from a patient's symptoms down to the specific molecular mechanisms involved. Mutations in the actin genes ACTB and ACTG1 can result in developmental disorders and organ malformations collectively referred

eine erbliche Motoneuronerkrankung, hervorgerufen durch Mutationen im SMN (survival of motoneuron) Gen. Durch Verlust motorischer Nervenzellen im Rückenmark kommt es zu einer fortschreitenden Abnahme der

chronisch entzündlichen ebenso wie angeborene Krankheiten betreffen und darüber hinau s. Zell- und Gen-basierte Therapien, die von der Transplantation von klassischen blutbildenden oder mesenchymalen S

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childhood myelodysplastic syndromes--challenge for the detection of chromosomal imbalances by array-CGH. Genes Chromosomes Cancer. 2010 Oct;49(10):885-900. Greten TF, Ormandy LA, Fikuart A , Höchst B, Henschen [...] stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis, Genes Dev. 2010 Aug 1;24(15):1659-72 Stankov MV1, El Khatib M1, Thakur BK, Heitmann K , Panayotova-Dimitrova [...] Bernateck M, Tran AT, Holm L, Volkmann L, Buers D, Karst M, Stuhrmann M. Catechol-O-methyltransferase gene polymorphisms are not associated with multisomatoform disorder in a group of German multisomatoform

p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes. Lab Invest 2012; 92(11): 1635-47 Christians A, Hartmann C , Benner A, Meyer J, von Deimling A, Weller [...] Schmidt M, Prinzler J, Kerjaschki D, Sinn BV, Müller BM, Filipits M, Petry C, Dietel M: Decentral gene expression analysis for ER+/Her2- breast cancer: results of a proficiency testing program for the [...] bioassay. PLoS One 2012; 7(2): e30432 Hunecke D, Spanel R, Länger F , Nam SW, Borlak J: MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer. J Pathol 2012;

Kreipe H, Stuhrmann M: Juvenile hemochromatosis due to homozygosity for the G320V mutation in the HJV gene with fatal outcome. Clin Genet 2009; 76(5): 493-5 Chevillotte M, Landwehr S, Linta L, Frascaroli G [...] remission after decitabine treatment in a patient with secondary AML harbouring high p15 ( INK4b) gene methylation and high global DNA methylation. Ann Hematol 2009; 88(3): 275-7 Leonhardt J, Kuebler JF

Ricke-Hoch M, Wende AR, Blaner WS, Abel ED, Bauersachs J, Riehle C. Vitamin A preserves cardiac energetic gene expression in a murine model of diet-induced obesity. Am J Physiol Heart Circ Physiol 2022; 323: [...] Kaever V , Wilde A. The cyanobacterial phytochrome 2 regulates the expression of motility-related genes through the second messenger cyclic di-GMP. Photochem Photobiol Sci 2020; 11:783-801 2019 Braun F [...] 784-796 Perduns R, Volk J, Plum M, Gutzki F, Kaever V , Geurtsen W. Effects of HEMA on Nrf2-related gene expression using a newly developed 3D co-culture model of the oral mucosa. Dent Mater 2019; pii:

breast cancer between metastatic sites Grote I, Poppe A, Lehmann U, Christgen M, Kreipe H, Bartels S . Genes Chromosomes Cancer. 2024 Jan;63(1):e23199. doi: 10.1002/gcc.23199. Epub 2023 Sep 6. Comparative Analyses

Petra Uta, Faramarz Matinmehr, Tianbang Wang, Theresia Kraft, Mamta Amrute-Nayak and Tim Scholz, J Gen Physiol . 2022 Oct 3;154(10):e202213149. doi: 10.1085/jgp.202213149. Epub 2022 Sep 2, PubMed Cardiac