Association of human FOS promoter variants with the occurrence of knee-osteoarthritis in a case control association study. Int J Mol Sci. 20: 1382. Welz B, Bikker R, Junemann J, Christmann M, Neumann K [...] Westphal A, Suwandi A, Grassl GA, Brand K, Chan AC, Föger N, Lee KH. (2018 ). Surface receptor Toso controls B cell-mediated regulation of T cell immunity. J Clin Invest. 128: 1820-1836. Jyotsana N, Sharma [...] Dittrich-Breiholz O, Huber R, Brand K. (2017 ). TNF phase III signaling in tolerant cells is tightly controlled by A20 and CYLD. Cell Signal. 37: 123-135. Frantzi M, Van Kessel KE, Zwarthoff EC, Marquez M, Rava
response and pathological autoimmunity. The focus is on regulatory T cells (Tregs) as the central control center of immune tolerance in the liver and intestine. We analyze how function, stability and antigen [...] and cell engineering Our goal is antigen-specific and precise immunomodulation that specifically controls pathogenic immune reactions without unnecessarily weakening protective immunity. To this end, we [...] for therapeutic purposes. These approaches are relevant for applications in autoimmunity, in the control of therapy-associated autoimmunity (irAEs) and in transplantation medicine. The work has a translational
Todd Kuiken (rehabilitation physician) and Gregory Dumanian (plastic surgeon) to improve prosthesis control. In a complex microsurgical procedure, a selected severed nerve in the amputation stump is redirected [...] socket and reinnervates them. This creates a new and additional "myosignal" that can be used to control the prosthesis. This also reduces the likelihood of painful neuromas developing (again), as the growth [...] Sensory feedback on the residual limb in particular is considered crucial for improving prosthetic control, reducing phantom pain and improving embodiment (body awareness). TSR surgery can be performed to
anaesthetic. Several small tissue samples are then taken from the abnormal findings under sonographic control. This procedure only takes a few minutes and is well tolerated. The puncture site is treated with
activities. The tasks include: Continuous development of the clinic's research structures Continuous controlling of the research budget Content design of the research website Support in third-party funding a
Request cards and study stickers must be used for orders to the laboratory. These are available at the control center of the Institute of Clinical Chemistry and Central Laboratory (Tel. 2515). In the case of
medically-occupationally oriented rehabilitation aftercare: long-term results of the randomized controlled multicenter study. Rehabilitation 2016; 55 (2): 108-114 Gottschling-Lang A, Franze M, Hoffmann [...] and health-related quality of life of healthy young men in summer time in Germany: A prospective controlled study. Appetite 2016; doi: 10.1016/j.appet.2016.12.030 Radhakrishnan S, Kohler F, Gutenbrunner [...] Effects of acupuncture on quality of life and pain in patients with osteoporosis-a pilot randomized controlled trial. Arch Osteoporos 2016; 11(1): 34 Schwarze M, Egen C, Gutenbrunner C, Schriek S. Early Workplace
addiction refers to the derailed use of online games over which those affected increasingly lose control. School, work and social contacts are neglected in favour of excessive online gaming," reports Prof [...] am without making an appointment. In the group therapies, among other things, strategies for self-control and reduction of behavioural excesses are built up, but it is also about dealing with relapses or
processing of audiovisually presented speech in patients with schizophrenia compared to healthy control subjects. The accompanying animation shows the surface reconstruction of the human cerebral cortex [...] processing of audiovisually presented speech in patients with schizophrenia compared to healthy control subjects. The measurement of brain activity during speech perception in this experiment takes about
able to develop any cell type. With the help of biological or chemical signals, the hPSC can be controlled, for example, so that they only produce pure heart muscle cells. These can then grow together to [...] hPSC grow into three-dimensional cell aggregates in a hydrogel made of proteins and observed the controlled development in so-called heart organoids," says Dr. Lika Drakhlis, first author of the study. In