specifically to the genetic characteristics of the tumor and its growth inhibited. This is made possible by molecular genetic tests that determine the exact changes in the genetic material responsible [...] Platform (CCP), support networking and the secure exchange of data between different research institutions. Data Protection is of the utmost importance in order to protect sensitive patient data. Comprehensive [...] evaluation of quality assurance data. The KKN is involved in the research activities as a partner institution of the CCC Lower Saxony. The Epidemiological State Cancer Registry of Lower Saxony (EKN) records

leader Prof. Dr. Daniel P. Depledge Medizinische Hochschule Hannover (Hannover Medical School) Institute of Virology, OE5230 Carl-Neuberg-Str. 1 30625 Hannover Phone +49 (0) 511 532 4310 Departmental Secretary [...] modifications in viral infections. In 2019 he became an Assistant Professor at NYU before joining the Institute of Virology at the Hannover Medical School (MHH) in 2021 as a DZIF Associate Professor. Alumni of [...] - Selected articles, reviews, and book chapters: Depledge DP , Breuer J. Varicella-Zoster Virus-Genetics, Molecular Evolution and Recombination. Curr Top Microbiol Immunol. 2021. https://doi.org/10.10

Theories of the State JC Political Institutions and Public Administration JF Political Institutions and Public Administration (North America) JJ Political Institutions and Public Administration (United [...] g QT 34-37 Human Physiology QT 104-172 Physiology, Hygiene QT 180-245 Leisure Activities, Sports Medicine QT 250-275 Zeitschriften / Periodicals QU - Biochemistry, Cell Biology and Genetics Reference Works [...] Carbohydrates, Lipids QU 75-99 Biochemistry of the Human Body QU 100-133 Enzymes QU 135-144 Nutrition, Vitamins QU 145-220 Cells QU 300-375 Genetics QU 450-560 Zeitschriften / Periodicals QV - Pharmacology

and book contributions (since 2007) Institute for Ethics, History and Philosophy of Medicine Please find below the research articles published by members of our Institute. Our recent publications can be found [...] Mueller R, Aghdassi AA, Lerch MM, Salloch S (2022): Genetic Testing for Rare Diseases: A Systematic Review of Ethical Aspects. Frontiers in genetics vol. 12 701988. doi :10.3389/fgene.2021.701988 Kühlmeyer [...] study. Eur J Hum Genet 2018;26(11):1572-1581 Langhof H, Schwietering J, Strech D. Practice evaluation of biobank ethics and governance: current needs and future perspectives J Med Genet 2019;56(3):176-185

organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis (from left) How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers [...] producing a heart-forming organoid (HFO) and reproducing the entire path to the early stage of a human heart in cell culture. One unsolved problem in science to date has been the development of a model [...] that simulates heart development and haematopoiesis in combination. Haematopoiesis begins in the human embryo after the fourth week in the aorta, close in time and location to the cardiac anlage. Building

computer-assisted and statistical approaches to investigate the effect of genetic factors - at a variety of molecular levels (e.g. genetics, metabolomics), immunological parameters and functions as well as infectious [...] sciences. The "Who's Who" of science also provides information about the countries and research institutions in which the scientific elite work. 336 of these experts work in Germany, putting it in fourth [...] pulmonary hypertension, i.e. pulmonary hypertension. Professor Dr Thomas Thum is Director of the MHH Institute for Molecular and Translational Therapy Strategies. For many years, the cardiologist and bioscientist

in pediatric patients is also being researched clinically as part of a cooperation with the Human Genetics Department at Hannover Medical School (Dr. Spangenberg). This working group is also involved

Biology (BM P 1) Cell Biology (BM P 2) Physiology/Pathophysiology (BM P 3) Immunology (BM P 4) Human Genetics (BM P 5) Virology (BM P 6) Responsibility in Biomedicine (BM P 7) Omics techniques, biostatistics

hepatic diseases and make them the target of innovative treatment strategies. To this end, we use human induced pluripotent stem cells (iPS cells) in many projects in order to have patient-specific stem [...] CRISPR/Cas9 technology for precise genome editing in order to be able to correct disease-specific genetic mutations in a targeted manner. With regard to the public debate on the use of pluripotent (embryonic) [...] genome editing procedures, we are involved in interdisciplinary discourse with partners in the humanities. Research projects Induced Pluripotent Stem Cell-Derived Hepatobiliary Organoids for Studies of

relevant. We have to learn to separate neutral from pathogenic variants from the large number of genetic changes. Bioinformatics will therefore play a decisive role not only in the evaluation of the enormous [...] gene variants." Doris Steinemann Staff members Doris Steinemann , Prof. Dr. rer. nat., specialist human geneticist, Director Winfried Hofmann , Dr. rer. nat., research associate, bioinformatics, deputy [...] development of a disease. To detect intronic and structural variants, we use state-of-the-art molecular genetic techniques such as genome sequencing and optical genome mapping (OGM; https://bionanogenomics.com)