Curriculum 3rd year

Module title: Pathology

Module code MSE_P_302

Assignment to the study programmes:

Medicine

Lecturer and director:

Prof. Dr. med. Hans H. Kreipe,

Director, Institute of Pathology, MHH

Phone: (532-) 4500, Kreipe.Hans@MH-Hannover.de

Organization:

Dr. med. Matthias Christgen, MD/PhD, Institute of Pathology, MHH

Tel.: (532-) 4488, Christgen.Matthias@MH-Hannover.de

Schedules and appointments: Ms. Kristina Schidlowski

Tel.: (532-) 4454, Schidlowski.Kristina@mh-hannover.de

Academic year / tertial / times:

3rd academic year

Type and scope of courses:

40 hrs. lectures

8 hours of instruction on autopsy cases (dissection room)

40 hours microscopy practical

8 hours seminar

30 hours free microscopy (self-study)

Credit points (ECTS):

Learning objectives:

The teaching of pathology comprises the teaching of the most important characteristics of macroscopically and microscopically detectable pathological changes in cells, tissues and organs together with the underlying pathophysiological principles.

Topics include

- Cell damage and adaptive reactions (e.g. apoptosis, forms of necrosis, hypertrophy, hyperplasia, metaplasia)

- Circulatory disorders (e.g. congestion, edema, thrombosis, embolism, arteriosclerosis, infarction, shock)

- Acute inflammation (e.g. acute exudative forms of inflammation - serous, serous-mucous, fibrinous, purulent, haemorrhagic, necrotizing)

- Chronic inflammation (e.g. chronic granulating inflammation, granulomatous inflammation)

- Pathological immune reactions (e.g. hypersensitivity reactions I - IV according to Coombs and Gell, autoimmune reactions)

- Tumor pathology (e.g. basic terms such as staging, grading, TNM classification, dignity characteristics of benign vs. malignant tumors, examples of mesenchymal/epithelial benign and malignant tumors, hematological neoplasms such as acute and chronic leukemias, mechanisms of invasion and metastasis, immunohistochemical staining to detect e.g. the proliferation index of cells and to detect tissue-specific markers such as prostate-specific antigen).

Approximately 120 specimens are demonstrated as part of the microscopy course and the students microscope them independently and draw the main features.

In the macro course, which is held in seminar form, approx. 100 macroscopic preparations are demonstrated.

All preparations shown in the microscopy and macro course correspond to pathological principles (e.g. granulation tissue as a principle of defect healing or mechanism of organization of e.g. thrombi) or represent a selected entity (e.g. tumors).

In the internship dissection room (PSS) and demonstration dissection room (DSS), students will participate in dissections and be introduced to the macroscopic pathology of the corresponding cases.

Course content:

The lists of topics and specimen lists for lectures and the microscopy course as well as the details of the tertial lessons from A - Z can be found at

https://www.mhh.de/medizinstudium/studienjahre

https://www.mhh.de/medizinstudium/pruefungen

can be viewed.

All teaching and learning materials in ILIAS.

Study achievements:

Compulsory participation in the microscopy course, "internship section hall", "demonstration section hall" and macro course (seminar form).

Examination form:

Structured oral exam (SOE). At two wards (histology, 2 preparations and macroscopy, 3 preparations), knowledge from the lecture, textbooks and pathology course is tested using selected examples from the microscopy course and macro course. At the macro station, the focus is on the material from the DSS, PSS and macro course.

Exam date:

Last week of the module. List of participants and exam day/location can be found at

https://www.mhh.de/medizinstudium/studienjahre

https://www.mhh.de/medizinstudium/pruefungen

Repeat dates:

in the following tertials

Didactic aids:

Provided by the Institute of Pathology for each student:

Script for drawing the histopathological specimens (colored pencils should be brought along!) from the microscopy course and presentation of the most important features of the specimens together with pathophysiological principles.

CD-Rom with the histopathological features of all specimens shown in the microscopy course

List with 75 basic terms and definitions of "General Pathology"

ILIAS: All essential teaching content of the module can be viewed as learning materials.

Learning materials and textbooks:

Mandatory literature:

Contents of the distributed script, contents of the pathology page in ILIAS, CD

Grundmann, "Allgemeine Pathologie und Grundlagen der speziellen Pathologie, 11th edition 2008, Urban & Fischer