2024 Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo Abbas N, Haas JA, Xiao K, Fuchs M, Just A, Pich A, Perbellini F, Werlein C , Ius F, Ruhparwar A, Fiedler J, Weber N [...] Hartinger S, Haferlach T, Kreipe HH , Hammersen J, Hamadanchi A, Otto S, Schulze PC, Bürckenmeyer F, Teichgräber U, Hochhaus A, Witte OW, Günther A, Schrenk KG. Ann Hematol. 2024 Jan;103(1):363-365. doi: 10 [...] e Cholestasis Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek

human (Homo sapiens). PDB IDs: 4M2A , 8F73 and 4R7P. Images generated with UCSF ChimeraX. Schemes of organisms from Servier Medical Art, provided by Servier, licensed under a Creative Commons Attribution 3 [...] Research Our group aims at a detailed characterization of the enzyme UDP-glucose pyrophosphorylase (UGP) , a candidate drug target, from pathogenic species and the human host to identify structural and/or [...] and/or mechanistic differences that would allow the development of specific inhibitors targeting UGP as a novel anti-infective drug target. We have previously studied UGP from the protozoan parasite Leishmania

RNAs as a revolutionary pharmacological tool to combat cardiovascular diseases. Contact: XXXX Key references: Abbas N, Haas JA, Xiao K, Fuchs M, Just A, Pich A, Perbellini F, Werlein C, Ius F, Ruhparwar [...] Costa A, Cushman S, Neufeldt D, Rode L, Schmidt A, Juchem M, Leonardy J, Büchler G, Blume J, Gern OL, Kalinke U, Wen Tan WL, Foo R, Vink A, van Laake LW, van der Meer P, Bär C, Thum T. (2022) A circular [...] Heart Failure & Remodeling Heart failure is a complex clinical syndrome with a multifaceted pathophysiology. It is a severe condition resulting from ventricular dysfunction, and its prevalence is increasing

Dannecker C, Dietl A, Sevnina A, Mergel F, Lotz L, Hack CC, Ehret A, Gantert D, Martignoni F, Cieslik JP, Menke J, Ortmann O, Stromberger C, Oechsle K, Hornemann B, Mumm F, Grimm C, Sturdza A, Wight E, Loessl [...] Jarkovsky J, Persson J, Raspagliesi F, Novak Z, Jaeger A, Capilna ME, Weinberger V, Klat J, Schmidt RL, Lopez A, Scibilia G, Pareja R, Kucukmetin A, Kreitner L, El-Balat A, Pereira GJR, Laufhütte S, Isla-Ortiz [...] Bousset K, Hülse F, Mao Q, Wang Y, Jentschke M, Böhmer G, Strauß HG, Hirchenhain C, Schmidmayr M, Müller F, Runnebaum I, Hein A, Stübs F, Koch M, Ruebner M, Beckmann MW, Fasching PA, Luyten A, Dürst M, Hillemanns

Moran-Losada P, Wiehlmann L, Koch A, Chopra H, Pabst O, Hoffmann A, Klopfleisch R (2013) THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) [...] Oncogene. 35(29):3872-9 Koch A, Saran S, Tran DD, Klebba-Färber S, Thiesler H, Sewald K, Schindler S, Braun A, Klopfleisch R, Tamura T. (2014) Murine precision-cut liver slices (PCLS): a new tool for studying [...] J. Biol. Chem. 276 (5), 3017-23 Koch A, Mancini A, Stefan M, Niedenthal R, Niemann H and Tamura T (2000) Direct Interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase c-Abl

Knipel V, Windisch W, Mahadeva R, Bals R, Koczulla R, Barrecheguren M, Miravitlles M, Janciauskiene S, Stickel F, Lammert F, Liberal R, Genesca J, Griffiths WJ, Trauner M, Krag A, Trautwein C, Strnad P; European [...] monocytic interleukin-1β? A preliminary study. Agné A, Richter K, Tumpara S, Sauer AL, Beckert F, Wrenger S, Zakrzewicz A, Hecker A, Markmann M, Koch C, Zajonz T, Sander M, Böning A, Padberg W, Janciauskiene [...] Teufel A, Feldman A, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Ridinger M, Wodarz N, Soyka M, Rietschel M, Kiefer F, Weber T, Marhenke S, Vogel A, Hinrichsen H, Canbay A, Schlattjan

Nolte E, Balicer R (eds.) (2021). Handbook Integrated Care Second Edition. Springer Nature Switzerland AG 2021 Amelung VE , Eble S, Sjuts R, Ballast T, Hildebrandt H, Knieps F, Lägel R, Ex P (eds.) (2020) [...] V, Suter E, Goodwin N, Balicer R, Beese A-S (eds). Handbook of Integrated Care Third Edition. Springer Nature Schwartz FW, Walter U, Siegrist J, Kolip P, Leidl R, Busse R, Amelung V , Dierks M-L (eds.) [...] Balicer R, Nolte E, Suter E [eds]. Handbook Integrated Care. Springer International Publishing 2017 Amelung VE , Eble S, Hildebrandt H, Lägel R, Knieps F, Ozegowski S, Schlenker RU, Sjuts R [Eds]: Patient

0354-7 Tetzlaff F, Bremer K, Brender R & Groeger-Roth F (2024). The green list guide: Digital offers newly bundled. Forum Crime Prevention, 2/2024, 18-20 Brender R, Gorenoi V, Hagen A (2021). Identification [...] Brender R, Tetzlaff F, Walter U & Groeger-Roth F (2024). Finding suitable prevention measures - The Green List guide supports with new search functions. Forum Crime Prevention, 3/2024, 3-5 Brender R , Bremer [...] Kula A, Brender R , Bernartz KM, Walter U (2024). Waist circumference as a parameter in school-based interventions to prevent overweight and obesity - a systematic review and meta-analysis. BMC Public

g M, Mrugalla A, Helms F, Sedding D, Haverich A, Wilhelmi M, Böer U. Tissue Eng Part A. 2019 Jul;25(13-14):936-948. doi: 10.1089/ten.TEA.2018.0172. Epub 2019 Jun 14. PMID: 30648499 3. A 3-Layered Bioartificial [...] Lau S, Eicke D, Carvalho Oliveira M, Wiegmann B, Schrimpf C, Haverich A, Blasczyk R, Wilhelmi M, Figueiredo C, Böer U. Tissue Eng Part A. 2018 Mar;24(5-6):432-447. doi: 10.1089/ten.TEA.2016.0541. Epub 2017 [...] vascular prostheses, a promising replacement for arteries or veins. Such artificially produced vessels, especially if they are based on the body's own starting products such as fibrin, have a low risk of thrombosis

G, Beschorner R, Coras R, Keyvani K, Kohlhof P, Diomedi-Camassei F, Herold-Mende C, Giangaspero F, Rushing E, Giannini C, Korshunov A, Jones DTW, von Deimling A: FGFR1:TACC1 fusion is a frequent event [...] Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM [...] Carotid Arteries in a Rat Subcutaneous Implantation Model and in a Human In Vitro Model. Tissue Eng Part A. 2018; 24(3-4): 310-321 Kar S, Bali KK, Baisantry A, Geffers R, Hartmann C , Samii A, Bertalanffy H: