endocytosis The pro-inflammatory cytokine IL-1 is a critical regulator of the innate immune response and the interleukin-1 (IL-1)-mediated signal transduction is a paradigm of immune signalling. IL-1 binding [...] binding, but the function of the IL-1RI internalization remained elusive. Recently, we demonstrated a critical role for the internalization of IL-1RI in the IL-1-mediated signal transduction. We also showed

zur Zirrhose bis hin zum Leberkrebs fortschreiten lassen, sind nur unzureichend bekannt und hängen u.a. mit ernährungsbedingten und genetischen Risikofaktoren zusammen. In den letzten Jahren wurden mehrere [...] domain-containing protein 3“ (PNPLA3-I148M), welche mit der fortgeschrittenen NAFLD assoziiert ist u.a. unabhängig von BMI und/oder Diabetes Status. Die genauen Pathomechanismen, die auf die 148M-Variante [...] (einer Art Fastfood Diät) zeigen, dass die 148M-Variante zu einer besonders aggressiven NAFLD führt, u.a. auch mit der Entstehung einer mikrovesikulären Steatose. Besonders interessant war jedoch die Beobachtung

available in a pre-edited version (see below). The REIGN framework consists mainly of the Discussion Paper of the same name, and of the “REIGN Toolkit”. The Discussion Paper identifies a concrete framework [...] (Use of Research Evidence to Inform Guidance regarding Normative-ethical Topics) project to develop a framework explicating the role of evidence in the development of ethics guidelines. The resulting “REIGN [...] addresses theoretical background assumptions about the use of evidence in ethics. The “Toolkit” is a brief summary of this framework with, among other things, checklists that can be used when developing

understanding the molecular mechanisms driving neurodegenerative diseases, with a central focus on Spinal Muscular Atrophy (SMA). SMA is a severe neuromuscular disorder caused by the loss or functional deficiencies [...] for RNA metabolism, motor neuron maintenance, and regulation of the actin cytoskeleton. By utilizing a combination of state-of-the-art biophysical and biochemical techniques, including TIRF-Microscopy, Confocal [...] degeneration and progressive muscular atrophy in SMA patients. Our interdisciplinary approach provides a quantitative and mechanistic framework to guide the development of novel therapeutics that stabilize

Siegel steht in drei Größen zur Verfügung. Verwendung Siegel, Größe 3: Format DIN A3 (z.B. Plakate) Siegel, Größe 2: Format DIN A4 (z.B. Broschüren, Briefbogen) Siegel, Größe 1: Format DIN lang (z.B. Flyer)

en 2025 (EFirst). DOI: 10.1055/a-2452-9723 Schwabe S, Röwer HA, Buck C, Doctor E, Schneider N, Herbst FA. Challenges of regional hospice and palliative care networks: A group discussion study with coordinators [...] Status exploration and analysis of regional hospice and palliative care networks in Germany: A protocol for a mixed-methods study. PLoS One 2023;18(6): e0286583 ( PLoS One ) Schwabe S, Röwer H, Kamandi [...] d: Ergebnisse einer Online-Befragung. Zeitschrift für Palliativmedizin 2025 (EFirst), DOI: 10.1055/a-2543-3777 Schwabe S, Röwer HAA, Herbst FA. Herausforderungen und gute Praktiken von regionalen Hospiz-

my studies at Hannover Medical School I have completed and provided evidence of a suitable previous Bachelor's degree or a comparable degree programme at Leibniz Universität Hannover or another German or [...] language proficiency). I confirm that, in deviation from the above paragraph, I am unable to present a degree, but have proven at least 150 credit points by the application deadline. I will submit the c [...] lieu of an oath that the prerequisites have been fulfilled I confirm that I have acquired and proven a previous (German or foreign) university degree suitable for the subject at the beginning of my doctoral

Berufliche Tätigkeit: 2011-2013 Praktische Tätigkeit als Psychologische Psychotherapeutin in Ausbildung (PPiA) in der psychiatrischen Tagesklinik, auf der Station für schizophrene Spektrumserkrankungen sowie auf [...] 2013-2017 Praktische Tätigkeit als Psychologische Psychotherapeutin in fortgeschrittener Ausbildung (PPiA) in der Abteilung für Neuropsychologie der Klinik für Psychiatrie und Psychotherapie der Helios Dr. [...] z für Psychotherapie der Johannes Gutenberg-Universität Mainz (Leitung: Prof. Dr. M. Witthöft, Dr. A. Benecke) 2018 Praktische Tätigkeit als Psychologische Psychotherapeutin auf der Station für affektive

students and postdocs. Hannover Medical School is the only “medical faculty” in Germany which hosts such a large number of structured doctoral programs under the roof of one graduate school: Six (MD)/PhD programs [...] programs and three StrucMed programs, unique programs for undergraduate medical students to perform a Dr.med. thesis. Our Institute is currently part of the following teaching / education activities at [...] Medicine - PhD program Regenerative Sciences StrucMed-Program [ https://www.mhh.de/hbrs/strucmed ]. A structured 9-month program for MD students. Clinical lectures, Department of Cardiology and Angiology

Dear patient, the department of Cranio-Maxillo-Facial Surgery at Hannover Medical School consists of a skilled and experienced team utilising the latest technology according to the current state of research [...] dentoalveolar surgery up to an individual maximum treatment in maxillofacial surgery. We guarantee a comprehensive and interdisciplinary care during the whole period of your treatment. During your visit [...] Nils-Claudius Gellrich Discussion of your case and further surgical planning will be conducted after a first examination. Please contact our outpatients department to arrange an appointment: Mrs. Nicole