approval by the PEI ) Investigational drugs GMP-compliant production of cell or tissue preparations as test products for e.g. clinical trials (after the required validation and extension of the manufacturing
on) cell-matrix adhesion Adeno-associated virus production Mouse models of dementia, behavioral testing for cognition and locomotion TEAM: Saskia Bosdorf, PhD student Alina Brüge, PhD student Julia Kleinert
Prof. Dr. Tillmann Krüger (Research Group: Sexual Medicine and Affective Neuroscience), is examining test subjects with the aim of gaining a better understanding of the neurobiological basis of paedophilia
body fluids Anesthesia and preparation of vertebrates for experiments Carrying out toxicological tests In addition, students acquire the skills and knowledge taught in six selected elective qualifications
impact,” says the molecular physician. In order to find the best CAR candidate, the researchers are testing various immune switches that, in addition to hyperactivation, are also supposed to prolong the survival [...] Schambach. If suitable candidates for the immune switches are found, the hyperactivated NK cells are tested for their efficacy and safety. This is done in cell culture, in surgically removed tumour tissue
needed for this severe liver disease," emphasises the liver expert. In the current study, the drug was tested on a larger number of patients to see whether efficacy and safety could be confirmed in many different [...] existence, because for its continued existence in the body it must always infect new liver cells. "We tested the antiviral activity on 150 patients who were infected with both HBV and HDV," says Professor Cornberg
differences between the VDP values were quantified using Bland-Altman analysis and tested using the Wilcoxon signed rank test. In a regional comparison of the VD maps, the spatial overlap and Sørensen-Dice
If the results are promising, we plan an immediate translation "from bench to bedside" and the testing of A1AT in a clinical phase 1 study in high-risk patients for the prevention of severe COVID-19 courses [...] project is to facilitate urgent and efficient increases in the capacity for collection, storage and testing of CCP for the treatment of COVID-19 patients to improve their health condition, reduce mortality
establish the diagnosis of CF or a CFTR-associated disorder when CF is clinically suspected, or to test the efficacy of drugs in clinical trials to see if they attenuate or even compensate for the underlying [...] severe mutation in Europe, so that we can use p.Phe508del homozygous CF patients as an example to test which environmental factors and which genetic factors outside the causally affected gene modulate
the Central Laboratory, there has been no going back to the old system and the old premises. All the test material for the departments involved ends up in a central location in the new building, where it [...] all, of course, while examination operations in the old areas were maintained in their tried and tested form. Hats off to the medical staff and the TAs, who put their hearts and souls into their work and