Viktor, U. Keilholz, A. Boehm, O. Guntinas-Lichius, B. Hennemann, H. J. Schmoll, P. Ivanyi, M. Abbas, U. Lehmann, A. Koch , A. Karch, A. Zörner, and T. C. Gauler. 2015. “TEMHEAD: A Single-Arm Multicentre [...] Düsseldorf. Koch A , Hörmann A, Löwel H, Senges J (1998): "The 60-Minutes-Myocardial Infarction Project": comparison with a registry and a randomized clinical trial. In: Abel U und Koch A (Eds.): Nonrandomized [...] Medicine 114:27–37. doi: 10.1016/j.rmed.2016.03.008. Wacker, M. E., R. A. Jörres, H. Schulz, J. Heinrich, S. Karrasch, A. Karch, A. Koch , A. Peters, R. Leidl, C. Vogelmeier, and R. Holle. 2016. “Direct and

Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V , Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Generation [...] 39. doi: 10.1038/s41522-022-00294-z. Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de la Torre RA [...] Bähre H , Geffers R, Seifert R , Møller JE, Wende AR, Bauersachs J, Schäfer A. miRNA-200b-A Potential Biomarker Identified in a Porcine Model of Cardiogenic Shock and Mechanical Unloading. Front Cardiovasc

Aldo-MR pathway filling-in these knowledge gaps. After performing a high-throughput miRNA screen, the team came across microRNA-181a (miR-181a) as a potential regulator of Aldo-MR pathway. Using special animal [...] therapeutically active compounds. However, searching for a suitable agent against a certain disease often resembles the proverbial search for a needle in a haystack. Now, an international research team from [...] DGK funds a new research project IMTTS scientist Dr. Hannah Hunkler received a 49,940 € grant for her research project “Specific degradation of Rho kinases by proximity-inducing drugs as a therapeutic

Conducted a systematic review and developed an inpatient-specific risk score using a large database of discharge summary reports, which outperformed existing administrative data in China, and built a comprehensive [...] Hosseiniasl, S. M., Felgendreff, L., Amiot, B., Minshew, A., Ahmadzada, B., Qu, Z ., ... & Cook, C. Comprehensive analysis of brain injury parameters in a preclinical porcine model of acute liver failure. Frontiers [...] deceased organ donation rates in OECD countries: a panel data analysis. BMJ open 2024; 14: e077765. Qu, Z. (2024). Interpreting COVID-19 data from China: a call for caution. The Lancet, 403(10422), 144.

breast pathology.] Pathologe 2006: 27(5): 317-8 Kumpers P, Herrmann A, Lotz J, Mengel M, Schwarz A: A blue kidney-chronic renal failure as a consequence of siderosis in paroxysmal nocturnal hemoglobinuria [...] 1139-43 Athanassiadi K, Grothusen C, Mengel M, Haverich A: Primary leiomyosarcoma of the pulmonary artery: Is aggressive treatment justified for a long survival? J Thorac Cardiovasc Surg 2006; 132(2): 435-6 [...] R, Schorn K, Menzel C, Budde P, Schulz-Knappe P, Lamping N, Pich A, Kreipe HH, Tammen H: Peptidomic analysis of breast cancer reveals a putative surrogate marker for estrogen receptor-negative carcinomas

botulinum neurotoxin A substrate binding pockets and their re-engineering for human SNAP-23. J Mol Biol 428 , 372-384. PubMed-Link Pirazzini M, Henke T, Rossetto O, Mahrhold S, Krez N, Rummel A, Montecucco C [...] PubMed-Link Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T (2013): Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 [...] Immunol 364 , 139-157. Review PubMed-Link Strotmeier J, Willjes G, Binz T, Rummel A (2012): Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage

nlm.nih.gov/pubmed/37794589 Pekayvaz K, Leunig A, Kaiser R, Joppich M, Brambs S, Janjic A, Popp O, Nixdorf D, Fumagalli V, Schmidt N , Polewka V, Anjum A, Knottenberg V, Eivers L, Wange LE, Gold C, Kirchner [...] Gabel A, Zielinski S, Keshishian H, Lareau CA, Zimmermann L, Makroczyova J, Pearce C, Krey K, Hennig T, Stegmaier S, Moyon L, Horlacher M, Werner S, Aydin J, Olguin-Nava M, Potabattula R, Kibe A, Dolken [...] Dolken L, Smyth RP, Caliskan N, Marsico A, Krempl C, Bodem J, Pichlmair A, Carr SA, Chlanda P, Erhard F, Munschauer M. SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

bleeding of nodular hyperplasia as a rare cause of acute abdomen. Chirurg 2001; 72(10): 1201-4 Benten D, Widjaja A, von Depka M, Flemming P, Trautwein C, Boker K, Vogel A, Rosenau J, Manns MP: Autoimmune [...] biopsies. Anal Biochem 2001; 295(1): 116-7 Braune C, Widjaja A, Bartels M, Bleck JS, Flemming P, Manns MP, Klempnauer J, Gebel M: Surgical removal of a distinct subcutaneous metastasis of multilocular hepatocellular [...] progression to invasiveness. Lab Invest 2001; 81(4): 565-71 Goke MN, Leppert A, Flemming P, Soudah B, Bange FC, Bleck JS, Widjaja A, Hogemann B, Mellmann J, Ockenga J, Schedel I, Gebel M, Manns MP: Intestinal

3. doi:10.1210/jc.2019-00411. K. Chobanyan-Jürgens x , R.J. Scheibe x , A.B. Potthast, M. Hein, A. Smith, R. Freund, U. Tegtbur, A.M. Das, S. Engeli, J. Jordan, S. Haufe. Influences of Hypoxia Exercise [...] (2016) May;7(2):165-80. D. Lodka, A. Pahuja, C. Geers-Knörr, R.J. Scheibe, M. Nowak, J. Hamati, C. Köhncke, B. Purfürst, T. Kanashova, S. Schmidt, D.J. Glass, I. Morano, A. Heuser, T. Kraft, R. Bassel-Duby [...] maintain striated-muscle structure a function. Molecular and Cellular Biology, (2013) 33:2586-602. M. Scharf, S. Neef, R. Freund, C. Geers - Knörr, M. Franz-Wachtel, A. Brandis, D. Krone, H. Schneider,

doi: 10.1016/j.stemcr.2021.08.016 Wunderlich S, Haase A, Merkert S, Jahn K, Deest M, Frieling H, Glage S, Korte W, Martens A, Kirschning A, Zeug A, Ponimaskin E, Göhring G, Ackermann M, Lachmann N, Moritz [...] arbeiten wir u.a. an der Entwicklung neuer Therapiekonzepte, bei denen alternative Ionenkanäle beeinflusst werden. Projekte im Bereich iPS Zell-basierte Krankheitsmodelle Evaluation of TMEM16A as a modifier [...] CFTR mutation are mostly lacking. Previous studies have suggested that a co-expressed chloride channel known as TMEM16A may serve as a novel target in therapy of CF lung disease of all CF patients. However