Publications 2018

  • de Gonzalo-Calvo D, Thum T. Circulating non-coding RNAs as biomarkers to predict and monitor the response to exercise: Chances and hurdles. Eur Heart J. 2018;39:3552. https://www.ncbi.nlm.nih.gov/pubmed/30060047
  • Christoffersson J, Meier F, Kempf H, Schwanke K, Coffee M, Beilmann M, Zweigerdt R, Mandenius CF. A cardiac cell outgrowth assay for evaluating drug compounds using a cardiac spheroid-on-a-chip device. Bioengineering (Basel). 2018;5:10.3390/bioengineering5020036. https://www.ncbi.nlm.nih.gov/pubmed/29734702
  • Hobuss L, Bar C, Thum T. Long non-coding RNAs: At the heart of cardiac dysfunction? Front Physiol. 2019;10:30. https://www.ncbi.nlm.nih.gov/pubmed/30761015
  • Jung M, Dodsworth M, Thum T. Inflammatory cells and their non-coding RNAs as targets for treating myocardial infarction. Basic Res Cardiol. 2018;114:4-018-0712-z. https://www.ncbi.nlm.nih.gov/pubmed/30523422
  • Thum T. Translational opportunities and challenges of long noncoding RNAs in cardiac regeneration. J Am Coll Cardiol. 2018;72:551-552. https://www.ncbi.nlm.nih.gov/pubmed/29945752
  • Polten F, Reboll M, Widera C, Kempf T, Bethmann K, Gupta P, Miglietta J, Pekcec A, Tillmanns J, Bauersachs J, Giannitsis E, Pich A, Wollert KC. Plasma concentrations of myeloid-derived growth factor in healthy individuals and patients with acute myocardial infarction as assessed by multiple reaction monitoring-mass spectrometry. Anal Chem. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30543396
  • Madrahimov N, Khalikov A, Boyle EC, Natanov R, Knoefel A-K, Siemeni T, Hoeffler K, Haverich A, Maus U, Kuehn C. Veno-venous extracorporeal membrane oxygenation in a mouse. JoVE. 2018:e58146. https://www.jove.com/video/58146
  • Bengel FM, Ross TL. Emerging imaging targets for infiltrative cardiomyopathy: Inflammation and fibrosis. J Nucl Cardiol. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29968156
  • Chatterjee S, de Gonzalo-Calvo D, Derda AA, Schimmel K, Sonnenschein K, Bavendiek U, Bauersachs J, Bar C, Thum T. Leukocyte telomere length correlates with hypertrophic cardiomyopathy severity. Sci Rep. 2018; 8:11227-018-29072-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060137/
  • de Gonzalo-Calvo D, Cediel G, Bar C, Nunez J, Revuelta-Lopez E, Gavara J, Rios-Navarro C, Llorente-Cortes V, Bodi V, Thum T, Bayes-Genis A. Circulating miR-1254 predicts ventricular remodeling in patients with ST-segment-elevation myocardial infarction: A cardiovascular magnetic resonance study. Sci Rep. 2018; 8:15115-018-33491-y. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181905/
  • Derda AA, Pfanne A, Bar C, Schimmel K, Kennel PJ, Xiao K, Schulze PC, Bauersachs J, Thum T. Blood-based microRNA profiling in patients with cardiac amyloidosis. PLoS One. 2018; 13:e0204235. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192556/
  • Koch L, Deiwick A, Franke A, Schwanke K, Haverich A, Zweigerdt R, Chichkov B. Laser bioprinting of human induced pluripotent stem cells-the effect of printing and biomaterials on cell survival, pluripotency, and differentiation. Biofabrication. 2018; 10:035005-5090/aab981. https://www.ncbi.nlm.nih.gov/pubmed/29578448
  • Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic PM, Skouri H, Zimmermann WH, Mebazaa A. Treatments targeting inotropy. Eur Heart J. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30295807
  • Madrahimov N, Boyle EC, Gueler F, Goecke T, Knofel AK, Irkha V, Maegel L, Hoffler K, Natanov R, Ismail I, Maus U, Kuhn C, Warnecke G, Shrestha ML, Cebotari S, Haverich A. Novel mouse model of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2018; 53:186-193. https://www.ncbi.nlm.nih.gov/pubmed/28977367
  • Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner J-, Pfister R, Ghanem A, Busch H-, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H. Empfehlungen zur extrakorporalen kardiopulmonalen reanimation (eCPR). Medizinische Klinik - Intensivmedizin und Notfallmedizin. 2018; 113:478-486. https://doi.org/10.1007/s00063-018-0452-8
  • Michels G, Wengenmayer T, Hagl C, Dohmen C, Bottiger BW, Bauersachs J, Markewitz A, Bauer A, Grasner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H. Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC. Clin Res Cardiol. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30361819
  • Natanov R, Gueler F, Falk CS, Kuhn C, Maus U, Boyle EC, Siemeni T, Knoefel AK, Cebotari S, Haverich A, Madrahimov N. Blood cytokine expression correlates with early multi-organ damage in a mouse model of moderate hypothermia with circulatory arrest using cardiopulmonary bypass. PLoS One. 2018; 13:e0205437. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181365/
  • Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Gohring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U. Differentiation of human pluripotent stem cells into functional endothelial cells in scalable suspension culture. Stem Cell Reports. 2018; 10:1657-1672. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995343/
  • Wolling H, Konze SA, Hofer A, Erdmann J, Pich A, Zweigerdt R, Buettner FFR. Quantitative secretomics reveals extrinsic signals involved in human pluripotent stem cell cardiomyogenesis. Proteomics. 2018; 18:e1800102. https://www.ncbi.nlm.nih.gov/pubmed/?term=29905012
  • Wert L, Hanke JS, Dogan G, Ricklefs M, Fleissner F, Chatterjee A, Feldmann C, Haverich A, Schmitto JD. Reduction of driveline infections through doubled driveline tunneling of left ventricular assist devices-5-year follow-up. J Thorac Dis. 2018; 10:S1703-S1710. www.ncbi.nlm.nih.gov/pubmed/30034842
  • Dogan G, Hanke JS, Ricklefs M, Chatterjee A, Feldmann C, Mashaqi B, Deniz E, Haverich A, Schmitto JD. MitraClip procedure prior to left ventricular assist device implantation. J Thorac Dis. 2018; 10:S1763-S1768. www.ncbi.nlm.nih.gov/pubmed/30034850
  • Ricklefs M, Hanke JS, Dogan G, Chatterjee A, Feldmann C, Deniz E, Korte W, Kirchhoff F, Haverich A, Schmitto JD. Successful HeartMate 3 implantation in isolated right heart failure-first in man experience of right heart configuration. J Thorac Dis. 2018; 10:S1834-S1837. www.ncbi.nlm.nih.gov/pubmed/ 30034861
  • Grund A, Szaroszyk M, Doppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Muller OJ, Bauersachs J, Heineke J. A gene therapeutic approach to inhibit CIB1 ameliorates maladaptive remodeling in pressure overload. Cardiovasc Res. 2018. www.ncbi.nlm.nih.gov/pubmed/29931050
  • Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J. Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice. J Mol Cell Cardiol. 2018. www.ncbi.nlm.nih.gov/pubmed/30118791
  • Bauersachs J, Heymans S. Scientific updates on the interaction of genes, epigenetics and multi-cellularity in cardiovascular diseases, the working group of myocardial function of the ESC. Cardiovasc Res. 2018. www.ncbi.nlm.nih.gov/pubmed/29992298
  • Sieweke JT, Pfeffer TJ, Berliner D, Konig T, Hallbaum M, Napp LC, Tongers J, Kuhn C, Schmitto JD, Hilfiker-Kleiner D, Schafer A, Bauersachs J. Cardiogenic shock complicating peripartum cardiomyopathy: Importance of early left ventricular unloading and bromocriptine therapy. Eur Heart J Acute Cardiovasc Care. 2018: 2048872618777876. www.ncbi.nlm.nih.gov/pubmed/29792513
  • Crespo-Leiro MG, Metra M, Lund LH, Milicic D, Costanzo MR, Filippatos G, Gustafsson F, Tsui S, Barge-Caballero E, De Jonge N, Frigerio M, Hamdan R, Hasin T, Hulsmann M, Nalbantgil S, Potena L, Bauersachs J, Gkouziouta A, Ruhparwar A, Ristic AD, Straburzynska-Migaj E, McDonagh T, Seferovic P, Ruschitzka F. Advanced heart failure: A position statement of the heart failure association of the european society of cardiology. Eur J Heart Fail. 2018. www.ncbi.nlm.nih.gov/pubmed/ 29806100
  • Koestenberger M, Avian A, Cantinotti M, Hansmann G, for the European Pediatric Pulmonary Vascular Disease Network. Tricuspid annular plane systolic excursion (TAPSE) in pediatric pulmonary hypertension: integrating right ventricular ejection efficiency (RVEe) into advanced multi-parametric imaging. International Journal of Cardiology. 2018 (in press).
  • Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis SA, Rog-Zielinska EA, Kourembanas S, Jonigk D, Hansmann G. PPARgamma agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation. Sci Transl Med. 2018; 10:10.1126/scitranslmed.aao0303. www.ncbi.nlm.nih.gov/pubmed/29695452
  • Koestenberger M, Avian A, Gamillscheg A, Sallmon H, Grangl G, Burmas A, Schweintzger S, Kurath-Koller S, Cvirn G, Hansmann G. Right ventricular base/apex ratio in the assessment of pediatric pulmonary arterial hypertension - results from the european pediatric pulmonary vascular disease network. Clin Cardiol. 2018. www.ncbi.nlm.nih.gov/pubmed/ 29896859
  • Thackeray JT, Hupe HC, Wang Y, Bankstahl JP, Berding G, Ross TL, Bauersachs J, Wollert KC, Bengel FM. Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction. J Am Coll Cardiol. 2018; 71:263-275. www.ncbi.nlm.nih.gov/pubmed/29348018
  • Sieweke JT, Berliner D, Tongers J, Napp LC, Flierl U, Zauner F, Bauersachs J, Schafer A. Mortality in patients with cardiogenic shock treated with the Impella CP microaxial pump for isolated left ventricular failure. Eur Heart J Acute Cardiovasc Care. 2018; 2048872618757393. www.ncbi.nlm.nih.gov/pubmed/29405734
  • Koestenberger M, Avian A, Sallmon H, Gamillscheg A, Grangl G, Kurath-Koller S, Schweintzger S, Burmas A, Hansmann G. The right ventricular outflow tract in pediatric pulmonary hypertension-data from the european pediatric pulmonary vascular disease network. Echocardiography. 2018; 35:841-848. www.ncbi.nlm.nih.gov/pubmed/29505663
  • Hanke JS, Dogan G, Zoch A, Ricklefs M, Wert L, Feldmann C, Bara C, Shrestha M, Tillmanns J, Kempf T, Bauersachs J, Haverich A, Schmitto JD. One-year outcomes with the HeartMate 3 left ventricular assist device. J Thorac Cardiovasc Surg. 2018; 156:662-669.  www.ncbi.nlm.nih.gov/pubmed/29525258