Neuropsychiatric diseases As an animal model for neuropsychiatric diseases we use, among other things, prepulse inhibition (PPI) of the acoustically induced startle response. This is a measure of an automatic [...] which is reduced in some neuropsychiatric disorders, such as schizophrenia and Tourette's syndrome. Animal experimentally induced PPI deficits are therefore considered valid models to study these disorders

published study demonstrated the correction of the rare metabolic disease tyrosinemia in experimental animals by injecting adeno-associated viruses (AAV) as a vehicle for CRISPR-Cas9. Various variants of the [...] development. They investigate novel therapeutic concepts in different in vitro , organoids, and small animal model systems to identify effective therapeutic targets for this largely intractable cancer. Research

ce in-situ hybridization (FISH) in the diagnosis of hematological diseases Animal experimental methods (introduction) Animal experimental methods (specific courses) 2.2 Special Seminars: Molecular biological [...] as ‘Presentation techniques', ‘Scientific writing', ‘Research ethics', ‘Gene technology safety', ‘Animal experiments' as well as career perspectives. Excursions to industry also take place regularly. See [...] institutes to provide up-to-date technologies and support (e. g. gene expression profiling, experimental animal work, confocal microscopy for in vivo imaging, and proteomics). A huge library with relevant textbooks

significance and better establishment of organotypic in vitro systems, which are alternatives to animal testing based on the 3R principle (Replace, Reduce, Refine), in inhalation toxicology. Before moving

Hannover, the Fraunhofer Institute for Toxicology and Experimental Medicine, the Institute of Farm Animal Genetics of the Friedrich-Loeffler-Institute (FLI) Mariensee, the Helmholtz Centre for Infection

proteases on the radiation effect in tumor therapy" 1986 Veit Bendel (Dr. med.) Topic: "Experimental animal studies on the effect of total lymphatic irradiation on the tolerance of skin grafts" 1979 Fridtjof

kids Small games 1 Little games 2 Playing with the towel Playing with the ball A day in the snow The animal world The little star A trip to the beach A dream of a fairytale forest The fire department Taffi

organisms with a fully known microbial status including germ-free animals, which are devoid of all living microorganisms, and animals colonized with specific microbial species. The insights gained from [...] Multiple diseases have been associated with shifts in microbial composition and function. Gnotobiotic animals are valuable experimental model to investigate the function and the role of the intestinal microbiota [...] ranges of diseases and health conditions. To ensure their strict microbiological status, gnotobiotic animals are housed in specialized equipment such as isolators. The Gnotobiotic unit is a state-of-the-art

meeting patients expectations. In many years of research in peripheral nerve regeneration, using animal models and in vitro systems, we contributed to the clinical approval of chitosan-based nerve guides [...] system. In this project we collaborate with the Gnotobiotic Group at the MHH-Institute for Laboratory Animal Science (Dr. Marijana Basic, Dr. Silvia Bolsega) and colleagues from Italy (Prof. Giulia Ronchi,

disorders Development of psychiatric treatment regimen for patients with ethyltoxic liver cirrhosis Animal models for alcohol disorders Post mortem studies investigating the tissue-dependent regulation of [...] followed by its derivative's consecutive expression, the alpha-melanocyte-stimulating hormone in an animal model for alcohol addiction. 2016-2017: IFB-TX (integrated science and treatment center transplantation)