that major hurdles have been overcome with the help of genetic engineering, including the prevention of the transmission of animal viruses to humans. The most advanced is the xenotransplantation of pig organs [...] succeeded in bringing experts on the burning issues of transplant medicine from the leading research institutions in Europe and the USA to Hannover," said Prof. Dr. Moritz Schmelzle, Director of the Clinical [...] successes have been achieved, for example, with donor lungs whose surface molecules have been genetically modified so that they are not recognized as foreign and rejected by the body. These include non-coding
for clinical application. These technologies were then combined for the generation of murine and human heart muscle tissue from embryonic and induced pluripotent stem cells. For clinical testing of bi [...] iCARE - Induced pluripotent stem cells for clinically applicable heart repair – with six partner institutions, coordinated by Prof. Dr. U. Martin and Prof. Dr. A. Haverich (LEBAO, HTTG , MHH ). The BMBF-funded [...] aims at the generation of a tube-shaped heart tissue, which is based on the contractile function of human pluripotent stem cell-derived cardiomyocytes. The tubular construct represents a single heart chamber
Dr. Dirk Schlüter, Institute for Medical Microbiology and Hospital Epidemiology, MHH Academic Background: Molecular Microbiology, LUH Hannover Nour Elajiry Research Topic: Genetic Mechanisms of Severe [...] infection Supervisor: Prof. Dr. Thomas Pietschmann, Institute for Experimental Virologie, Twincore Academic Background: Biological Sciences, Indian Institute of Science Education and Research Kolkata (IISER [...] RNAs through nanopore sequencing Supervisor: Prof. Dr. Daniel Depledge and Prof. Dr. Lars Dölken, Institute of Virology, MHH Academic Background: Molecular Biotechnology and Bioinformatics, Milano Muhammad
Investigations of human, human pluripotent stem cell-derived cardiomyocytes and animal contractile models in non-pathologic and pathologic conditions Address: Apl. Prof. Dr. Bogdan Iorga Institute for Molecular [...] composition of sarcomeric proteins. Subcellular myofibrils can be obtained from human (e.g., biopsies), human-derived and non-human cardiac and skeletal small muscle samples (e.g., mouse, rat, rabbit, zebrafish [...] and from human stem cells AG Dr. Sarah Konze Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic cardiomyopathy Address Dr. rer. nat. Sarah Konze Institute for Molecular
Hereditary cancers - more common than thought? Dr. med. Bernd Auber, MBA Senior Physician, Institute of Human Genetics, MHH 18.35 - 18.50 | Psycho-oncological services in Lower Saxony and where to find them [...] long-term improvement in patient care from a GP's perspective Kristine Engeleit, Specialist at the Institute for General Medicine, MHH 17.55 - 18.05 hrs | Break 18.05 - 18.20 | Study activities at the CCC
to personal reasons. Jana van Luttikhuizen NETHERLANDS Supervisor: Prof. Dr. Doris Steinemann, Human Genetics, OE 6300, Project: Genomic copy number variations associated with response and resistance to [...] : Prof. Dr. Christine Falk, IFB-Tx, OE 8889, Project: T and NK cell-mediated immune responses of human lung transplant recipients in vivo - impact on the development of transplant arteriosclerosis. Final [...] therapy. Final exam June 2020. Michelangelo Marasco ITALY Supervisor: Prof. Dr. Teresa Carlomagno, Institute for Organic Chemistry / BMWZ, Leibniz Universität Hannover, Project: Structural basis of the activation
& Bucan, V. (2019). Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix [...] antifreeze medium. Freezing and storage take place at the Hannover Unified Biobank (https://www.mhh.de/institute-zentren-forschungseinrichtungen/hannover-unified-biobank-hub). This will provide an alternative [...] donor cells are specifically manipulated. The feasibility of this has already been demonstrated on a genetic basis. The next step is now the transfer to the protein level. This project is funded by the VHV
the SARS-CoV-2 entry in living myocardial slices and human cardiomyocytes Project leader: Prof. Dr. Dr. Thomas Thum Department / Institute: Institute for Molecular and Translational Therapeutic Strategies [...] entry receptor ACE2 in cardiomyocytes Project leader: Prof. Dr. Dr. Thomas Thum Department / Institute: Institute for Molecular and Translational Therapeutic Strategies The coronavirus disease 2019 (COVID-19) [...] the human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) and further validate these findings in living myocardial slices isolated from left ventricular specimens of failing human hearts
Degrees Doctoral Degree Institute of Biomedical Ethics and History of Medicine, Faculty of Medicine, University of Zürich, Switzerland, May 2015 Dissertation Title: “Organ Selling, Human Dignity and its Violation: [...] for the Humanities and Social Sciences). Associate researcher at the Department of Philosophy, University of Calgary, AB, Canada, November 2015 until December 2017. Research assistant in “Human Dignity [...] Caregivers’ Perspective on Biomarkers with Laypersons’ Attitudes towards Genetic Testing of Dementia Prediction”. New Genetics and Society . 39(1): 52-79. doi: 10.1080/14636778.2019.1637719 Alpinar-Sencan
Associate at the Institute of Neuroanatomy and Cell Biology, Hannover Medical School 2000–2002 Ph.D. at the Clinical Department of Neurosurgery, Hannover Medical School, and the Institute of Pharmacology [...] Düsseldorf (Intermediate Examination) Academic Career 2011 – present: Research Group Leader at the Institute of Neuroanatomy and Cell Biology, Hannover Medical School July 2005–October 2005: Visiting Scientist [...] 1, 2363015. *authors contributed equally doi:10.1080/19490976.2024.2363015 Culture Conditions for Human Induced Pluripotent Stem Cell-Derived Schwann Cells: A Two-Center Study. Huang, Z.*, Powell, R*, Kankowski