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Scalable process for differentiating pluripotent stem cells into definitive endoderm

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definitive endoderm from human pluripotent stem cells under defined and scalable culture conditions. Nat Protoc 16, 1581–1599 (2021). doi.org/10.1038/s41596-020-00470-5

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January 2025 Promotions

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Graduations January 2025 Copyrights: Dr. rer. nat. Zulaikha Malik Congratulations on acheiving a milestone ! Svenja Hanna Bothe from the Department of Neurology ' Investigation of compounds identified

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PD Dr. rer. nat. Mamta Amrute

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Mamta Amrute-Nayak PD Dr. rer. nat. Contact ► Mamta Amrute Tel: +49 511 532 -2754 (Office), -3654 (Lab) Fax: +49 511 532-161215 Address: 30625 Hannover, Carl-Neuberg-Str.1, Germany Building J03, Level [...] Thome S, Ma X, Amrute-Nayak M , Finigan A, Kitt L, Masters L, James JR, Shi Y, Meng G, Mallat Z. Nat Commun. 2017 Jun 28;8:15986. doi: 10.1038/ncomms15986., PMID: 28656979; PubMed ATP turnover by individual [...] regulate dynein-dynactin copy number on individual transcript cargoes. Amrute-Nayak M , Bullock SL. Nat Cell Biol. 2012 Feb 26; 14(4):416-23. doi: 10.1038/ncb2446., PMID: 22366687; PubMed Targeted optimization

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Work Group Lochner

Relevance: 69%
 

rboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5(+) intestinal stem cell function. Nat Commun. 13(1):3998. Mamareli, P, F Kruse, C Lu, M Guderian, S Floess, K Rox, DSJ Allan, JR Carlyle [...] 2014. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. Nat Med 20(11):1327-1333. (*contributed equally) Sawa, S, M Lochner, N Satoh-Takayama, S Dulauroy, M Berard [...] cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat Immunol. 12(4):320-326. Lochner, M, C Ohnmacht, L Presley, P Bruhns, M Si-Tahar, S Sawa, G Eberl. 2011

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Teaching

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Pharmacology and Toxicology M.Sc. Biochemistry Organisation: PD Dr. rer. nat. Astrid Rohrbeck, Institute of Toxicology Dr. rer. nat. Sabine Wolter, Institute of Pharmacology Module manual Module materials

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AG Kraft

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function of the sarcomere. Group members Prof. Dr. rer. nat. Theresia Kraft Dipl. Ing. (FH) Edgar Becker Dipl. Ing. (FH) Faramarz Matinmehr Dr. rer.nat. Ante Radocaj Qualification work cand med. Vanessa Dieling

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RG Zweigerdt

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Instruments (Hamburg, Germany) Selected own (co-) publications on Bioprocess development Ackermann et al. Nat Protoc 2022 ( https://www.nature.com/articles/s41596-021-00654-7 ), Manstein et al. STAR Protoc. 2021 [...] via%3Dihub ), Sahabian et al. Cells 2019 ( https://www.mdpi.com/2073-4409/8/12/1571 ), Ackermann et al. Nat Commun. 2018 ( https://www.nature.com/articles/s41467-018-07570-7 ), Olmer et al. Stem Cell Reports [...] https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.5966/sctm.2015-0253 ), Kempf et al. Nat Protoc. 2015 ( https://www.nature.com/articles/nprot.2015.089 ), Kempf et al. Stem Cell Reports. 2014

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Congratulations to our PhD students for their successful defenses!

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Graduations June 2025 Copyrights: Dr. rer. nat. Zulaikha Malik Congratulations on this important stage in the lives of our 8 PhD students! They successfully defended their theses on 06.06.2025 as part

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Immunology, infection and imaging

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vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures. Nat Commun. 2022 Apr 19;13(1):2022. Rastogi A, Robert PA*, Halle S*, Meyer-Hermann M*. Evaluation of CD8 [...] P, Hornef MW, Fulde M. The olfactory epithelium as a port of entry in neonatal neurolisteriosis. Nat Commun. 2018 Oct 15;9(1):4269. Stahl FR, Jung R, Jazbutyte V, Ostermann E, Tödter S, Brixel R, Kemmer

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Robert Lindner, Dr. rer. nat.

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Dr. rer. nat. Robert Lindner Copyright: Dr. rer. nat. Robert Lindner, Neuroanatomy and Cell Biology, MHH Education and Professional Experience 1982–1988 Studied biology at the Technical University and

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