Serological tests of immune parameters

Location Building K3

Plasma, serum and synovial fluid tests are carried out in our Central Laboratory. For urgent inquiries, the laboratory of the Clinical Department of Rheumatology and Immunology can be contacted by telephone on 3632. Consultation appointments can be arranged by calling 0511 532 3014.

 

Diagnostic spectrum

  • Protein determinations: Immunoglobulins, IgG (subclasses), IgM, IgA, IgE, free light chains, CRP highly sensitive, ß2-microglobulin

  • Complement determination: total activity (CH50, AP50), C3, C4, C1 inhibitor, C1 inhibitor activity

  • Cryoglobulins, cryocrit

  • Streptococcal antibodies: antistreptolysin 0 titer, A-DNase B

  • Antistaphylosin titer

  • Rheumatoid factors: CCP, RF quantitative

  • Paraproteins: Immunofixation, Bence-Jones protein in urine

  • Antinuclear antibodies (indirect fluorescence test)

  • Anti-dsDNA antibodies: RIA, Elisa, Crithidia

  • Anti-ENA antibodies: anti-Sm, anti-RNP, anti-SS-B, anti-SS-A, anti-Scl 70, CenP-B, Jo-1,

  • Antibodies against: Rib-P, PM-Scl, Mi-2, RNA polymerase III, fibrillarin, myositis panel (Jo-1, SRP, Ku, PL7, PL12, PM-SCL100)

  • alpha-Fodrin antibody

  • Anti-phospholipid antibodies: cardiolipin IgG / IgM, ß2-glycoprotein IgG / IgM

  • Anticytoplasmic antibodies: cANCA, pANCA, PR3-ANCA, MPO-ANCA

  • Anti-GBM

  • Organ antibodies: antimitochondrial antibodies (AMA), stomach/parietal cells, parotid gland, adrenal gland, striated muscle, smooth muscle, heart muscle

HIV diagnostics

  • Quantitative viral load determination (RT-PCR)
  • Helper cell count determination (FACS)
  • Genetic HIV-1 resistance determination (sequencing of HIV-1 reverse transcriptase and protease, integrase, gp41 and tropism testing, other regions on request)

Consultation appointments can be arranged by calling 0511 532 3637.

 

Synovial fluid analysis:

Examination of the synovial fluid (= synovia analysis) provides a lot of information about the cause of the joint effusion and the underlying disease. The cell count can be used to assess whether it is an "inflammatory effusion" (example: chronic polyarthritis), a "non-inflammatory effusion" (example: osteoarthritis) or a "bloody effusion" (= haemarthrosis, for example after joint trauma).

 

If you have any questions, you can contact the rheumatology laboratory

by telephone: 0511 / 532-3616 or -3632

by fax: 0511 / 532-5648

 

Explanations of laboratory services can be found here.