T Sparwasser, M Lochner. 2019. Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile . Eur J immunol. 49(5):747-757. Friedrich, [...] T Sparwasser, M Lochner. 2017. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium . PloS Pathog. 13(5):e1006357. Yang, BH [...] Ponimaskin, WR Abraham, R Muller, M Lochner*, T Sparwasser*. 2014. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. Nat Med 20(11):1327-1333. (*contributed equally)
contamination with pathogens or undesirable effects, ATMPs must be manufactured under strictly controlled conditions in accordance with the high quality specifications of good manufacturing procedure (GMP) [...] Cellular Therapy Centre (CTC) department. But the institute offers more than manufacturing and quality control. One floor below, the ATMP-GMPDU development department provides MHH research groups with its expertise
The ablation itself is robotic and takes only three to six minutes. The urologist controls the process and can control the intensity or interrupt the procedure at any time. After the operation, the patient
an intermediate-complexity system, LMS provide a unique opportunity to study cardiac tissue in a controlled yet physiologically relevant environment. This platform allows for precise modulation of myocardial [...] infarction, and pathological remodeling in heart failure. By replicating disease conditions in a controlled environment, we aim to identify and validate effective compounds that can improve cardiac function
harmful tobacco products. This debate provides a platform for young people, policy makers and tobacco control advocates worldwide to discuss the issue and urge governments to take action to protect young people [...] smoking, you are not only doing your own health a favor, but also protecting the health of others. Control over your own life After quitting smoking, the ex-smoker is no longer a permanent victim of his
Soetje B, Haffner D. Orphanet J Rare Dis. 2022; 17:122. here Fibrocystin is essential to cellular control of adhesion and epithelial morphogenesis. Ziegler WH, Soetje B, Marten LP, Wiese J, Burute M, Haffner [...] Cell . 2018; 29: 2317-2325. here E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Rübsam M, Mertz AF, Kubo A, Marg S
infection control and pandemic surveillance. Optimization of functions, deployment and usability together with a roll-out throughout the network will be fostered to facilitate COVID-19 infection control in the [...] rogramm PREPARED (WP 10) / HygSupport - Human resources management for infection prevention and control teams Project leader: Prof. Dr. Thomas von Lengerke Department / Institute: Department of Medical [...] which measures may promote infection preventive leadership by hospital epidemiologists, infection control nurses, and possibly specialized engineers. Firstly, a scoping review was conducted ( DOI: 10.1016/j
many areas of diagnostics, including after kidney transplantation, and helps us to determine and control our clinical approach in many areas. We are therefore all the more pleased to be able to hold another
the transplant. Such personalized immunosuppression is certainly not possible via trough level control. The Torque Teno virus or the Torque Teno viral load has emerged as an interesting new biomarker
cancer risk factors that can be influenced . Tobacco consumption is considered the most important controllable risk factor. In addition, diet, exercise and body weight have a particularly high potential for