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Further training / events

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Henriettenstift Hannover Prof. Dr. med. Christian Hartmann, Institute of Pathology/Neuropathology, MHH Prof. Dr. med. Friedrich Feuerhake, Institute of Pathology/Neuropathology, MHH Please click here Between [...] 2026 17:15-19:00 Speaker: Prof. Dr. Dr. Arno Villringer, Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig Please click here Interdisciplinary Research in Neurological [...] Wednesday, January 21, 2026 17:15-19:00 Speaker: Dr. Melanie Boltzmann, Institute for Neurorehabilitative Research (InFo), Associated Institute of the Hannover Medical School BDH Clinical Department Hessisch Oldendorf

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Research

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cardiac support system. With the help of induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells, heart muscle cells can be produced. These should form the basic building [...] organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis (from left) How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers [...] with more than six million euros, of which the Medical School Hannover (MHH) is the coordinating institution. This highly interdisciplinary network of academic and industrial scientists is composed of stem

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The ZSE at a glance

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Structure of the ZSE The Centre for Rare Diseases (ZSE) was founded in 2011 as part of the Institute of Human Genetics at Hannover Medical School and has been an independent department since 2018. There are [...] Centre for Rare Diseases The Centre for Rare Diseases (ZSE) is an independent interdisciplinary institution of Hannover Medical School (MHH). The task of the ZSE is to improve medical care for people with [...] cooperates with other university Centres for Rare Diseases, hospitals and other medical facilities or Institutions beyond the boundaries of the MHH and is networked throughout Germany. In addition, the ZSE of

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Hannover Transplant Summit 2024

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that major hurdles have been overcome with the help of genetic engineering, including the prevention of the transmission of animal viruses to humans. The most advanced is the xenotransplantation of pig organs [...] succeeded in bringing experts on the burning issues of transplant medicine from the leading research institutions in Europe and the USA to Hannover," said Prof. Dr. Moritz Schmelzle, Director of the Clinical [...] successes have been achieved, for example, with donor lungs whose surface molecules have been genetically modified so that they are not recognized as foreign and rejected by the body. These include non-coding

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RG Gruh

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for clinical application. These technologies were then combined for the generation of murine and human heart muscle tissue from embryonic and induced pluripotent stem cells. For clinical testing of bi [...] iCARE - Induced pluripotent stem cells for clinically applicable heart repair – with six partner institutions, coordinated by Prof. Dr. U. Martin and Prof. Dr. A. Haverich (LEBAO, HTTG , MHH ). The BMBF-funded [...] aims at the generation of a tube-shaped heart tissue, which is based on the contractile function of human pluripotent stem cell-derived cardiomyocytes. The tubular construct represents a single heart chamber

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Students 2025

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Dr. Dirk Schlüter, Institute for Medical Microbiology and Hospital Epidemiology, MHH Academic Background: Molecular Microbiology, LUH Hannover Nour Elajiry Research Topic: Genetic Mechanisms of Severe [...] infection Supervisor: Prof. Dr. Thomas Pietschmann, Institute for Experimental Virologie, Twincore Academic Background: Biological Sciences, Indian Institute of Science Education and Research Kolkata (IISER [...] RNAs through nanopore sequencing Supervisor: Prof. Dr. Daniel Depledge and Prof. Dr. Lars Dölken, Institute of Virology, MHH Academic Background: Molecular Biotechnology and Bioinformatics, Milano Muhammad

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Lysosomal storage diseases with kidney involvement (Fabry disease, cystinosis)

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in an interdisciplinary team from various specialties (neurology, cardiology, ophthalmology, human genetics, etc.) Clinical studies in the field of Fabry disease (including new treatment options) Research [...] Center MHH. The Center also carries out the necessary examinations to clarify the presence of this genetic hereditary disease in cooperation with other disciplines. Furthermore, patients are evaluated with [...] course of treatment. Diseases Fabry disease Cystinosis Competencies of the center Enzymatic and genetic diagnostics to clarify Fabry disease Patient care with regard to the coordination and performance

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ZSE - Basic centers

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Example of Li-Fraumeni syndrome LFS is a genetic disease that is associated with a significantly increased risk of various types of cancer. The underlying genetic defect can lead to the multiple occurrence [...] Neuropathology Drug therapy Pharmacology Clinical pharmacology Psychopharmacology Basic sciences Human genetics Central Laboratory Biochemistry Glycoanalytics Biometry Neuroanatomy Psyche Psychiatry Psychosomatics

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Disease modeling

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in a dish Disease modeling using human induced pluripotent stem cells (hiPSCs) is a powerful and evolving approach in biomedical research. Patient- or donor-derived human iPSCs are differentiated into relevant [...] possibility to create tailored genetic models allows investigation of disease pathways with unparalleled accuracy. These diseases models are instrumental in understanding genetic disorders and developing targeted [...] modeling platforms are available in 2D monolayer or co-culture systems as well as 3D multicellular human cardiac organoids. Living heart slices We employ a combination of advanced physiological techniques

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working groups

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Investigations of human, human pluripotent stem cell-derived cardiomyocytes and animal contractile models in non-pathologic and pathologic conditions Address: Apl. Prof. Dr. Bogdan Iorga Institute for Molecular [...] composition of sarcomeric proteins. Subcellular myofibrils can be obtained from human (e.g., biopsies), human-derived and non-human cardiac and skeletal small muscle samples (e.g., mouse, rat, rabbit, zebrafish [...] and from human stem cells AG Dr. Sarah Konze Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic cardiomyopathy Address Dr. rer. nat. Sarah Konze Institute for Molecular

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