor* Developmental diagnostics or SPC (c,d) Dr. H. Langen* Dr. A. Schmidt* Human Genetics (c,d) Dr. C. Scholz** Dr. Bernt Schulze* Internal Medicine (b) Nephro./Dialysis: Dr. A. Bertram*

key safety aspects, a genetic integrity pipeline will be generated for defining the most sensitive assays for rigorous assessment of cells’ genetic stability. Moreover, a genetic rescue tool in the form [...] with more than six million euros, of which the Medical School Hannover (MHH) is the coordinating institution. The international research team led by Dr. Robert Zweigerdt and Prof. Dr. Ulrich Martin from MHH [...] the network is establishing new tools and expertise for accelerating the development of advanced human induced pluripotent stem cell (iPSC)-based therapies. The project also aims for overcoming scientific

cleanroom conditions. This is done at the MHH at the Institute for Cell Therapeutics, in the Cellular Therapy Centre (CTC) department. But the institute offers more than manufacturing and quality control [...] time-lapse video. A look into the microscope, for example, shows whether human T cells such as CARs and TRUCKs, which have been genetically modified in the laboratory, actually recognize tumor cells better and [...] fight against the most severe diseases. In addition to stem cell transplantation, therapies using genetically modified cells have now also been approved in Europe as so-called advanced therapy medicinal products

Gausemeier/ S. Müller-Wille/ E. Ramsden, Human Heredity in the Twentieth Century , London: Pickering & Chatto, 2013, S. 13-26 „Erwin Baur“, Brenner’s Encyclopedia of Genetics (2. Aufl.), Vol. 1, Amsterdam u.a [...] a.: Elsevier, 2013, S. 304-306 Genetics as a Modernization Program: Biological Research at the Kaiser Wilhelm Institutes and the Political Economy of the Nazi State, Historical Studies in the Natural Sciences [...] 1933-1945 , Göttingen: Wallstein, 2005 Edited volumes with Staffan Müller-Wille & Edmund Ramsden: Human Heredity in the Twentieth Century , London: Pickering & Chatto, 2013 with Safia Azzouni, Christina

from the human heart, especially concerning the beating rate. Compared to the human heart, the beating frequency is about 5-8 times higher in the rodent model. Thus, a functional integration of human CMs into [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Cebotari, Martin; DPZ, ITEM): Transplantation of genetically enriched human iPSC (hiPSC) derived cardiomyocytes (CMs) in a preclinical model of heart repair (non-human primate) Subproject 2 (MHH: Köhl, Martin;

publications also in leading journals such as Science, Nature, Nature Genetics, Plos Genetics, Lancet and the American Journal of Human Genetics. Education 2010 Adjunct professor at Ludwig Maximilians-University [...] at Helmholtz Zentrum München Reviewer (selected journals) Nature Genetics, American Journal of Human Genetics, Circulation, PLOS Genetics, Experimental Dermatology, Allergy, Clinical and Experimental Allergy [...] iobanking-Genomics” in the Institute of Epidemiology Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 1998 - 2001 PostDoc, Institute of Epidemiology, Helmholtz Zentrum

the research group "Systems Biology of Microbial Communities" at the Institute of Molecular Bacteriology of TWINCORE. Significant genetic differences between harmless and dangerous bacteria The team examined [...] Escherichia coli bacteria live in the intestines of humans and play an important role there for normal intestinal function as well as for a functioning immune system. These intestinal inhabitants do not [...] Marco Galardinis team has studied this in more detail and found that E. coli has a significant genetic variation that contributes to the transition between the harmless life in the intestine (commensalism)