effective and fast. To ensure this at all times, the organ donor's blood and tissue are extensively tested before the organs are allocated and transplanted - around the clock. With their 24-hour diagnostic [...] diagnostic Institutes. The immunological profile of the donor is created in his Institute. Compatibility tests are also carried out between donor and recipient. The Institutes of Pathology, Clinical Chemistry
Developing replacement and supplementary methods for animal experiments and thus avoiding animal testing is the goal of the "Micro-Replace Systems" research network led by Professor Dr. André Bleich, Director [...] experiments. Stem cells grow into mini organs The network is primarily concerned with reducing animal testing in basic research. "It is precisely there that the number of animal experiments has been constant [...] information on how research is currently working to reduce, improve or completely replace animal testing, visit https://www.3r-forschung.de/ .
of Heidelberg, significantly reduced the hepatitis D viral load in the blood serum and liver of the test subjects. Treatment with the novel entry inhibitor is therefore a promising strategy for patients [...] successfully treating hepatitis D has come much closer. The antiviral activity of Bulevirtide was tested in a multicenter phase II study in a total of 120 HBV/HDV-positive patients, 59 of whom had already [...] over 24 weeks significantly reduced the concentration of HDV RNA in the blood serum and liver of the test subjects and was well tolerated by the study participants. Although the concentration of hepatitis
basic immunization, you can expect to be protected for at least 25 years. Titer determination Titer tests for hepatitis A are only useful in the run-up to a possible vaccination in order to rule out a previous [...] to the vaccination schedule: 0-1-6 months. Titer determination Before basic immunization: A blood test before the first vaccination will determine whether you have already had a hepatitis B infection. [...] immunization can be started. After basic immunization: 4-6 weeks after the third vaccination, a blood test will check whether you have developed a sufficient antibody titer (anti-HBs). If the titre is < 100
cardiac tissue (BCTs) with neonatal rat cardiomyocytes. Together with Leibniz University Hannover, we tested matrices for tissue engineering, including methacrylated alginate and hyaluronic acid blends and [...] murine and human heart muscle tissue from embryonic and induced pluripotent stem cells. For clinical testing of bioartificial cardiac tissue, we currently aim at standardizing procedures and establishing validation [...] had been available previously, we developed a multimodal bioreactor for cultivation and functional testing of miniaturized bioartificial cardiac tissue. These small-scale tissues are especially suitable for
Institute of Human Genetics at the MHH, genetic testing is carried out on our patients. Whole-genome sequencing (WGS) is used as the procedure. Genetic testing is carried out with the aim of individualizing
run until July 15, 2025 (receipt of the application at the MHH). The information day (with knowledge test) provided for in the procedure is scheduled for the end of July 2025. The admission procedure takes [...] the admission procedures for the summer and winter semesters, an information day and the knowledge test provided for in the admission regulations take place at the MHH at the end of January and end of July
virus needs for its reproduction," says Professor Schambach. Efficacy of RNAi candidates successfully tested in lung tissue The RNAi technology uses molecular methods to attack the Achilles' heel of the viruses [...] cted development pipeline, this process could be shortened to a few weeks. "We have successfully tested the efficacy of our RNAi candidates on human lung tissue sections as well as in 3D cell cultures [...] for other virus types In the next step, the efficiency and safety of the RNAi candidates will be tested in animal models. In addition, the RNA therapeutic agent is not to be administered with a syringe
511 532 5062 E-mail AORTIC CLAMP REPLACEMENT IN YOUNG PATIENTS New treatment option successfully tested in Europe-wide study Young patients in particular face a dilemma when choosing an aortic valve r [...] decellularized homografts, have been developed at Hannover Medical School and have now been successfully tested in a Europe-wide study funded by the European Commission¹. Cell-free heart valves represent an excellent [...] Surgery (HTTG) under the direction of Prof. Dr. Axel Haverich has been dedicated to the clinical testing of new therapeutic strategies for the aortic valve and the aortic arch for many years. For example