1186/s13054-021-03584-8. PMID: 33931122 Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA. Autonomous Calcium Signaling in Human [...] print. PMID: 33911000 Etzrodt V, Idowu TO, Schenk H, Seeliger B, Prasse A, Thamm K, Pape T, Müller-Deile J, van Meurs M, Thum T, Garg A, Geffers R, Stahl K, Parikh SM, Haller H, David S. Role of endothelial [...] Bräsen JH, Haller H, Schiffer M. Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model. Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5. PMID: 31776394 Stahl

Research Our group aims at a detailed characterization of the enzyme UDP-glucose pyrophosphorylase (UGP) , a candidate drug target, from pathogenic species and the human host to identify structural and/or [...] human (Homo sapiens). PDB IDs: 4M2A , 8F73 and 4R7P. Images generated with UCSF ChimeraX. Schemes of organisms from Servier Medical Art, provided by Servier, licensed under a Creative Commons Attribution 3 [...] and/or mechanistic differences that would allow the development of specific inhibitors targeting UGP as a novel anti-infective drug target. We have previously studied UGP from the protozoan parasite Leishmania

(Dr. med.) supervisor: PD Dr. Ott, Abt. Gastroenterology a. Hepatology, OE 6810, project: Safety and efficacy of hepatocyte transplantation in a rabbit model of hereditable hypercholesterolemia Final exam [...] Skokowa RUSSIA supervisor: Prof.Dr. R. E. Schmidt, Clinical Immunology, OE 6830, project: C5a anaphylatoxin is a major regulator of FcyRs on alveolar macrophages in immune complex induced lung injury Final

without affecting the recipient's immune system. Our generated HLA-A*02-specific CAR Tregs approach is currently being evaluated in a phase I/II clinical trial. Further Information Publications You can [...] of organs available. Despite the advent of novel immunosuppressants, chronic organ rejection remains a challenge. Maintenance therapy is mandatory after organ transplantations. Immunosuppressive drugs are [...] does not interfere with the immune system and protects the transplanted organs from rejection. It is a promising and affordable way to overcome the problems of immunosuppression, its severe side effects

Iorga B., Fischer M., Geers-Knörr C., Hegermann J., Wrede C., Fiedler J., Kempf H., Franke A., Piep B., Pfanne A., Thum T., Martin U., Brenner B., Zweigerdt R., Kraft T. (2016) “Stiff matrix induces switch [...] (ISSN: 0031-6768), Vol.458(2):337-57 PubMed Iorga B., Blaudeck N., Solzin J., Neulen A., Stehle I., Lopez-Davila A. J., Pfitzer G., Stehle R. (2008) “Lys184 deletion in troponin I impairs relaxation kinetics [...] 77:676-686 PubMed Roels B., Reggiani C., Reboul C., LionneC., Iorga B., Obert P., Tanguy S., Gibault A., Jougla A., Travers F., Millet G., Candau R. (2008) “Paradoxial effects of endurance training and chronic

Stöckel, S.; Neitzke, G.; Frewer, A & Lohff, B.: Geschichte, Theorie und Ethik der Medizin als fester Bestandteil der ärztlichen Ausbildung. Deut. Ärzteblatt 102,6;2005; A330-A334. „...die Grundgedanken des [...] 119 (2018) 96–103 Appendix A doi.org/10.1016/j.yjmcc.2018.04.017 Johann P. Kuhtz-Buschbeck, Angela Drake-Holland, Mark I.M. Noble, Brigitte Lohff, Jochen Schaefer Appendix A: Supplementary data to Rediscovery [...] Klartext, 2009, 119 -135. 2008 Rieder A, Lohff B. [Hrsg.]. Gender Medizin: geschlechtsspezifische Aspekte für die klinische Praxis. 2., überarb. u. erw. Aufl., Wien u.a.: Springer, 2008. XXI, 542 S. Lohff

Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus, López-Dávila A.J., Weber N., Kraft, T., Matinmehr F ., Arias-Hidalgo M., Fernández J [...] 5;97(3):806-24. doi: 10.1016/j.bpj.2009.05.023. Seebohm B, Matinmehr F , Köhler J, Francino A, Navarro-Lopéz F, Perrot A, Ozcelik C, McKenna WJ, Brenner B, Kraft T. [...] Slow-Twitch Fibers, López-Dávila AJ, Chalovich JM, Zittrich S, Piep B, Matinmehr F , Málnási-Csizmadia A, Rauscher AÁ, Kraft T., Brenner B, Stehle R., Front Physiol. 2020 Mar 24;11:144. doi: 10.3389/fphys

induces synaptic plasticity in human cortical neurons. Lenz M, Kruse P, Eichler A, Straehle J, Beck J, Deller T, Vlachos A. (2021) doi: 10.7554/eLife.63026. Technical report: surgical preparation of human [...] VM, Heiland DH, Galanis C, Lenz M, Zhang J, Neidert NN, El Rahal A, Vasilikos I, Kellmeyer P, Scheiwe C, Klingler JH, Fung C, Vlachos A, Beck J, Schnell O. Acta Neurochir (Wien). 2023 Jun;165(6):1461-1471 [...] synaptic transmission and plasticity in the human brain. Within this research focus we implemented a translational and interdisciplinary strategy to assess synaptic transmission and plasticity in the human

e-bikers had a higher risk of a traffic accident (OR=1.63; 95% CI 1.02 to 2.58). Conclusion E-bikes are associated with a lower probability of reaching WHO targets for MVPA due to reduced duration and a reduced [...] Unfallforschung 2022 Exploring European Heavy Goods Vehicle Crashes Using a Three-Level Analysis of Crash Data Schindler R., Jänsch M., Bálint A., Johannsen H. International Journal fo Environmental Research and [...] risk: a prospective observational study Haufe S., Boeck H. T., Häckl S., Boyen J., Kück M., van Rhee C., Graf von der Schulenburg J-M., Zeidler J., Schmidt J., Johannsen H., Holzwart D., Koch A., Tegtbur

Towards a better understanding „Easy German Language as a means to improve German Health Literacy” 14. Januar 2020 Johannes Gutenberg Universität Mainz; Standort Germersheim Gastvortrag im B.A. Sprache [...] tin und -assistentin für Englisch und Französisch (Schwerpunkt Wirtschaft) B.A. Translation an der Universität Leipzig M.A. Medientext und Medienübersetzung an der Universität Hildesheim Wissenschaftliche