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Subgruppen: Alter, Performance-Status, Geschlecht, Tumorlokalisation (oberer Harntrakt vs. Harnblase), PD-L1-Status, Cisplatinfähigkeit, u.a.) eine deutliche Überlegenheit der neuen Kombination im Vergleich zur [...] Pembrolizumab 200 mg alle 3 Wochen adjuvant oder keine adjuvante Therapie. Die Patienten wurden nach PD-L1-Status, Durchführung einer neoadjuvanten Chemotherapie und dem pathologischen Stadium stratifiziert [...] neoadjuvanten Therapie mit Nivolumab (CheckMate-274) keine statistisch signifikante Abhängigkeit von der PD-L1-Expression nachgewiesen werden konnte. Grad-3+-unerwünschte Ereignisse traten bei 48,4% bzw. 31,8%
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