Research

Research ethics and medical ethics methodology working group

 

Research ethics

Ethics^3: Ethics researchers, ethics applications, ethics committees. Problems of and wishes for ethics applications and their review from the perspective of empirical medical and bioethics researchers and members of medical ethics committees in Germany.

Status: Ongoing

Project management:
Dr. phil. Marcel Mertz

Scientific collaboration:
Dr. phil. Ilvie Prince

Student assistant:
Malte Thomalla, B.A.

Funding:
Home remedies

Duration:
May 2024 until probably May 2026

 

EthU: Ethical decision-making in epistemic states of uncertainty in gene therapy and genome editing research projects

Status: Ongoing

Project management:
Dr. phil. Marcel Mertz

Scientific collaboration:
Hélène Nobile, PhD

Funding:
Home remedies

Duration:
March 2022 until probably December 2025

Links to results of the predecessor project (GEENGOV):
Gene and Genome Editing 2022, Science & Engineering Ethics 2022

 

Retreat week "Animal experimentation ethics as an interplay of research ethics, animal ethics and (animal welfare) law. International perspectives on theoretical and cultural differences (TiVE)"

Status: Completed

Project management:
Dr. phil. Marcel Mertz
Dr. PH Hannes Kahrass (former)

Research assistant:
Felicitas Selter, PhD (former)

Student assistant:
Tatiana Hetzel, B.A. (former)

Funding:
Federal Ministry of Education and Research (BMBF)

Duration:
January 2022 to August 2023

Links to results:
Poster (Page 1: Challenges & Solutions), Poster (Page 2: References & Affiliations), Meeting Report (ALTEX), Animals 2025

 

SRR-HCS: Systematic review on ethical reasons for or against conducting human challenge studies

Status: Completed

Project management:
Prof. Dr. Dr. Sabine Salloch
Dr. phil. Marcel Mertz

Scientific collaboration:
Dr. phil. Matthias Katzer

Cooperation partner:
Prof. Dr. Dr. Christoph Schindler (CMO & Head of Center for Clinical Trials, MHH)

Funding:
Home remedies

Duration:
February 2022 to December 2023

Links to results:
Clinical Pharmacology & Therapeutics 2023

 

Alternatives to animal testing: basics, examples and ethical considerations / human-animal relationship from a regulatory and ethical perspective - focus: farm animal husbandry with special consideration of the One Health concept
(projects from "OER for the higher education sector - promoting the creation, Nursing and dissemination of Open Educational Resources at universities in Lower Saxony")

Status: Completed

Project management:
Prof. Dr. Bernhard Hiebl, University of Veterinary Medicine Hannover Foundation (TiHo)
Prof. Dr. Dr. phil. Marcel Mertz

Scientific collaboration (MHH):
Dr. phil. Matthias Katzer
Andrea Nelke, TÄ (former)
Felicitas Selter, PhD (former)
Ines Pietschmann, M.mel (former)

Student collaboration (MHH):
Tatiana Hetzel, B.A. (former)
Ilvie Otto [Prince], B.A. (former)

Funding:
Lower Saxony Ministry of Science and Culture (MWK)

Duration:
December 2020 to October 2023

Links to results:
Materials produced

 

R2N "Replace" and "Reduce" from Lower Saxony - Replacement and supplementation methods for forward-looking biomedical research
Subproject E1: Structure of ethically relevant value judgments in decisions for or against animal testing alternatives

Status: Completed

Project management:
Dr. phil. Marcel Mertz
Dr. PH Hannes Kahrass (former)

Research assistant:
Ines Pietschmann, M.mel (former)

Student assistant:
Ilvie Otto [Prince], B.A. (former)

Funding:
Lower Saxony Ministry of Science and Culture (MWK)

Duration:
October 2018 to December 2022

Links to results:
ALTEX Corners 2019, R2N Poster WinterCamp 2020, Theoretical Medicine and Bioethics 2023, Animals 2024

 

Medical ethical methodology

Ethical attitudes as learning objectives in medical studies

Status: Ongoing

Project management:
Prof. Dr. Dr. Sabine Salloch

Scientific collaboration:
Dr. phil. Matthias Katzer
Dr. phil. Marcel Mertz

Student assistant:
Malte Thomalla

Funding:
German Research Foundation (DFG)

Duration:
July 2024 until probably June 2027

 

Health Technology Assessment (HTA) meta-research: Preparation of a mapping review of "Full-HTA" (with a focus on ethics domains)

Status: Completed

Project management:
Dr. phil. Marcel Mertz

Scientific collaboration:
Dr. PH Hannes Kahrass (former)
Antje Schnarr, M.A. (former)

Cooperation partner:
Prof. Dr. Dr. Clovis Faggion jr. (University Hospital Münster)

Funding:
Home remedies

Duration:
June 2022 to April 2024

Links to results:
International Journal of Technology Assessment in Health Care 2025

 

R2Ethics Methodological quality of (systematic) reviews of normative-ethical and empirical-ethical literature on medical topics. Recording of the state of the art and development of a reporting guideline

Status: Completed

Project management:
Dr. phil. Marcel Mertz

Scientific collaboration:
Dr. PH Hannes Kahrass (former)
Hélène Nobile, PhD
Antje Schnarr, M.A. (former)

PhD students:
Natali Lilie Randjbar Moshtaghin

Student assistant:
Zoë Lüddecke, B.A. (formerly)

Funding:
Home remedies

Duration:
June 2015 to December 2023

Links to results:
BMC Medicine 2016, AEM Annual Meeting 2016, Systematic Reviews 2017, ZEFQ 2017, Equator Network 2018, AEM Annual Meeting 2019, BMC Medical Ethics 2019, Nursing Ethics 2020, Systematic Reviews 2023, Bioethics Open Research 2024

 

Health Technology Assessment (HTA)

T24-03: Sleep quality. Can taking melatonin as a dietary supplement, e.g. in the form of tablets, sprays or soft gums, help to improve sleep?

Status: Ongoing

Project coordination:
Dr. med. Dagmar Lühmann, Institute and Polyclinic for General Medicine, University Medical Center Hamburg-Eppendorf, Hamburg
Dr. phil. Marcel Mertz

Working on social and ethical aspects / Participation WG FE:
Dr. phil. Marcel Mertz
Dr. phil. Ilvie Prince

Funding:
Institute for Quality and Efficiency in Health Care (IQWiG)

Duration:
December 2024 until probably February 2026

Links to results:
Report protocol

 

T24-01: Adhesions in the abdomen: Do non-surgical and non-medicinal procedures help to relieve symptoms?

Status: Ongoing

Project coordination:
Dr. med. Anja Hagen, Institute of Epidemiology, Social Medicine and Public Health Research, Hannover Medical School

Working on social and ethical aspects / participation in WG FE:
Dr. phil. Marcel Mertz
Dr. phil. Ilvie Prince

Funding:
Institute for Quality and Efficiency in Health Care (IQWiG)

Duration:
August 2024 until probably December 2025

Links to results:
Report protocol

 

T23-05: Kinesthetics ("the science of the sensation of movement"): Do care recipients and professional carers benefit from its application?

Status: Completed

Project coordination:
Dr. med. Dagmar Lühmann, Institute and Polyclinic for General Medicine, University Medical Center Hamburg-Eppendorf, Hamburg

Working on social and ethical aspects / participation WG FE:
Dr. phil. Marcel Mertz
Dr. PH Hannes Kahrass (former)

Funding:
Institute for Quality and Efficiency in Health Care (IQWiG)

Duration:
February 2024 to May 2025

Links to results:
Preliminary ThemenCheck report