(cardiomyocytes); pink: CD31 (endothelial cells); blue: DAPI. Scale bar: 200 µm. (B) Schematic of an HFO compared to the early embryonic heart/ foregut region. Adapted from Drakhlis et al., Nature Biotechnology [...] Coffee M, Franke A, Schwanke K, Leffler A, Luanpitpong S, Issaragrisil S, Fischer M, Zweigerdt R. Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation

the genome and correction of genetic defects with the help of the cell's own repair mechanisms. Compared to conventional gene targeting and the use of integrating vectors, the ZFN, TALEN or CRISPR/Cas9-based [...] cell types produced from iPS cells, which are a "juvenile" cell source, unexpectedly only have a comparatively low proliferative potential. We are currently investigating the phenomenon of early senescence

a small proportion is converted into milk, eggs or meat, which leads to higher land requirements compared to direct use for plant-based foods. In addition, the land required for fodder cultivation leads [...] e contribution to reducing food waste. In 2023 alone, we were already able to save 16% of waste compared to the previous year. The overproduction of patient food is increasingly being reduced through

Alpinar-Sencan, Z. , Lohmeyer, L., Schicktanz, S. (2020). “Planning Later Life with Dementia: Comparing Family Caregivers’ Perspective on Biomarkers with Laypersons’ Attitudes towards Genetic Testing [...] nberg) 2021. Hearing Diverse Perspectives to Improve Future Practices in Dementia Medicine: A Comparative Analysis of Attitudes towards Early Diagnosis and Prediction of Dementia Across Stakeholder Groups

Epping J*, Safieddine B*, Geyer S, Tetzlaff J (2021). Are prevalences in survey and routine data comparable? Prevalence of myocardial infarction in health insurance data from the AOK Lower Saxony and in [...] (2021). Completely different or quite similar? The sociodemographic structure of the AOK Lower Saxony compared to the general and working population in Lower Saxony and Germany. Health Care; 83, 2nd Suppl, S77-86 [...] after treatment for primary breast cancer over a six-year period: Results from a prospective study comparing patients with the general population. Supportive Care in Cancer, 21 (7): 1901-1909. dx.doi.org/10

study has shown that, compared to work setting, the general self-efficacy of German midwives, years providing intrapartum care and sources of knowledge about normal birth had comparatively little impact on [...] order to record basic structural parameters of the degree programs and to serve as a basis for comparative and cross-locational analyses as well as for quality development. The project is being carried [...] and whole communities. To inform a lasting and meaningful progress, it is essential to collect and compare data about service design, health indicators and outcomes on a local, regional and international

approach is being tested in a randomized controlled trial (RCT): 125 treated test subjects are being compared with 125 patients receiving conventional psychotherapy. The study is being comprehensively scie [...] data. The predictive accuracy for the risk of developing a selected cancer will be explored and compared with a statistical algorithm developed in parallel. In addition, the ethical implications of using [...] use the "AOK-Junior" program to identify illnesses in children and adolescents at an earlier stage compared to standard care and guide them towards appropriate measures. In addition, the satisfaction of the

approaches for viral lung infections. The aim of this study is to verify the impact of inhalation comparing to conventional application procedures for respiratory viral diseases, especially as a post-exposure

successful treatment procedure. Longer life expectancy and higher quality of life are advantages compared to dialysis. However, the long-term results of transplantation are not satisfactory. In the first

g patterns and their environmental determinants in the spinal cord injury (SCI) population: A comparative analysis across eleven European countries implementing the International Spinal Cord Injury Community