Our group investigates the role of CD8 T cells in acute and chronic infection models as well as in animal models of gastrointestinal tumors. A particular research focus of our group is hepatocellular carcinoma [...] pathogen-specific T cells. The focus of our oncological investigations is the establishment of practical animal models for hepatocellular carcinoma and other gastrointestinal tumors (e.g. pancreas) and the development
consider your request. You will hear from us as soon as possible. Kind regards, the team of the Central Animal Laboratory
s are required. These methods should allow for the tracking of the cells in not only preclinical animal models but later also in patients. In the present study, the research team led by Professor Dr. Ulrich [...] this might allow for the monitoring of survival and distribution of transplanted stem cells in both animal model and patients. In fact, using modern clinical imaging methods, these modified iPS cells could
new recombinant coagulation factor concentrates, which are produced completely free of human and animal proteins. In addition, projects on patient-reported outcomes (PROs) and quality of life are being [...] analysis), signal transduction, translational epigenetics, immunophenotyping and functional analysis in animal models). - The research group 5659 "TARGET-MPN" (spokesperson: Prof. Dr. F. Heidel) and the Emmy
very happy about Melis Basaran's doctorate! Melis conducted an animal study entitled " Cardiac phenotype and Fgf23/Fgfr4 signaling in animal models with genetic disruption of klotho and phosphate-regulating [...] about Emi Yoshizawa's doctorate! Emi conducted an experimental study entitled " The Hyp mouse as an animal model for X-linked dominant hypophosphatemic rickets: effects of calcitriol on the FGF23-Klotho- [...] dissertation on the topic " Comparison of the calcimimetic R568 and calcitriol in the Hyp mouse, a murine animal model of X-linked hypophosphatemia " and subsequent disputation with magna cum laude. Julia, we wish
Strain archive | Available strains At the Central Animal Laboratory of Hannover Medical School, a wide variety of mouse and rat strains are kept for biomedical research or stored cryopreserved as frozen
events and the promotion of scientific projects and events on animal welfare/animal protection, in particular to prevent cruelty to animals and animal experiments. Board of Trustees Josef Marx Gabriele Marx [...] 200,000 euros Statutory purpose The purpose of the foundation is science and research as well as animal welfare, particularly at Hannover Medical School Form of support The purpose of the foundation is
therapeutic application of human cardiac muscle cells, small animal models are unfortunately unsuitable, since the heart rate in these animals is much higher than in humans, and transplanted human muscle [...] Center. Here you can find further information regarding the importance of animal experiments with monkeys (German only): Animal experiments with monkeys – important questions and answers Aims of the project [...] concepts, a review of the data from in vitro studies in the living organism is inevitable. Only suitable animal models allow such therapeutic applications to be optimized and risks to be minimized before the step
Safety risks and ethics in cell therapies Current State of the Art of iPS based heart repair: Large animal models and clinical translation Current State of the Art of heart support and beyond: Technical devices
prospective recipient’s own endothelial cells. The engineered tissues being produced are tested in large animal models. Vascularized Trachea Replacements At present, there is no suitable material for repairing [...] myocardial patches are being implanted into fibrotic myocardial scar tissue. Both, small and large animal models are used for testing the practicality of this alternative approach.