Curriculum vitae (CV)

Britta Skawran completed her doctorate in biology at the Institute of Human Genetics at Hannover Medical School (MHH) on the analysis of the TSPY promoter and the role of TSPY in spermatogonial proliferation. This was followed by positions as a research assistant at the Institute of Human Genetics (Prof. Dr. med. Jörg Schmidtke), MHH and at the Institute of Cell and Molecular Pathology (Prof. Dr. med. Brigitte Schlegelberger), MHH.

From 2004 to the end of 2006, Britta Skawran conducted research with Prof. Ludwig Wilkens in the DFG Clinical Research Unit 119. Title: "Global gene and protein expression analyses for the differential diagnosis of morphological subtypes of epithelial liver tumors ".

In 2007, Skawran took over the management of the project in the Clinical Research Unit 119 of the DFG. Title: "Induction of chromosomal instability during the dedifferentiation of hepatocellular carcinomas through alterations in histone modification".

By 2009, Skawran and her team had established the epigenetic focus at the Institute of Cell and Molecular Pathology. Her research focuses on epigenetic modifications in hepatocarcinogenesis and their functional consequences in the context of the alteration of tumor suppressor genes or miRNAs as well as oncogenes or oncomirs.

From 2004 to 2009, Skawran was involved in subproject 3 of the DFG project Compartment - specific gene and protein expression during early phases of bronchiolotis obliterans syndrome after lung transplantation within the KFO123 Lung Transplantation.

Since 2010, Skawran has headed subproject B2, SFB/TRR77 of the DFG Liver Cancer - From Molecular Pathogenesis to Targeted Therapies. Title: "Functional Consequences of Altered microRNA Expression Induced by Histone Deacetylation in Hepatocellular Carcinoma" or "Functional consequences of histone deacetylation-induced alteration of microRNA expression in hepatocellular carcinoma". The project is expected to run until the end of 2013.

Britta Skawran supports the diagnostics of hereditary cancers at the Institute of Cell and Molecular Pathology.

Collaborations:

In her research work, Britta Skawran and her team cooperate with the Ruprecht Karls University, Heidelberg, (UKHD), the German Cancer Research Center Heidelberg (DKFZ), the Institute of Pathology and the Clinical Department of Gastroenterology, Hepatology and Endocrinology, MHH and the Helmholtz Centre for Infection Research, Braunschweig (HZI), "Genome Analytics" platform.

Memberships:

• Society for Human Genetics (GfH)
  

Teaching activities:

• Teaching in the study programmes Biomedicine, Human medicine and Biology