Clinical pharmacology of inflammation

Prof. Dr. med. Dirk O. Stichtenoth

The aim of the research is to develop more effective and safer anti-inflammatory drugs.

The clinical-pharmacological research approach is characterized by

• basic biochemical research and analytics
• Exploration of new therapeutic approaches
• Investigation of approved drugs with regard to their effect on metabolic pathways and processes.

Topics

• In vivo studies on the effects of specific inhibitors of inducible cyclooxygenase (COX-2) on prostaglandin metabolism and body functions in humans and animals.
• NO metabolism and oxidative stress in acute and chronic inflammation and their pharmacological influence.
• Endocannabinoids and inflammation