Publications 2021

  • Böhne C, Chhatwal P, Peter C, Ebadi E, Hansen G, Schlüter D, Bange FC, Bohnhorst B, Baier C. Detection of Serratia marcescens in neonatal intensive care units requires a rapid and comprehensive infection control response starting with the very first case. GMS Hyg Infect Control 2021;16: Doc12.

  • Böning MAL, Parzmair GP, Jeron A, Düsedau HP, Kershaw O, Xu B, Relja B, Schlüter D, Dunay IR, Reinhold A, Schraven B*, Bruder D*. Enhanced susceptibility of ADAP-deficient mice to Listeria monocytogenes infection is associated with an altered phagocyte phenotype and function. Front Immunol 2021;12:724855. *contributed equally

  • Bünsow D, Tantawy E, Ostermeier T, Bähre H, Garbe A, Larsen J, Winstel V. Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection. Virulence 2021;12(1):989-1002.

  • Chhatwal P*, Ebadi E*, Schwab F, Ziesing S, Vonberg RP, Simon N, Gerbel S, Schlüter D, Bange FC, Baier C. Epidemiology and infection control of carbapenem resistant Acinetobacter baumannii and Klebsiella pneumoniae at a German university hospital: a retrospective study of 5 years (2015-2019). BMC Infect Dis 2021; 21(1):1196. *contributed equally

  • Chhatwal P, Woltemate S, Ziesing S, Welte T, Schlüter D, Vital M. Molecular characterization and improved diagnostics of Nocardia strains isolated over the last two decades at a German tertiary care center. Excli j 2021; 20:851-862.

  • Du X, Larsen J, Li M, Walter A, Slavetinsky C, Both A, Sanchez Carballo PM, Stegger M, Lehmann E, Liu Y, Liu J, Slavetinsky J, Duda KA, Krismer B, Heilbronner S, Weidenmaier C, Mayer C, Rohde H, Winstel V, Peschel A. Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle. Nat Microbiol 2021; 6(6):757-768.

  • Faass L*, Stein SC*, Hauke M, Gapp M, Albanese M, Josenhans C. Contribution of heptose metabolites and the cag pathogenicity island to the activation of monocytes/macrophages by Helicobacter pylori. Front Immunol 2021; 12:632154. *contributed equally

  • Felgenhauer F, Schilke R, Ebadi E, Baier C. Hand hygiene in dental students - First results from a project to improve the compliance of students in the clinical study section. Hyg. Med. 2021; 46, 11-12.

  • Fisarova L*, Botka T*, Du X*, Maslanova I, Bardy P, Pantucek R, Benesik M, Roudnicky P, Winstel V, Larsen J, Rosenstein R, Peschel A, Doskar J. Staphylococcus epidermidis phages transduce antimicrobial resistance plasmids and mobilize chromosomal islands. Msphere 2021; 6(3):e00223-21. *contributed equally

  • Galeev A, Suwandi A, Cepic A, Basu M, Baines JF, Grassl GA. The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease. Int J Med Microbiol 2021; 311(3):151487. review.

  • Hillert A, Schultalbers M, Tergast TL, Vonberg RP, Rademacher J, Wedemeyer H, Cornberg M, Ziesing S, Maasoumy B, Höner Zu Siederdissen C. Antimicrobial resistance in patients with decompensated liver cirrhosis and bacterial infections in a tertiary center in Northern Germany. BMC Gastroenterol 2021; 21(1):296.

  • Hoffmann P, Schnepel N, Langeheine M, Künnemann K, Grassl GA, Brehm R, Seeger B, Mazzuoli-Weber G, Breves G. Intestinal organoid-based 2D monolayers mimic physiological and pathophysiological properties of the pig intestine. PLoS One 2021;16(8):e0256143.

  • Kamp JC, Fuge J, Ringshausen FC, Grote-Koska D, Brand K, Graalmann L, Vonberg RP, Welte T, Rademacher J. Pharmacokinetics of meropenem in people with cystic fibrosis - A proof of concept clinical trial. Antibiotics (Basel) 2021; 10(3):292. letter.

  • Katzenberger RH, Rösel A, Vonberg RP. Bacterial survival on inanimate surfaces: a field study. BMC Res Notes 2021; 14(1):97.

  • Kayser MZ,* Seeliger B*, Valtin C, Fuge J, Ziesing S, Welte T, Pletz MW, Chhatwal P, Gottlieb J. Clinical decision making is improved by BioFire Pneumonia Plus in suspected lower respiratory tract infection after lung transplantation: Results of the prospective DBATE-IT(*) study. Transpl Infect Dis 2021; e13725. doi: 10.1111/tid.13725. Online ahead of print. *contributed equally

  • Kleine Bardenhorst S, Berger T, Klawonn F, Vital M, Karch A, Rübsamen N. Data analysis strategies for microbiome studies in human populations - a systematic review of current practice. Msystems 2021; 6(1):e01154-20. overview.

  • Knegendorf L, Schlüter D. Shigellosis. Z Gastroenterol 2021; 59(10:1051-1052. Overview.

  • Kohn M, Lanfermann C, Laudeley R, Glage S, Rheinheimer C, Klos A. Complement and Chlamydia psittaci: Early complement-dependent events are important for DC migration and protection during mouse lung infection. Front Immunol 2021; 12:580594.

  • Kohn M, Lanfermann C, Laudeley R, Glage S, Rheinheimer C, Klos A. Complement and Chlamydia psittaci: Non-myeloid-derived C3 predominantly induces protective adaptive immune responses in mouse lung infection. Front Immunol 2021; 12:626627.

  • Koschel J, Nishanth G, Just S, Harit K, Kröger A, Deckert M, Naumann M, Schlüter D. OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation. Cell Death Differ. 2021; 28:2257-2275.

  • Lanfermann C, Kohn M, Laudeley R, Rheinheimer C, Klos A. Chlamydia trachomatis cross-serovar protection during experimental lung reinfection in mice. Vaccines (Basel) 2021; 9(8):871.

  • Lanfermann C, Wintgens S, Ebensen T, Kohn M, Laudeley R, Schulze K, Rheinheimer C, Hegemann JH, Guzmán CA, Klos A. Prophylactic multi-subunit vaccine against Chlamydia trachomatis: In vivo evaluation in mice. Vaccines (Basel) 2021; 9(6):609 [pii].

  • Lanfermann CM. Development of a prophylactic multi-subunit experimental vaccine against Chlamydia trachomatis in a mouse lung infection model. Dissertation, Hannover Medical School, 2021.

  • Lindenberg M, Almeida L, Dhillon-LaBrooy A, Siegel E, Henriques-Normark B, Sparwasser T. Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infections. J Mol. Med (Berl) 2021; 99(6):817-829.

  • Linke L. Risk factor and cost analysis of CVC-associated sepsis in hematologic oncology patients. Dissertation, Hannover Medical School, 2021

  • Liu B, Ruan J, Chen M, Li Z, Manjengwa G, Schlüter D, Song W, Wang X. Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases. Mol Psychiatry 2021; doi: 10.1038/s41380-021-01233-8. Online ahead of print. *authors contributed equally. Overview.

  • Missiakas D, Winstel V. Selective host cell death by Staphylococcus aureus: A strategy for bacterial persistence. Front Immunol 2021; 11:621733. overview.

  • Osbelt L, Wende M, Almási E, Derksen E, Muthukumarasamy U, Lesker TR, Galvez EJC, Pils MC, Schalk E, Chhatwal P, Färber J, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T. Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition. Cell Host Microbe 2021; 29(11):1663-1679.

  • Pannewick B, Baier C, Schwab F, Vonberg RP. Infection control measures in nosocomial MRSA outbreaks-Results of a systematic analysis. PLoS One 2021; 16(4):e0249837.

  • Pink I, Raupach D, Fuge J, Vonberg RP, Hoeper MM, Welte T, Rademacher J. C-reactive protein and procalcitonin for antimicrobial stewardship in COVID-19. Infection 2021; 49(5):935-943.

  • Rath S*, Rox K*, Kleine Bardenhorst S*, Schminke U, Dörr M, Mayerle J, Frost F, Lerch MM, Karch A, Brönstrup M, Pieper DH, Vital M. Higher trimethylamine-N-oxide plasma levels with increasing age are mediated by diet and trimethylamine-forming bacteria. Msystems 2021; 6(5):e0094521. *contributed equally

  • Riat A*, Suwandi A*, Ghashang SK, Buettner M, Eljurnazi L, Grassl GA, Gutenbrunner C, Nugraha B. Ramadan fasting in Germany (17-18 h/day): Effect on cortisol and brain-derived neurotrophic factor in association with mood and body composition parameters. Front Nutr 2021; 8:697920. *contributed equally

  • Rox K, Rath S, Pieper DH, Vital M, Bronstrup M. A simplified LC-MS/MS method for the quantification of the cardiovascular disease biomarker trimethylamine-N-oxide and its precursors. J Pharm Anal 2021; 11(4):523-528.

  • Ruan J, Miao X, Schlüter D, Lin L, Wang X. Extracellular vesicles in neuroinflammation: pathogenesis, diagnosis, and therapy. Mol Ther 2021; 29(6):1946-1957. review.

  • Schlüter D, Schulze-Niemand E, Stein M, Naumann M. Ovarian tumor domain proteases in pathogen infection. Trends Microbiol 2021; 30(1):22-33.overview.

  • Singhal R, Donde H, Ghare S, Stocke K, Zhang J, Vadhanam M, Reddy S, Gobejishvili L, Chilton P, Joshi-Barve S, Feng W, McClain C, Hoffman K, Petrosino J, Vital M, Barve S. Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice. Gut Microbes 2021; 13(1):1946367.

  • Stolzer I, Schickedanz L, Chiriac MT, Lopez-Posadas R, Grassl GA, Mattner J, Wirtz S, Winner B, Neurath MF, Günther C. STAT1 coordinates intestinal epithelial cell death during gastrointestinal infection upstream of Caspase-8. Mucosal Immunol 2021; 15(1):130-142.

  • Timm ME, Rossberg W, Vonberg RP, Lenarz T, Helmstaedter V. "Hit hard and fast" - 2 cases of sepsis with focus in the head and neck region. Laryngorhinootology 2021; 100(5):397-399.

  • Tomsic I, Ebadi E, Gossé F, Hartlep I, Schipper P, Krauth C, Schock B, Chaberny IF, von Lengerke T. Determinants of orthopedic physicians' self-reported compliance with surgical site infection prevention: results of the WACH-trial's pilot survey on COM-B factors in a German university hospital. Antimicrob. Resist Infect Control 2021; 10(1):67.

  • Vonberg RP. Current epidemiology and diagnostics in microbiology (36): Panton--valentine leukocidin (PVL) in Staphylococcus aureus. Journal of Infection Therapy 2021; 42(1):3. overview.

  • Vonberg RP. Current Epidemiology and Diagnostics in Microbiology (37): Analysis of Nosocomial Outbreaks for the Prevention of Nosocomial Infections. Journal of Infection Therapy 2021; 42(2):15. overview.

  • Vonberg RP. Current epidemiology and diagnostics in microbiology (38); Case report: schistosomiasis - urogenital schistosomiasis without prior tropicalization. Journal for Infection Therapy 2021; 42(3):27. overview.

  • Vonberg RP. Current epidemiology and diagnostics in microbiology (39): Antibiotic stewardship (ABS). Journal of Infection Therapy 2021; 42(4):38. overview.

  • Vonberg RP. Current Epidemiology and Diagnostics in Microbiology (40): Laboratory errors in microbiology and their consequences for the Clinical Department. Journal of Infection Therapy 2021; 42(5):51. overview.

  • Vonberg RP. Current epidemiology and diagnostics in microbiology (41): Toxoplasmosis: When the parasites take over. Journal of Infection Therapy 2021; 42(6):63. overview.

  • Vonberg RP. Antibiotics in pregnancy. Gyn 2021; 26(3):212-221. overview.

  • Wieland K. Nosocomial outbreaks caused by Acinetobacter baumannii and Pseudomonas aeruginosa - results of a systematic review. Cumulative dissertation, Hannover Medical School, 2021

  • Winstel V, Schneewind O, Missiakas D. Staphylococcus aureus and related staphylococci. In: Practical handbook of microbiology, Lorrence H. Green, and Emanuel Goldman, eds. (Boca Raton London New York: CRC Press), 2021. pp. 543-566. 2021.

  • Wulff A*, Baier C*, Ballout S, Tute E, Sommer KK, Kaase M, Sargeant A, Drenkhahn C, Infection Control Study Group, Schlüter D, Marschollek M*, Scheithauer S*. Transformation of microbiology data into a standardized data representation using OpenEHR. Sci Rep 2021; 11(1):10556. *contributed equally

  • Wulff A, Baier C, Marschollek M, Scheithauer S. 2021. SmICS: A smart solution for automated outbreak detection in hospitals. Gesundhyte.de. 14:46-49.