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Single center: Hereditary angioedema

 

The Treatment Center for Hereditary Angioedema is part of the Clinical Department of Dermatology, Allergology and Allergy at Hannover Medical School and is listed as an expert center in the current AWMF guideline on hereditary angioedema alongside Berlin, Frankfurt, Mainz, Mörfelden, Munich and Ulm.

Hereditary angioedema (HAE) cannot be cured, but it is very treatable. Early diagnosis and a connection to a specialized department in order to select the optimal individual therapy are important for this rare disease.

 

Competencies of the individual center:


Patient care

Diagnosis and treatment of all angioedema variants, in particular

  • Hereditary angioedema (types I and II) with C1 inhibitor deficiency or dysfunction
  • Factor XII mutation-related (FXII-HAE, formerly known as HAE type III)
  • Plasminogen-HAE (PLG-HAE)
  • Unknown-HAE (HAE with unknown mutation)
  • other bradykinin-mediated angioedema (e.g. triggered by blood pressure medication such as ACE inhibitors)
  • All mast cell/histamine-mediated angioedema (e.g. as part of urticaria/hives)

Studies

In recent years, numerous new treatment options for HAE have been admitted and others are being tested in clinical trials. We will be happy to clarify whether you can currently take part in a study during your visit.

Teaching

HAE and other angioedema variants are taught in undergraduate classes (Dermatology module MSE_P_308, 3rd year of the Human medicine study program and Dermatology and Allergology module, 3rd year of the Dentistry study programme). We also regularly organize training events and patient events on the topic.

Research (current projects)

  • Comparison of different angioedema variants (Clinical Department, therapy, care situation)
  • Identification of biomarkers
  • Research into acute swelling (angioedema) after taking ACE inhibitors and AT receptor blockers (together with the Federal Institute for Drugs, BfArM and the Institute of Human Genetics Bonn)

 

Contact us

 

Further links:

 

Patient organizations:

 

Your contact persons for hereditary angioedema

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Prof. Dr. B. Wedi

Clinical Department of Dermatology and Allergy
Hannover Medical School

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