Events
06.06.2025
Dr. Alexey Kotlyarov
"49K binding to CD45: a strategy to evade the immune surveillance?"
Building I3, Level 01, Room 2020
Start: 12:00 noon
23.05.2025
PD Dr. Renate Scheibe
"Investigating the regulation of muscle specific RING finger protein MuRF1"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
09.05.2025
Dr. Rainer Niedenthal
"What Alphafold 3 structure predictions about the MK2/Pin1 interaction tell us and what they might mean"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
04.04.2025
Dr. Thomas Binz
"Role of accessory proteins in the oral toxicity of botulinum neurotoxins"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
28.02.2025
Prof. Dr. Dr. Abel Viejo-Borbolla
"Surfaceome profiling of the HCMV RL11 protein family reveals modulators of the immune and cardiovascular systems"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
14.02.2025
Dr. Alexandra Koch
"Heterotypic epithelial-mesenchymal cell-cell interactions in a multi-lineage 3D cell culturesystem"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
31.01.2025
PD Dr. Natalia Ronkina
"Requirement of Septin7 forhematopoiesis"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
17.01.2025
Prof. Halyna Shcherbata
"Argonaute 1 Localizes to the Nucleolus and Regulates rRNA Processing and Cell Growth via snoRNAs"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
20.09.2024
Dr. Christian Ehlting
Heinrich-Heine-Universität Düsseldorf
"MK2 and MK3 control intercellular communication within the liver during PAMP-induced acute phase response and viral infection"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
26.07.2024
Prof. Dr. Christian Bär
"Multicellular human cardiac organoids as versatile tool to study cardiovascular disease in 3D"
Building I3, Level 01, Room 2020
Start: 12:00
12.07.2024
Dr. Dr. Rainer Niedenthal
A short update on the "Downregulation of MK2 dependent inflammation by acylation"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
28.06.2024
Dr. Thomas Binz
"Extended Botulinum Neurotoxin for Treatment of Chronic Pain"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
14.06.2024
Khadija Aichane
"Engineering the adenovirus E3/49K protein for potential therapeutic applications"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
31.05.2024
Dr. Alexandra Koch
"A 3D co-culture system for liver cancer: Finding the optimal medium for studies on direct cell-to-cell contacts."
Building I3, Level 01, Room 2020
Start: 12:00 noon
17.05.2024
Jan Voß
"Influence of constitutively active p38α(D176A+F327S) on MK2 signaling"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
26.04.2024 CHANGE
Mariana Tsap
"Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
23.06.2023 Attendance event
Dr. Thomas Binz
"Transforming the insoluble 16-fold mutated PTEN specific botulinum neurotoxin E into a potential biopharmaceutical"
Building I3, Level 01, Room 2020
Start: 12:00
09.06.2023 Attendance event
Dr. Andriy Yatsenko
"Learning center in Drosophila brain as a model for human neurodegeneration"
Building I3, Level 01, Room 2020
Start: 12:00
26.05.2023 Attendance event
Dr. Mark Windheim
"Potential therapeutic application of the immunomodulatory adenovirus E3/49K protein"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
05.05.2023 Face-to-face event
Prof. Dr. Dr. Christian Bär
"Telomerase as therapeutic target in cardiac protection and regeneration"
Building I3, Level 01, Room 2020
Start: 12:00 p.m.
21.04.2023 Face-to-face event and video seminar
Dr. Alexandra Koch
"Towards an easy to handle 3D co-culture system representing non-transformed liver microenvironment with hepatocellular carcinoma"
Building I3, Level 01, Room 2020 or https://jitsi.mh-hannover.de/Institutsseminar
Start: 12:00 p.m.
31.03.2023 Classroom lecture
Chanchal Chauhan
"Mechanisms of MK2-RIPK1 crosstalk in cell death signaling"
Building I3, Level 01, Room 2020
Start: 13:00 p.m.
10.03.2023 Classroom lecture
Prof`in. Dr. Halyna R. Shcherbata
"Signaling through the Dystrophin Glycoprotein Complex affects the stress-dependent transcriptome in Drosophila"
Building I3, Level 01, Room 2020
Start: 12:00 pm
15.07.2022 Attendance event
Professor Markus Seeliger, Department of Pharmacological Sciences, Stony Brook University Medical School, New York
"Kinetics of Kinase inhibitor binding and development of highly selective Cyclophilin Inhibitors"
Lecture hall B, start: 12:00 noon
08.07.2022 Attendance event
Dr. Thomas Binz
"Analysis of PTEN cleaving BoNT/E mutants as potential new pharmaceuticals"
PD Dr. Renate Scheibe
"Investigating the ageing muscle"
Lecture hall B, start: 12:00 noon
01.07.2022 Face-to-face event
Dr. Mark Windheim
"How to catch the biggest protein in the pond (and kill it)"
Lecture hall N, start: 12:00 noon
17.06.2022 Attendance event
Dr. Rainer Niedenthal
"Types of modification involved in the regulation of MK2"
Lecture hall M, start: 12:00
03.06.2022 Attendance event
Rucha Yeshwanta Hebalkar
"Stress-dependent redistribution and non-canonical functions of Drosophila Argonaute 1"
Lecture hall N, start: 12:00
13.05.2022 Attendance event
Prof. Dr. Dr. Matthias Gaestel
"MAPK-activated protein kinases - A current overview"
Lecture hall N, start: 12:00
18.06.2021 VIDEOSEMINAR
Chanchal Chauhan
"Mechanisms of MK2-RIPK1 cross-talk in cell death signaling"
Start: 12:00
04.06.2021 VIDEOSEMINAR
PD Dr. Renate Scheibe
"Regulation of protein homeostasis in striated muscle"
Start: 12:00 pm
21.05.2021 VIDEOSEMINAR
Dr. Travis D. Carney
"Tissue-Specific Regulation of Translational Readthrough Tunes Functions of the Traffic Jam Transcription Factor"
Start: 12:00 pm
07.05.2021 VIDEOSEMINAR
Dr. Alexandra Koch
"Setting up a self-organizing "liver" organoid model for studies on cell-to-cell communication between cancer cells and tumor microenvironment"
Start: 12:00 pm
23.04.2021 VIDEOSEMINAR
Ms. Mareike Polenkowski
"The novel function of THOC5, a member of transcription/export complex 1, during transcription elongation"
Start: 12:00 p.m.
09.04.2021 VIDEOSEMINAR
Dr. Thomas Binz
"Evolution of botulinum neurotoxin proteases with novel specificity"
Start: 12:00 p.m.
19.03.2021 VIDEOSEMINAR
Dr. Rainer Niedenthal
"Functional aspects of MK2 SUMOylation"
Start: 12:00 noon
05.03.2021 VIDEOSEMINAR
Dr. Mark Windheim
"The Yin and Yang of the adenoviral E3/49K protein - Taking the pieces apart"
Start: 12:00 noon
19.02.2021 VIDEOSEMINAR
Ona Marija Singh
"Roles of RNP-assembling protein Rbfox1 in stress and disease"
Start: 12:00 pm
05.02.2021 VIDEOSEMINAR
Dr. Abdulhadi Suwandi
"Sweet talk : Interplay of host glycosylation, pathogen and microbiota in the gastrointestinal tract"
Start: 12:00 p.m.
29.01.2021 VIDEOSEMINAR
Mariana Sliusarenko
"Dissecting the molecular mechanisms of neurodegeneration and protective roles of miRNAs in Drosophila SWS/NTE neuropathy model"
Start: 12:00 noon
09.10.2020 VIDEOSEMINAR
PD Dr. Renate Scheibe
"Investigating the regulation of muscle specific RING finger protein MuRF1 - An E3 ligase in striated muscle"
Start: 12:00 p.m.
11.09.2020 VIDEOSEMINAR
Sebastian Rodrigo Burbano De Lara Carillo
"Long noncoding RNAs: A source of cancer specific "hidden" peptides in hepatocellular carcinoma"
Start: 12:00 p.m.
10.07.2020 VIDEOSEMINAR
Dr. Thomas Binz
"Application of SNARE stapling method for selective and enhanced delivery of botulinum protease domain to target cells"
Start: 12:00
19.06.2020 VIDEOSEMINAR
Dr. Rainer Niedenthal
"Modulating the MAPKAPK2 Signal transduction - an update"
Start: 12:00
13.03.2020 CANCELLED
Dr. Rainer Niedenthal
"Modulating the MAPKAPK2 Signal transduction - an update"
14.02.2020
Dr. Mark Windheim
"Characterization of the interaction between the adenoviral immunomodulator E3/49K and the tyrosine phosphatase CD45"
Building I3, Level 01, R.-No. 2020, 12.00 noon
31.01.2020
Dr. Travis D. Carney
"MicroRNA-317 in testis and germline development in Drosophila"
Building I3, Level 01, Room no. 2020, 12.00 h
17.01.2020
Dr. Sarah Maria Irmscher
"The role of MAPKAP kinases in sterile inflammation"
Building I3, Level 01, Room no. 2020, 12.00 h
07.06.2019
Dr. Claudia Pokoyski
"Modulation of human immune cell responses in xenotransplantation"
Building I3, Level 01, R.No. 2020, 12.00 h
10.05.2019
Dr. Rainer Niedenthal
"Modulating the MAPKAPK2 dependent Signal Transduction"
Building I3, Level 01, R.-No. 2020, 12.00 h
26.04.2019
Dr. Robert Freund
"New insights in skeletal muscle signaling"
Building I3, Level 01, R.-Nr. 2020, 12.00 h
12.04.2019
Dr. Oliver Dittrich-Breiholz
"Two years of Research Core Unit Genomics at the MHH - provided services and recent developments, e.g. single cell RNA-Seq"
Building I3, Level 01, R.-No. 2020, 12.00 h
29.03.2019
Dr. Doan Duy Hai Tran
"Application of third generation sequencing (Nanopore Sequencing Technology): Identification of sorafenib resistance mechanisms in hepatocellular carcinoma"
Building I3, Level 01, R.-No. 2020, 12.00 h
15.03.2019
Shruti Chhetri, PhD candidate (AG Shcherbata)
"Role of miR-137 in muscular dystrophy in Drosophila"
Building I3, Level 01, R.-No. 2020, 12.00 h
22.02.2019
Dr. Thomas Binz
"Mutations in light chain of botulinum neurotoxin A enable cleavage of human SNAP-23"
Building I3, Level 01, R.-No. 2020, 12.00 p.m.
01.02.2019
PD Manoj B. Menon, Ph.D.
"Cell-type specificity of septin function: further evidence from the immune system"
Building I3, Level 01, R.-No. 2020, 12.00 p.m.
11.01.2019
Dr. Andriy Yatsenko
"Notch, steroids and miRNA carve out a perfect ovary"
Building I3, Level 01, R.-No. 2020, 12.00 noon
03.12.2018
Sonia A.L. Correa, PhD
University of Bradford, UK
"Arc/Arg3.1 as a major coordinator of cognition"
Building I3, Level 01, R.-No. 2020, 12.00 noon
19.07.2018
Prof. Tadashi Yamamoto
Okinawa Institute of Science and Technology (OIST), Cell Signal Unit
"Physiology of the mRNA poly(A) tail"
Building I3, Level 01, R.-Nr. 2020, 12.00 h
22.06.2018
Dr. Robert Freund
"New insights in skeletal muscle signaling"
Building I3, Level 01, R.-No. 2020, 12.00 h
04.06.2018
Dr. Mark Windheim
"Is the protein tyrosine phosphatase CD45 a hub for viral immunomodulation?
Gebäude I3, Ebene 01, R.-Nr. 2020, 12.00 Uhr
25.05.2018
Prof. Dr. Teruko Tamura-Niemann
"The transcription/Export complex TREX and cell growth"
Gebäude I3, Ebene 01, R.-Nr. 2020, 12.00 Uhr
04.05.2018
Dr. Thomas Binz
"Emerging variety of botulinum neurotoxins"
Gebäude I3, Ebene 01, R.-Nr. 2020, 12.00 h
20.04.2018
Dr. Natalia Ronkina
"Generation and initial characterization of ERK3 (Mapk6) conditional knockout mouse"
Building I3, Level 01, R.-No. 2020, 12.00 h
02.02.2018
Dr. Rainer Niedenthal
"A potential difference in the regulation of MK2 and MK3"
Building I3, Level 01, R.-.No. 2020, 12.00 h
15.12.2017
Dr. Mark Windheim
"The Adenovirus 19a E3/49K Protein: A Christmas Update"
Building I3, Level 01, R.-No. 2020, 12.00 noon
08.12.2017
Dr. Robert Freund
"Investigating X1 - a MK2 substrate in striated muscle"
Prof. Dr. Matthias Preller
"Biophysical methods to study interactions and structure"
Building I3, Level 01, R.-No. 2020, 12.00 p.m.
17.11.2017
Dr. Thomas Binz
"A BoNT/C mutant with altered biological properties as possible new therapeutic"
Building I3, Level 01, R.-Nr. 2020, 12.00 h
03.11.2017
Prof. Dr. Teruko Tamura-Niemann
"Seeking "hidden peptides" in cancer cells"
Building I3, Level 01, R.-No. 2020, 12.00 h
20.10.2017
Dr. Manoj B. Menon
"To die or not to die: MK2 makes the final call on RIPK1-dependent death"
Building I3, Level 01, R.-No. 2020, 12.00 h
28.07.2017
Dr. Rainer Niedenthal
"Interactions of phosphorylations of MK2"
Building I3, Level 01, R.-.No. 2020, 12.00 h
14.07.2017
Dr. Mark Windheim
"Lessons from adenoviruses: How secreted and cell surface-expressed viral proteins modulate the immune response"
Building I3, Level 01, R.-.No. 2020, 12.00 h
07.07.2017
Dr. Robert Freund
"Generation of CRISPR/Cas9-mediated NFATc KOs in C2C12 myoblasts: -from troubleshooting to success-"
Building I3, Level 01, R.-.No. 2020, 12.00 noon
30.06.2017
Dr. Doan Duy Hai Tran
"Epigenetic reprogramming during liver regeneration and hepatocellular carcinoma formation: application of third generation sequencing technology"
Building I3, Level 01, R.-.No. 2020, 12.00 noon
16.06.2017
Delf-Magnus Kummerfeld
"The Challenge of Building a Better BoNT"
Building I3, Level 01, R.-Nr. 2020, 12.00 h
02.06.2017
Marcus Vauth
"MK3 as a disease causing kinase"
Building I3, Level 01, R.-No. 2020, 12.00 h
19.05.2017
Philipp Trulley
"Alternative translation of MK2
Same same - but different - but still same?"
Building I3, Level 01, R.-No. 2020, 12.00 noon
10.02.2017
Dr. Rainer Niedenthal
"MAPKAPK2 phosphorylation and the aggresome"
Building I3, Level 01, R.-Nr. 2020, 12.00 h
27.01.2017
Dr. Oliver Dittrich-Breiholz
"The Research Core Unit Genomics - a service unit for Microarray- and NGS-based applications"
Building I 3, Level 01, R.-No. 2020, 12.00 h
13.01.2017
Dr. Mark Windheim
"How does endosomal signalling control the interleukin-1-induced gene expression?"
Building I 3, Level 01, Room No. 2020, 12.00 noon
16.12.2016
Prof. Dr. Teruko Tamura-Niemann
"Targeting Dark Matter in Hepatocellular carcinoma"
Building I 3, Level 01, RoomNo. 2020, 13.00 (Attention: changed starting time!)
25.11.2016
Dr. Stefan Sikorra
"Generation of an effectively SNAP-23 proteolyzing botulinum neurotoxin A variant"
Building I 3, Level 01, R.-.Nr. 2020, 12.00 h
04.11.2016
Dr. Manoj Balakrishna Menon
"MK2 in cell death signaling: the RIP connection"
Building I 3, Level 01, R.-No. 2020, 12.00 h
29.07.2016
Dr. Rainer Niedenthal
"A new aspect in the phosphorylation-dependent regulation of MK2"
Building I 3, Level 01, Room no. 2020, 12.00 noon
08.07.2016
Dr. Doan Duy Hai Tran
"THOC5 dependent 3' processing is influenced by transcription elongation rate"
Building I 3, Level 01, R.-No. 2020, 12.00 h
24.06.2016
Prof. Dr. Helmut Holtmann
"A translational silencing element in the IκBζ mRNA involves MCPIP1 and acts at a post-initiation event"
Building I 3, Level 01, R.-No. 2020, 12.00 h
10.06.2016
Prof. Dr. Roland Jacobs
"Cellular Crosstalk of Human Natural Killer (NK) Cells"
Building I 3, Level 01, R.-No. 2020, 12.00 noon
27.05.2016
Dr. Stefan Sikorra
"i) Re-engineering of BoNT/A for human SNAP-23
ii) Characterization of BoNT/F subtypes"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
13.05.2016
Dr. Manuel D. Díaz-Munoz; Babraham Institute, Cambridge, UK
"Post-transcriptional mRNA regulation shapes gene expression during the B cell antibody response"
Building I 3, Level 01, R.-No. 2020, 12.00 h
22.01.2016
Dr. Robert Freund
"Investigations in skeletal muscle signalling - an update"
Building I 3, Level 01, R.-No. 2020, 12.00 h
08.01.2016
Dr. Mark Windheim
"A tale of two Proteins: The travels of a viral immunomodulator and a cytokine receptor"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
11.12.2015
Dr. Takayuki Nojima
"Catch polymerase in the NET; nascent RNA analysis at single nucleotide resolution"
Building I 3, Level 01, R.-No. 2020, 12.00 h
27.11.2015
Dr. Stefan Sikorra
"Identification of botulinum toxin mutants exhibiting increased activity to hSNAP-23 or TI-VAMP"
Building I 3, Level 01, Room no. 2020, 12.00 noon
06.11.2015
Dr. Rainer Niedenthal
"News about MK2 SUMOylation"
Building I 3, Level 01, Room no. 2020, 12.00 noon
16.10.2015
Gesine Behrens
"Functional characteristics of a translational silencing element in the mRNA of IκBζ"
Building I 3, level 01, room no. 2020, 1.00 p.m. ATTENTION: Starting time changed!
02.10.2015
Megha Abbey
"Biochemical and functional characterization of SEPT7"
Building I 3, Level 01, R.-No. 2020, 12.00
20.02.2015
Dr. Oliver Dittrich-Breiholz
"The Research Core Unit Transcriptomics - mRNA expression analyses based on Microarrays and beyond..."
Building I 3, level 01, room no. 2020, 12.00 noon
06.02.2015
Dr. Thomas Binz and Dr. Stefan Sikorra
"Botulinum toxins mutants as potential therapeutics for hypersecretion associated diseases"
Building I 3, level 01, room no. 2020, 12.00 noon
23.01.2015
Dr. Mark Windheim
"What is the role of membrane rafts in IL-1 signaling?"
Building I 3, Level 01, Room no. 2020, 12.00 noon
09.01.2015
Prof. Dr. Dr. Tamura-Niemann
"Murine precision-cut liver slices (PCLS) as potential tools for studying liver regeneration"
Building I 3, Level 01, Room no. 2020, 12.00 noon
12.12.2014
Robert Freund
"New investigations in skeletal muscle signaling"
Building I 3, Level 01, Room no. 2020, 12.00 noon
28.11.2014
Dr. Rainer Niedenthal
"New aspects of MK2 regulation"
Building I 3, Level 01, Room no. 2020, 12.00 noon
14.11.2014
Prof. Dr. Helmut Holtmann
"Investigations on an IL-1-controlled translational silencing element"
Building I 3, Level 01, Room no. 2020, 12.00 noon
31.10.2014
Dr. Christopher Tiedje
"p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting (NEXT) complex"
Building I 3, Level 01, Room no. 2020, 12.00 noon
17.10.2014
Prof. Dr. Dr. Michael Kracht
"Signaling to chromatin in cytokine pathways"
Building I 3, Level 01, Room no. 2020, BEGIN 1.00 p.m.
06.06.2014
Dr. Thomas Binz
"Structure and function of botulinum neurotoxin accessory proteins"
Building I 3, Level 01, Room no. 2020, 12.00 noon
09.05.2014
Shashank Saran
"Role of THOC5 in cell proliferation or differentiation and as a target for cancer therapy"
Building I 3, Level 01, Room no. 2020, 12.00 noon
25.04.2014
Robert Freund
"Investigation of NFATc1 function in skeletal muscle and regulation of SERCA2a in skeletal and heart muscle"
Building I 3, Level 01, Room no. 2020, 12.00 noon
28.03.2014
PD Dr. Udo Bavendiek
"MK2 and cardiovascular remodeling"
Building I 3, Level 01, Room no. 2020, 12.00 noon
28.02.2014
Dr. Rainer Niedenthal
"Effects of SUMOylation on MK2 structure and function"
Building I 3, Level 01, Room no. 2020, 12.00 noon
14.02.2014
Prof. Dr. Dr. Helmut Holtmann
"Post-transcriptional control of gene expression by IL-1 and IL-17"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
31.01.2014
Dr. Mark Windheim
"A secreted adenovirus protein binds to the leukocyte common antigen CD45 and modulates the host immune response"
Building I 3, Level 01, R.-No. 2020, 12.00 h
17.01.2014
Mohammad Tehrani
"Regulation of promoter-upstream transcripts (PROMPTs)"
Building I 3, Level 01, R.-.No. 2020, 12.00 h
06.12.2013
Dr. Nelli Shushakova, Ph.D.
"Protein kinase C-θ in inflammation: regulation of neutrophil recruitment, adhesion strengthening and pro-inflammatory mediator release"
Building I 3, Level 01, R.-No. 2020, 12.00 h
08.11.2013
Prof. Anthony D. Whetton
"The use of proteomics in biomarker discovery and leukaemia research"
Building I 3, Level 01, R.-No. 2020, 12.00 noon
21.06.2013
Prof. Dr. Dr. Thomas Thum
"Regulatory RNAs in the heart"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
31.05.2013
Prof. Dr. Vigo Heissmeyer
"Molecular control of follicular helper T cell differentiation by Roquin family proteins"
Building I 3, Level 01, R.-No. 2020, 12.00 h
24.05.2013
Dr. Christopher Tiedje
"iCLIP of TTP"
Building I 3, Level 01, R.-No. 2020, 12.00 h
03.05.2013
Prof. Dr. Faikah Güler
"Hypoxia induced renal fibrosis and protein kinase C signaling"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
19.04.2013
Dr. Alexandra Koch
"Degradation of macrophage-colony stimulating factor receptor, c-Fms, in epithelial cancer cells is enhanced by induction of autophagy"
Building I 3, Level 01, R.-No. 2020, 12.00 h
05.04.2013
Oliver Scholz
"STAT-SUMOylation, a possible regulator of JAK/STAT-signaltransduction"
Building I 3, Level 01, R.-Nr. 2020, 12.00 h
15.03.2013
Prof. Dr. Helmut Holtmann
"Diversity of post-transcriptional mechanisms activated by IL-1"
Building I 3, Level 01, R.-No. 2020, 12.00 h
01.03.2013
Dr. Mark Windheim
"Ubiquitination, endocytosis and signalling: Is there a connection?"
Building I 3, Level 01, Room No. 2020, 12.00 noon
15.02.2013
Prof. Dr. Evgeni Ponimaskin
"Regulation of neuronal morphology and synaptic plasticity via serotonin receptors"
Building I 3, Level 01, RoomNo. 2020, 12.00 h
08.02.2013
Dr. Stefan Sikorra
"Attempts towards engineered botulinum neurotoxins for novel medical applications: screening for light chain variants that cleave human SNAP23"
Building I 3, Level 01, R.-No. 2020, 12.00 h
18.01.2013
Alessandro Provenzani, Ph.D.
Centre for Integrative Biology, University of Trento, Italy
"How the RNA-binding protein HuR is involved in the drug resistance mechanism to doxorubicin"
Building I 3, Level 01, R.-No. 2020, 12.00 noon
14.12.2012
Dr. Natalia Ronkina
"Characterization of MRTF-A as a novel substrate of MK2"
Building I 3, Level 01, Room no. 2020, 12.00 noon
30.11.2012
Shashank Saran and Doan Duy Hai Tran
"THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation, thereby playing a key role in the mRNA export of immediate early genes induced by CSF-1 stimulation"
Building I 3, Level 01, Room no. 2020, 12.00 noon
16.11.2012
PhD M. Lienhard Schmitz
Institute of Biochemistry, University of Giessen
"Posttranslational modifications of protein kinases regulates outcomes and thresholds of signaling"
Building I 3, Level 01, Room no. 2020, 1.00 p.m.
09.11.2012
Erum Naqvi
"MAPKAP kinase 2 SUMOylation and the analysis of its functions in signal transduction"
Building I 3, Level 01, Room no. 2020, 12.00 noon
26.10.2012
Dr. Adrian Schwarzer
"Receptor tyrosine kinases, Notch mutations and PTEN loss converge on mTOR in acute T-lymphoblastic leukemia and cause addiction to cap-dependent mRNA translation".
Building I 3, Level 01, Room no. 2020, 12.00 noon
31.08.2012
Benjamin Hansen
"Interleukin-1 receptor signaling and endocytosis: a mechanism to control negative feedback regulation"
Building I 3, Level 01, Room no. 2020, 12.00 noon
10.08.2012
PD Dr. med. Klaus Ruckdeschel
"Reprogramming of innate immune cell function and viability by Yersinia"
Building I 3, Level 01, Room no. 2020, 12.00 noon
06.07.2012
Robert Freund
"Altered SERCA2a expression and cardiac function in MK2/3-/- mice"
Building I 3, Level 01, Room no. 2020, 12.00 noon
08.06.2012
Dr. Stefan Mahrhold
"Identification of the SV2A-binding site of Botulinum Neurotoxin
Type E"
Building I 3, Level 01, Room no. 2020, 12.00 noon
01.06.2012
Dr. Helge Ewers, ETH Zurich
"Seeing the forest, tree by tree - Investigating multiprotein complexes by single molecule localization microscopy"
Building I 3, level 01, room no. 2020, 12.00 noon
25.05.2012
PhD Manoj Balakrishna Menon
"Initial characterization of the Septin7 conditional knockout mice"
Building I 3, Level 01, Room no. 2020, 12.00 noon
23.03.2012
Björn Breyer
"Identification of cell type specific signals of the receptor tyrosine kinases c-Fms and TrkA by transcriptome analyses in epithelial cells"
Building I 3, level 01, room no. 2020, 12.00 noon
09.03.2012
Dr. Sonam Dhamija
"Activation of post-transcriptional control mechanisms by the pro-inflammatory cytokine interleukin-1"
Building I 3, Level 01, Room no. 2020, 12.00 noon
24.02.2012
Benjamin Hansen
Endocytosis and IL-1-induced gene expression: lessons from "superinduction"
Building I 3, Level 01, Room no. 2020, 12.00 noon
10.02.2012
Madeleine Scharf
"Analysis of MK2/3 deficiency in adult skeletal muscle and cell culture"
Building I 3, Level 01, Room no. 2020, 12.00 noon
27.01.2012
Dr. Rainer Niedenthal
"New SUMOylation substrates: CIN85, CD2AP and SMN"
Building I 3, Level 01, Room no. 2020, 12.00 noon
09.12.2011
Dr. Stefan Sikorra
"Limited proteolysis of hSNAP23 by Botulinum Neurotoxin A light chain - molecular basis and optimization"
Building I 3, level 01, room no. 2020, 12.00 noon
25.11.2011
Dr. Christopher Tiedje
"MK2 and TTP regulate TNFa translation at the ER membrane"
Building I 3, level 01, room no. 2020, 12.00 noon
28.10.2011
Sheetal Ramachandran
"Functional characterization of THOC5/FMIP, a member of mRNA export complex, in cell differentiation and DNA damage response"
Building I 3, Level 01, Room no. 2020, 12.00 noon
14.10.2011
Tadashi Yamamoto
"CDC7 kinase/Tob competes with DDB1-Cul4-Cdt2 E3 ligase in DNA damage-induced apoptosis"
Building I 3, Level 01, Room No. 2020, 12.00 noon
08.07.2011
Dr. Mark Windheim
"Defining the Role of Endocytosis in IL-1 Signaling"
Building I 3, Level 01, Room No. 2020, 12.00 p.m.
01.07.2011
Robert Freund
"ERK1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/β gene expression via acetylation of NFATc1"
Building I 3, level 01, room no. 2020, 12.00 noon
10.06.2011
Oliver Scholz
"SUMOylation in cytokine induced transcriptional activation of Signal Transducer and Activator of Transcription (STAT) proteins"
Building I 3, Level 01, Room no. 2020, 12.00 noon
27.05.2011
Frank Brand
"ERK3-MK5 signaling complex can regulate Septin-mediated dendritic branching and spine morphology"
Building I 3, Level 01, Room no. 2020, 12.00 noon
13.05.2011
Dr. Stefan Mahrhold
"Protein Receptors of Clostridial Neurotoxins and Identification of Their Binding Sites"
Building I 3, Level 01, Room No. 2020, 12.00 p.m.
29.04.2011
Sonam Dhamija
"Interleukin-1 activated post-transcriptional control affecting mRNA stability and translation"
Building I 3, Level 01, Room no. 2020, 12.00 noon
15.04.2011
Dr. Alexandra Koch
"Transcriptome analysis of TrkA-mediated survival and proliferation signals in the human mast cell leukemia cell line HMC-1 reveals a novel TrkA target gene: KLF2"
Building I 3, Level 01, Room No. 2020, 12.00 p.m.
04.03.2011
Madeleine Scharf
"Analysis of MK2/3 deficiency in adult skeletal muscle and cell culture"
Building I 3, level 01, room no. 2020, 12.00 noon
18.02.2011
Benjamin Hansen
"Ligand-induced receptor endocytosis regulates IL-1 signaling"
Building I 3, Level 01, Room no. 2020, 12.00 noon
14.01.2011
Dr. Christopher Tiedje
"Modulation of cytokine translation by TTP and MK2"
Building I 3, Level 01, Room no. 2020, 11.00 a.m.
03.12.2010
PD Dr. Dirk Ostareck, RWTH Aachen University
"Post-transcriptional control of protein synthesis"
Building I 3, Level 01, Room no. 2020, 12.30 p.m.
19.11.2010
Susan Schwede
"Investigations to the regulatory interplay between
SUMOylation and other protein modifications at STAT proteins and the MAPKAP-kinase 2"
Building I 3, Level 01, Room no. 2020, 12.00 p.m.
05.11.2010
Ratnesh Kumar Srivastav
"Development of the Trans-SUMOylation system for studying protein-protein interaction and analyzing the function of
Ubc9 SUMOylation"
Building I 3, Level 01, Room No. 2020, 12.00 noon
22.10.2010
Dr. Stefan Sikorra
"Reengineering of the BoNT/A, B and F catalytic domain via site-directed and random mutagenesis"
Building I 3, Level 01, Room no. 2020, 12.00 p.m.
04.06.2010
Sonam Dhamija
"Interleukin-1-induced post-transcriptional regulation of NFKBIZ (IkBz)"
Building I 4, Level 01, Room No. 1140, 12.00 p.m.
21.05.2010
Prof. Dr. Matthias Gaestel
"Biological monitoring of non-thermal effects of mobile phones: recent approaches and challenges"
Building I 4, level 01, room no. 1140, 12.00 noon
07.05.2010
Dr. Mark Windheim
"Spatial and temporal organization of interleukin-1 signaling"
Building K 6, level H0, room no. 3160, 12.00 p.m.
23.04.2010
Manoj B. Menon
"Functional characterization of the p38 MAPK- MK2/3 complex"
Building I 2, Level H0, S1/S2, R.-No. 1410, 12.00 h
09.04.2010
Dr. Oliver Dittrich-Breiholz
"Optimization of the "ChIP on chip" method
RNA-Pol-II occupancy as a read-out for transcriptional activity"
Building I 4, Level 01, Room No. 1140, 12.00 noon
19.03.2010
Dr. Niemann-Seyde, Susanne, Sheetal Ramachandran
"Roles of Fms interacting protein (FMIP)/THOC5, a member of mRNA export complex, TREX (Transcription/export) in hematopoiesis and DNA damage"
Building I 4, level 01, room no. 1140, 12.00 noon
19.02.2010
Friend, Robert
"Transcriptional regulation and posttranslational modification of factors involved in Ca2+ -dependent signaling in muscle"
Building I 4, Level 01, Room No. 1140, 12.00 noon
05.02.2010
Dr. Mahrhold, Stefan
"Identification and Characterization of Botulinum Neurotoxin Protein Receptors"
Building I 2, level H0, room no. 1410, seminar room S1/S2, 12.00 p.m.
22.01.2010
Dr. Niedenthal
"News about Trans-SUMOylation"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 noon
13.11.2009
Sonam Dhamija
"Regulation of mRNA degradation and translation by Interleukin-1"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 noon
30.10.2009
Frank Brand
"Extending the ERK3-MK5 Signaling Module by Interaction Trap and Kinase Profiling"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 p.m.
16.10.2009
Dr. Mark Windheim
"Beyond the plasma membrane: What is the role of endocytosis in interleukin-1 signaling"
Building I 2, level SO, seminar room S 6, 12.00 noon
02.10.2009
Priyanka Dutta
"Molecular mechanisms underlying nerve growth factor mediated survival of human mast cell leukemia (HMC-1) cells"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 noon
18.09.2009
Dr. Renate Scheibe
"Signaling pathways and physiology of muscle contractions in muscle fiber types"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 noon
10.07.2009
Dr. Stefan Sikorra
"Substantial studies and first results in BoNT light chain Engineering"
Building I 6, Level H, L 32, near HS R, 12.00 p.m.
03.07.2009
Susan Schwede
"Analysis of SUMOylation of STAT proteins and of the MAPKAP-kinase"
Building I 4, level 01, room no. 1140 (seminar room), 12.00 noon
05.06.2009
Dhamija, Sonam
"Control of IL-8 mRNA degradation by KSRP and TTP"
Building TH II, Level H, L 32, near HS R, 12.00 h
15.05.2009
Dr. Tiedje, Christopher
"Analysis of TNFa mRNA regulation"
Building I 4, Level 01, Room 1140, 12.00 h
20.03.2009
Dr. Dittrich-Breiholz
"Challenges with regard to microarray studies
-
Analysis of KSHV-induced mRNA expression changes in primary endothelial cells"
Building I 4, Level 01, Room 1140, 12.00 noon
27.02.2009
Manoj Menon
"Keratin 20 phosphorylation... Tissue specific role of MAPKAPK2 in the intestine"
Building I2, Level HO, Lecture Hall B
13.02.2009
Dr. Renate Scheibe
"Signaling pathways and physiology of muscle contractions in slow and fast fibers"
Building I4, Level 01, Room 1140, 12.00 noon
30.01.2009
Omar El Bounkari
"Characterization of Fms-interacting protein (FMIP): connection between receptor tyrosine kinase signaling and mRNA-processing"
Building I4, Level 01, Room 1140, 12.00 h
16.01.2009
Dr. Stefan Marhold
"Identification of Botulinum Neurotoxin Protein Receptors"
Building I4, Level 01, Room 1140, 12.00 p.m.
12.12.2008
Dr. Rainer Niedenthal
"News about Ubc9/substrate dimerization-dependent SUMOylation (USDDS and Trans-SUMOylation (TRS)"
Building I4, Level 01, Room 1140, 12.00 noon
28.11.2008
PD Dr. Wolfgang Eberhardt Johann Wolfgang Goethe University Frankfurt
"Regulation of the mRNA-binding protein HuR by protein kinase C-implications for renal inflammation and fibrosis"
Building I4, Level 01, Room 1140, 12.00 p.m.
31.10.2008
Jessica Schwermann
Experimental approaches to understand the function of MAPKAP kinase MK2 by identification and further characterization of its substrates and interacting proteins
17.10.2008
Dr. Edgar Grinstein Heinrich-Heine-University Düsseldorf
Rb-associated factor nucleolin in gene regulation and signaling: the role in somatic stem and progenitor cells
Dr. Mark Windheim LIMES Institute, University Bonn
Molecular mechanisms of ubiquitin-dependent signaling in innate immunity
Building I4, Level 01, Room 1140, 12.00 p.m.
22.09.2008
Prof. Tadashi Yamamoto
Association of the tob antiproliferative protein with the CCR4-NOT COMPLEX, a platform of deadenylase-based gene regulation
Building I2, level HO, near lecture hall E, room S1/S2, 12.00 h
05.09.2008
Prof. Stefan Ludwig University of Münster
How influenza A virus evades the IFN response
Seminar room 1330, 12.00 h
05.09.2008
Eike Hrincius Uni Münster/Hannover
Functional analysis of interactions of the influenza A-virus non structural protein 1 (NS1) with cellular factors
Seminar room 1330, 12.00 h
11.07.2008
Dr. Renate Scheibe
Muscle fiber types:
Signaling pathways and physiology of muscle contractions
Part II
Seminar room 1330, 12.00 h
04.07.2008
Ratnesh Kumar Srivastav
"Trans-SUMOylation: A new method to study protein-protein interaction in-vivo"
Seminar room 1330, 12.00 h
20.06.2008
PD Dr. Viktor Wixler
"FHL2-Between Healing and Destruction of Cartilage in Rheumatoid Arthritis"
Seminar room 1330, 12.00 h
06.06.2008
Prof. Dr. Dr. Bernhard Brenner
Molecular Motors: Observing Individual Molecules at Work by TIRF-Microscopy
Seminar room 1330, 12.00 h
09.05.2008
Dr. Alexandra Koch
Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover
Seminar room 1330, 12.00 h
25.04.2008
Prof. Dr. Helmut Holtmann
Control of mRNA degradation by AU-rich elements and interacting proteins
Seminar room 1330, 12.00 h
11.04.2008
Dr. Thomas Binz
Botulinum Neurotoxin Receptors and their Mode of Toxin Interaction
Seminar room 1330, 12.00 h
07.03.2008
Dr. Oliver Dittrich-Breiholz
Analyses of mRNA expression patterns - the central microarray facility of the SFB566)
Seminar room 1330, 12.00 h
01.02.2008
Susan Zimnik
Mutually exclusive Stat1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation (USDDS)
Seminar room 1330, 12.00 h
18.01.2008
Dr. Renate Scheibe
Muscle fiber types:Signaling pathways and physiology of contractions
Seminar room 1330, 12.00 h
07.12.2007
Jessica Schwermann
Cleavage and Polyadenylation Specificity Factor (CPSF) 2 - a new interaction partner of Tristetraprolin (TTP)
Seminar room 1330, 12.00 h
23.11.2007
Dr. Annalisa Mancini
FMIP and Beyond
Seminar room 1330, 12.00 h
09.11.2007
PD Dr. Johannes G. Bode
Cross-talk between JAK/STAT-mediated signal transduction and the p38 MAPK pathway
Seminar room 1330, 12.00 h
02.11.2007
Basant Kumar Tharkur
KSRP is involved in the AU-rich element-dependent degradation of IL-8 mRNA
Seminar room 1330, 12.00 h
19.10.2007
Stefan Sikorra
Clostridial neurotoxins: New insights into sulbstrat specificity
Seminar room 1330, 12.00 h
05.10.2007
Anastassia Vertii
Co-localization of Hsp27 and Akt/PKB in nuclear stress granules
Seminar room 1330, 12.00 h
20.09.2007
Prof. Raymond Kaempfer
Dynamic Refolding of Interferon-Gamma mRNA Enables its Dual Function as Translation Template and Activator of Protein Kinase PKR
Seminar room 1330, 12.00 h
29.6.2007
Dr. Rainer Niedenthal
Heterodimerization - dependent SUMOylation and detection of protein-protein-interaction by SUMOylation
Seminar room 1330, 12.00 h
15.6.2007
Dr. Alexandra Koch
c-abl down-modulates NGFR signaling by interfering with receptor internalization
Seminar room 1330, 13.00 h
20.4.2007
Basant Kumar Thakur
KSRP regulates the turmover of AU-rich element-containing IL8 mRNA
Seminar room 1330, 12.00 h
9.3.2007
Dr. Kirsten Mielke
Differentiation-dependent expression and phosphorylation of p27kip at serine 10 is mediated by the JNK pathway
Seminar room 1330, 13.00 h
16.2.2007
Dr. Renate Scheibe
Role of the p38 MAPK in regulating fast MyHC gene activity during muscle fiber type transformation
Seminar room 1330, 12.00 h
2.2.2007
Dr. Rainer Niedenthal
USDF: a method to analyze function of protein SUMOylation and to identify constitutive and stimulation-dependent SUMOylation
Seminar room 1330, 12.00 h
19.1.2007
Dr. Natalia Ronkina
MK2/3 double deficiency affects p38 MAPK function
Seminar room 1330, 12.00 h
2006
8.12.2006
Dr. Hiroshi Maruta
University Hospital Eppendorf
Signal therapy of cancers: Hunting down the targets along the PAK1 kinase cascades
Seminar room 1330, 12.00 h
07.12.2006
BIOCHEMICAL COLLOQUIUM
Prof. Dr. Johannes Buchner
Inst. f. Chemistry, TU Munich
Molecular chaperones - cellular machines for protein folding
Seminar room Twin Core, 17.00 h
10.11.2006
Dr. Ole-Morten Seternes
The atypical MAP kinases ERK3 and 4 define novel signaling pathways
Seminar room 1330, 12.00 h
27.10.2006
Shashi Kant
Characterization of the protein kinases ERK3 and ERK4 and their interaction with MK5
Seminar room 1330, 12.00 h
13.10.2006
Prof. Theresia Kraft
Point mutations in the myosin head domain associated with Familial Hypertrophic Cardiomyopathy
Seminar room 1330, 12.00 noon
29.9.2006
Meera Shah
Control of Ikappa B-alpha mRNA degradation
Seminar room 1330, 12.00 h
15.9.2006
Dr. Thomas Binz
Analysis of the Botolinum Neurotoxin Types B and G receptor binding site
Seminar room 1330, 12.00 h
9.6.2006
Dr. Natalia Ronkina
Functional analysis of MK3 using gene targeting approach
Seminar room 1330, 12.00 h
19.5.2006
Prof. Helmut Holtmann
Control of inflammatory gene expression by mRNA stabilizing mechanisms
Seminar room 1330, 12.00 h
5.5.2006
Dr. Renate Scheibe
The calcineurin/NFATc1-pathway during fast-to-slow transformation in C2C12 myotubes and primary skeletal muscle cells
Seminar room 1330, 12.00 h
21.4.2006
Shashi Kant
Characterization of ERK3/4 signaling module
Seminar room 1330, 12.00 h
7.4.2006
Dr. Rainer Niedenthal
The Ubc9-fusion directed SUMOylation (UFDS) system: Analysis of the function of protein SUMOylation
Seminar room 1330, 12.00 h
10.3.2006
Dr. Teruko Tamura-Niemann
FMIP: Where are we?
Dr. Rüdiger Pankow
FMP, Berlin
Generation of the conditional FMIP knockout mouse
Seminar room 1330, 12.00 noon
24.02.2006
Stefan Sikorra
Identification of the amino acid residues rendering TI-VAMP insensitive towards Botulinum Neurotoxins B and D
Seminar room 1330, 12.00 h
10.02.2006
Sandra Lopez-Aviles
Dept. Cell Biology, University of Barcelona Med. School
Dual role of the mitotic kinase Srk1 in fission yeast
Seminar room 1330, 12.00 h
09.02.2006
BIOCHEMICAL COLLOQUIUM
Prof. Dr. Alfred Nordheim
Inst. f. Cell Biology, Dept. of Molecular Biology, University of Tübingen
The transcription factor SRF, a sensor of actin dynamics, determines muscle function and neuronal migration
Seminar room MPI, 17.00 h
27.01.2006
Anastassiia Vertii
MK2 is responsible for disruption of Hsp25 oligomers in vivo and for inhibition of cellular stress resistance
Seminar room 1330, 12.00 noon
13.01.2006
Dr. Kirsten Mielke
The cell cycle inhibitory protein p27kip in differentiating neural progenitor cells
Seminar room 1330, 12.00 p.m.
2005
23.12.2005
Dr. C. Reinhardt
Center for Cancer Reserach, Massachusetts Institute of Technology
MAPKAP kinase-2 - characterization of a new player in the checkpoint business
Seminar room 1330 ,12. 00 h
02.12.2005
Dr. Michael Leitges
PKC in vivo functions: lessons from knock out mice
Seminar room 1330 ,12.00 h
18.11.2005
Dr. Rainer Niedenthal
Analysis of protein SUMOylation with the Ubc9-fusion directed SUMOylation system
Seminar room 1330 ,12. 00 h
28.10.2005
Dr. Natalia Ronkina
MK3 knockout: first steps of phenotyping
Seminar room 1330, 12.00 h
30.09.2005
Stefan Mahrhold
Synaptic vesicle (Glyco-)Protein 2C (SV2C)-Receptor Candidate for Botulinum Neurotoxin Type A
Seminar room 1330. 12.00 h
19.08.2005
Gerhard Seisenbacher
Group Prof. Dr. Dr. Ernst Hafen Institute of Zoology ,University of Zürich, Switzerland
Characterization of the MAKAP kinase 2 in Drosophila melanogaster
Seminar room 1330 ,12.00 h
04.02.2005
Dr. Alexandra Koch
The SH2-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via residue 1356 and involves hepatocyte growth factor (HGF) induced lamellipodium formation, cell scattering and cell spreading
Seminar room 1330 ,12.00 h
04.03.2005
Dr. Carsten Frank
Analysis of the Crosstalk between Beta1 Integrin and the EGFR in SOS-F induced Skin Tumors
Seminar room 1330 ,12.00 h
01.04.2005
Andreas Rummel
Interaction with one ganglioside and one protein receptor mediates the neurotoxicity of butolinum neurotoxins
Seminar room 1330 ,12.00 h
15.04.2005
Dr. Edward Hitti
Post-transcriptional regulation of TNF by the Mitogen-Activated Protein-Kinase p38 signaling pathway
Seminar room 1330, 12. 00 h
21.04.2005
Dr. Oleg Timofeev
p38 kinase in cell cycle and tumorogenesis
Seminar room 1330, 16.00 h
03.05.2005
Dr. Wolfgang Obermann
Institute for Genetics, Bonn
The Hsp90 chaperone system, a key regulator of medically relevant signaling molecules
Seminar room 1330 ,13.00 h
03.06.2005
Meera Shah
Structure-function analysis of regulatory mRNA cis-elements
Seminar room 1330 ,12.00 h
10.06.2005
Dr. Kirsten Mielke
The Rac1/JNK pathway in proliferation and migration of glioblatoma and schwannoma cells
Seminar room 1330 ,12.00 h
24.06.2005
Prof. Dr. Dr. Michael Kracht
transcriptional regulation of the chemokine cc12
Seminar room 1330 ,13.00 h
2004
10.12.2004
Dr. Kirsten Mielke
Neurogenisis of expanded embryonic neural stem and progenitor cells
Seminar room 1330 ,12. 00 h
^
Building I 3, level 01, room no. 2020, 12.00 noon