very happy about Melis Basaran's doctorate! Melis conducted an animal study entitled " Cardiac phenotype and Fgf23/Fgfr4 signaling in animal models with genetic disruption of klotho and phosphate-regulating [...] about Emi Yoshizawa's doctorate! Emi conducted an experimental study entitled " The Hyp mouse as an animal model for X-linked dominant hypophosphatemic rickets: effects of calcitriol on the FGF23-Klotho- [...] dissertation on the topic " Comparison of the calcimimetic R568 and calcitriol in the Hyp mouse, a murine animal model of X-linked hypophosphatemia " and subsequent disputation with magna cum laude. Julia, we wish

Strain archive | Available strains At the Central Animal Laboratory of Hannover Medical School, a wide variety of mouse and rat strains are kept for biomedical research or stored cryopreserved as frozen

events and the promotion of scientific projects and events on animal welfare/animal protection, in particular to prevent cruelty to animals and animal experiments. Board of Trustees Josef Marx Gabriele Marx [...] 200,000 euros Statutory purpose The purpose of the foundation is science and research as well as animal welfare, particularly at Hannover Medical School Form of support The purpose of the foundation is

therapeutic application of human cardiac muscle cells, small animal models are unfortunately unsuitable, since the heart rate in these animals is much higher than in humans, and transplanted human muscle [...] Center. Here you can find further information regarding the importance of animal experiments with monkeys (German only): Animal experiments with monkeys – important questions and answers Aims of the project [...] concepts, a review of the data from in vitro studies in the living organism is inevitable. Only suitable animal models allow such therapeutic applications to be optimized and risks to be minimized before the step

Safety risks and ethics in cell therapies Current State of the Art of iPS based heart repair: Large animal models and clinical translation Current State of the Art of heart support and beyond: Technical devices

prospective recipient’s own endothelial cells. The engineered tissues being produced are tested in large animal models. Vascularized Trachea Replacements At present, there is no suitable material for repairing [...] myocardial patches are being implanted into fibrotic myocardial scar tissue. Both, small and large animal models are used for testing the practicality of this alternative approach.

available at our center (additional techniques can be implemented by mutual agreement): Examples of small animal PET-CT examinations: Serial 3D whole-body examination of glucose metabolism in tumor-bearing mice [...] images. Validation by ex vivo autoradiography / biodistribution measurements . Examples of small animal SPECT-CT examinations: Dopamine receptor SPECT of the basal ganglia (top left), ECG-triggered contrast

nerve fibres is organized and no longer uncontrolled. The same principle applies to RPNIs (see animation below). Here, however, the nerve is only embedded in a small, previously resected piece of muscle [...] the stump. The organized sprouting and increased function can reduce phantom and neuroma pain. Animation RPNI, copyright: stern TV Targeted Sensory Reinnervation (TSR) Sensory feedback on the residual [...] ty. The AMI procedure is usually combined with one of the nerve interventions described above. Animation AMI, copyright: sternTV Osseointegration (OI) An osseointegrated prosthesis is a bone-guided prosthesis

Models of ischemia-/reperfusion induced cholangiopathy in small and large animal models In this project, the workgroup aims to establish and characterize experimental models of ischemia-/reperfusion induced

therapy - Human in vitro models for disease modeling and drug screening - Improving translational animal models and testing new therapeutics Main tasks Work Package 8 - Establish MI model, immunosuppression