Human stem cell models, Parkinson's syndromes, dystonia

Our basic science research analyzes human induced pluripotent stem cell models derived from patients with neurodegenerative diseases and movement disorders (Parkinson's syndromes, dystonia, ALS) to contribute to the development of new therapeutic strategies.

The following images show immunocytochemical staining (left, GABA in red, TUJ1 in green, DAPI in blue) and calcium imaging (right, Fura-2) of the differentiated neurons of a dystonia patient (hereditary SGCE dystonia).

Clinical research in the field of Parkinson's syndromes and dystonia examines, among other things, the effect of potential therapeutic agents and the care situation of patients and their carers in various studies.

 

Contact:

 

Prof. Dr. med. Florian Wegner

Senior Physician

Clinical Department of Neurology

Hannover Medical School

Carl-Neuberg-Str. 1

30625 Hanover

Phone: 0511 - 532 33455

Fax: 0511 - 532 3115

E-Mail: Wegner.Florian@mh-hannover.de

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