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Welcome to the MHH
Searched for "Institute+for+human+genetic". Found 215 results in 5 Millisekunden.

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Member departments

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stem cell therapy Skin tumor center Cardiac, thoracic, transplant and vascular surgery Human genetics I Institute of Immunology K Cardiology and Angiology Pediatric Surgery Pediatric Oncology Center Clinical [...] Intensive Care Medicine Pharmacy Eye Clinic B Biobank - Hannover Unified Biobank (HUB) Biometry - Institute of Biometry Breast Center C Cellular Therapy Center D Dermatology, Allergology and Venereology E

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Professors Program

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the Institute of Experimental Haematology. Doris Steinemann Doris Steinemann is a W2 professor for "Functional Genomics". She heads the Functional Genomics TEAM at the Institute of Human Genetics. Her [...] focuses on identifying the significance of genetic changes in hereditary tumor diseases. The aim of her research is to use the latest techniques to identify genetic changes that may represent a predisposition

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REBIRTH funding continued

Relevance: 69%
 

of Veterinary Medicine Hannover (TiHo), the Fraunhofer Institute for Toxicology and Experimental Medicine, the Institute of Farm Animal Genetics in Mariensee, the Helmholtz Centre for Infection Research [...] (MHH): On June 15th the German Research Foundation (DFG) and the German Council of Science and Humanities (Wissenschaftsrat, WR) announced further funding of the Cluster of Excellence REBIRTH (from Re [...] federal and state governments. Clusters of Excellence are, together with graduate schools and institutional strategies, the three funding lines of the Excellence Initiative. At the press conference the

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Publications and Outreach

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Protocols in Human Genetics. Curr Protoc Hum Genet. 10.1002/cphg.46. Guadix, J.A., Orlova, V.V., Giacomelli, E., Bellin, M., Ribeiro, M.C., Mummery, C.L., Pérez-Pomares, J.M., Robert Passier (2017). Human pluripotent [...] aberrations in human embryonic stem cells, Ivana Barbaric, July 2017, 33rd Annual Meeting European Society of Human Reproduction and Embryology, Geneva, Switzerland Genetic changes in human pluripotent stem [...] USA Detection of genetic mosaicism in human pluripotent stem cell cultures, Ivana Barbaric, USF, October 2016; ISCI Workshop: Origins and Implications of Pluripotent Stem Cell Genetic and Epigenetic I

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Prof. Dr. med. Martin Sauer

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head of the interdisciplinary stem cell transplant program at the MHH according to JACIE. He studied Human medicine at the Universities of Regensburg, Erlangen and Rennes. He trained as a specialist in pediatrics [...] transplantation took place at the University of Minnesota, one of the world's largest Facilities or Institutions for pediatric bone marrow transplantation. His clinical teachers and mentors included Norma Ramsay [...] transplantation of children with acute myeloid leukemia (AML) and cell therapy approaches with genetically modified immune cells and hematopoietic stem cells.

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RG Martin

Relevance: 68%
 

various diseases. 3. Genetic modification of iPS cells and iPS cell-derived cell types Many cardiovascular diseases, e.g. of the heart or the respiratory tract, are associated with genetic defects or mutations [...] which patient-specific cells are obtained, reprogrammed into iPS cells , and then genetically corrected . So far, genetic modifications of stem cells have primarily been performed using randomly integrating [...] molecular signalling during respiratory differentiation of human pluripotent stem cells Complex protocols have been developed to differentiate human induced pluripotent stem cells (hiPSC) via endoderm, foregut

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Laboratory areas of the Clinical Department of Haematology

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submission form outside of AMLSG studies Cytogenetic and BCR-ABL analyses are performed at the Institute of Human Genetics . Contact: Phone: +49 511 532 3609 Phone Saturday 8:30-12:30: +49 1761 532 3609 Fax: +49 [...] 6287/4147 Molecular genetic diagnostics Clinical Department Head of department: Prof. Dr. med. Felicitas Thol Head of laboratory: Dr. Inga Sörensen-Zender We offer molecular genetic diagnostics for acute [...] Molecular diagnostics for acute myeloid leukemia: PCR-based detection of chromosomal translocations and genetic aberrations at initial diagnosis on request. Medical laboratory accredited by DAkkS according to

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PNS

Relevance: 68%
 

The latter was originally based on genetic engineering of peripheral glia cells, Schwann cells, but has nowadays evolved to work with Schwann cells derived from human induced pluripotent stem cells (iPSCs) [...] German Armed Forces (2022-2026). We have recently established a protocol for deriving human Schwann cells from human iPSCs and plan to characterize them further with regard to their functional ability in [...] years, studies on peripheral nerve repair and regeneration represent one research focus at our institute. Peripheral nerve lesions result in impairment of quality of life with differing severity for patients

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B Center for Neuromuscular Diseases

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and Institutes of Neuropaediatrics, Cardiology, Pneumology, Immunology, Neuropathology, Neuroradiology and Human Genetics. In addition to clinical assessment, extensive laboratory tests, genetic tests

News

Targeting heart disease

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Vice Director of the MHH Institute for Experimental Haematology . The AAV vectors dock onto the body cell via the vector envelope, the so-called capsid, and transfer their genetic cargo into the cell interior [...] culture with human blood plasma. The two AAV variants also survived this test. They were then loaded with a biomolecule called H19, which has already been successfully tested at the Institute for the treatment [...] "We had several winners in the running and then tested how strongly they were intercepted by the human immune system." Not all gene taxis reach their target Not all vectors that target specific body cells

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