for other neurodegenerative diseases, the biochemist suspects. Next, the research team would like to test the results in the animal model and use the MS expertise available in Lower Saxony for this. "For
nutrient solution, these heart muscle slices live and continue to beat for many days to weeks. "We first test the mode of action of our circRNA candidates in the living heart slices," says the scientist. In a
Gastroenterology, Hepatology, Infectiology and Endocrinology. The PIECES project offers the opportunity to test the wide range of preventive measures, whose effectiveness has already been proven in controlled
to the target cell in the lungs that is affected by the virus. The efficacy of the drug is being tested on human lung tissue sections as well as in 3-D cell cultures from human lung epithelium. "If all
we collected cough swabs from healthy children aged three weeks to six years for the first time, tested them for the microorganisms present and compared them with those from cystic fibrosis sufferers of
tubes, which is why PCD is often associated with an unfulfilled desire to have children. A genetic test provides the final certainty for an exact diagnosis. "At the MHH, we can carry out an examination
available to all patients as an established method in the future, a multicenter clinical trial is to test the new therapeutic approach under standard conditions. The German Federal Ministry of Education and
by the Paul Ehrlich Institute," says Dr. Lubomir Arseniev, head of the CTC. Only after clinical testing does the new preparation then have a chance of being approved on the market. kp More information
the anti-tumor response. If the therapeutic approaches work in the mouse model, they could then be tested in a human clinical trial. "This is an ambitious four-year program," Dr. Heinrich admits. "However
cell culture were completely spared. Two further HLA receptors are currently being constructed and tested. "There are several genes in the HLA system, which also exist in many variants," says the young